Restoration of hearing loss
First Claim
1. A method of treating or ameliorating hearing loss, said method comprising administering a composition comprising nucleic acid that reduces inflammation,wherein said nucleic acid comprises a sequence encoding IL-10.
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Abstract
The present invention relates to compositions and methods for restoring hearing loss. In particular aspects, the invention relates to the administration of compositions that encode an inflammatory response control element. The compositions are prepared and administered in such a manner that the inflammatory response control element coding sequence is expressed in the subject to which the composition is administered. The compositions include expression systems, delivery systems, and certain inflammatory response control genes.
30 Citations
10 Claims
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1. A method of treating or ameliorating hearing loss, said method comprising administering a composition comprising nucleic acid that reduces inflammation,
wherein said nucleic acid comprises a sequence encoding IL-10.
Specification