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Modified and stabilized GDF propeptides and uses thereof

  • US 8,222,384 B2
  • Filed: 05/04/2009
  • Issued: 07/17/2012
  • Est. Priority Date: 02/08/2001
  • Status: Expired due to Fees
First Claim
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1. An isolated nucleic acid molecule encoding a GDF-8 propeptide comprising a nucleic acid sequence that encodes a GDF-8 propeptide that is at least 95% identical to SEQ ID NO:

  • 5 and that is modified at the aspartate residue corresponding to aspartate 76 of SEQ ID NO;

    5.

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