Ultrasonic catheter power control
First Claim
1. A method of treating an occlusion at a treatment site within a patient'"'"'s vasculature comprising:
- providing an ultrasonic catheter having a distal region, a proximal region opposite the distal region, a fluid delivery lumen having at least one opening in the distal region, and an ultrasound radiating member positioned within the distal region;
positioning the ultrasonic catheter at the treatment site, such that at least a portion of the distal region is within the occlusion;
passing a therapeutic compound through the fluid delivery lumen such that the therapeutic compound is delivered to the treatment site; and
emitting ultrasonic energy from the ultrasound radiating member operating at a frequency of between 500 kHz and about 20 MHz, wherein the emitted ultrasonic energy hasan amplitude that is periodically varied between a low amplitude and a high amplitude,a pulse average power exclusive of the low amplitude periods of between approximately 0.01 watts and approximately 20 watts,a high amplitude pulse duration of between approximately 1 millisecond and approximately 50 milliseconds,a high amplitude pulse repetition rate of between approximately 5 hertz and approximately 150 hertz, andan in situ intensity at an energy radiating surface of between approximately 20 watts in−
2 and approximately 90 watts in−
2.
3 Assignments
0 Petitions
Accused Products
Abstract
A method of treating an occlusion at a treatment site within a patient'"'"'s vasculature comprises providing an ultrasonic catheter. The ultrasonic catheter has a distal region, a proximal region opposite the distal region, a fluid delivery lumen having at least one opening in the distal region, and an ultrasound radiating member positioned within the distal region. The method further comprises positioning the ultrasonic catheter at the treatment site, such that at least a portion of the distal region is within the occlusion. The ultrasonic catheter further comprises passing a therapeutic compound through the fluid delivery lumen such that the therapeutic compound is delivered to the treatment site. The ultrasonic catheter further comprises emitting ultrasonic energy from the ultrasound radiating member. The emitted ultrasonic energy has an amplitude that is periodically varied between a low amplitude and a high amplitude.
-
Citations
11 Claims
-
1. A method of treating an occlusion at a treatment site within a patient'"'"'s vasculature comprising:
-
providing an ultrasonic catheter having a distal region, a proximal region opposite the distal region, a fluid delivery lumen having at least one opening in the distal region, and an ultrasound radiating member positioned within the distal region; positioning the ultrasonic catheter at the treatment site, such that at least a portion of the distal region is within the occlusion; passing a therapeutic compound through the fluid delivery lumen such that the therapeutic compound is delivered to the treatment site; and emitting ultrasonic energy from the ultrasound radiating member operating at a frequency of between 500 kHz and about 20 MHz, wherein the emitted ultrasonic energy has an amplitude that is periodically varied between a low amplitude and a high amplitude, a pulse average power exclusive of the low amplitude periods of between approximately 0.01 watts and approximately 20 watts, a high amplitude pulse duration of between approximately 1 millisecond and approximately 50 milliseconds, a high amplitude pulse repetition rate of between approximately 5 hertz and approximately 150 hertz, and an in situ intensity at an energy radiating surface of between approximately 20 watts in−
2 and approximately 90 watts in−
2. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
-
Specification