Reconstitution assembly, locking device and method for a diluent container

• US 8,226,627 B2
• Filed: 08/12/2008
• Issued: 07/24/2012
• Est. Priority Date: 09/15/1998
• Status: Expired due to Term

• Current Assignee: Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Fowles, Thomas A., Weinburg, Robert J.
• Primary Examiner(s): Zalukaeva, Tatyana
• Assistant Examiner(s): Chapman, Ginger T
• Application Number:
  US12/189,966
• Publication Number:
  US 20080300570A1
• Time in Patent Office: 1,442 Days
• Field of Search: 604/410, 604/111, 604/411, 604/520, 604 89- 91, 604/110
• US Class Current: 604/410
• CPC Class Codes: A61J 1/10 Bag-type containers
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61J 1/1475 Inlet or outlet ports
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2013 having two piercing ends
• CPC Class Codes: A61J 1/2051 having tap means, e.g. tap means activated by sliding
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents

Abstract

A reconstitution assembly includes: a flexible bag containing a diluent; a drug vial containing a drug; a reconstitution device further comprising: a first sleeve connected to the first container; a second sleeve connected to the second container, the second sleeve being associated with the first sleeve and movable axially with respect thereto from an inactivated position to an activated position; a piercing member positioned in the sleeves, the piercing member providing a fluid pathway between the bag and vial when the sleeves are in the activated position.

Claims

1. A reconstitution assembly comprising:

a flexible bag containing a diluent;

a drug vial containing a drug; and

a reconstitution device comprising;

a first sleeve having a port connector assembly including an attaching member and a membrane tube, wherein the attaching member is configured to receive the membrane tube, the membrane tube configured to be connected to the flexible bag;

a second sleeve connected to the drug vial, the second sleeve being associated with the first sleeve and movable axially with respect thereto from an inactivated position to an activated position;

a piercing member positioned in the sleeves, the piercing member providing a fluid pathway between the bag and vial when the sleeves are in the activated position.

2. The assembly of claim 1 further comprising a device configured to prevent premature activation of the device.

3. The assembly of claim 1 wherein the first sleeve is connected to the flexible bag in a low energy e-beam field.

4. The assembly of claim 1 wherein the second sleeve is connected to the drug vial in a low energy e-beam field.

5. The assembly of claim 1 further comprising a device configured to hermetically seal the piercing member.

6. A reconstitution assembly comprising:

a flexible bag containing a diluent;

a drug vial containing a drug; and

a reconstitution device comprising;

a first sleeve connected to the flexible bag;

a second sleeve connected to the drug vial, the second sleeve being associated with the first sleeve and movable axially with respect thereto from an inactivated position to an activated position;

a piercing member positioned in the sleeves, the piercing member providing a fluid pathway between the bag and vial when the sleeves are in the activated position; and

a removable apparatus configured to prevent premature activation of the reconstitution device.