Atrial retrograde management

• US 8,229,561 B2
• Filed: 12/15/2004
• Issued: 07/24/2012
• Est. Priority Date: 12/15/2004
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Zhang, Geng, Garg, Ankur
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): MALAMUD, DEBORAH LESLIE
• Application Number:
  US11/012,692
• Publication Number:
  US 20060129199A1
• Time in Patent Office: 2,778 Days
• Field of Search: None
• US Class Current: 607/28
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold
• CPC Class Codes: A61N 1/3714 Atrial capture

Abstract

Methods and systems for classifying cardiac responses to pacing stimulation and/or preventing retrograde cardiac conduction are described. Following delivery of a pacing pulse to an atrium of the patient'"'"'s heart during a cardiac cycle, the system senses in the atrium for a retrograde P-wave. The system classifies the atrial response to the pacing pulse based on detection of the retrograde P-wave. The system may also sense for an atrial evoked response and utilize the atrial evoked response in classifying the cardiac pacing response. If capture is not detected, the system may deliver additional atrial pacing pulses to reduce atrial retrograde conduction. A backup pace may be delivered to prevent the atrial retrograde conduction if an atrial evoked response is not detected during a cardiac cycle. Alternatively, retrograde management may involve delaying a next scheduled pace may be until expiration of an atrial effective refractory period.

Claims

1. An atrial retrograde management method, comprising:

delivering a pacing pulse to an atrium during a cardiac cycle;

determining if the atrial pacing pulse captured the atrium;

sensing for an intrinsic activation of the ventricle during the cardiac cycle;

delivering a pacing pulse to the ventricle if the intrinsic ventricular activation is not detected; and

providing atrial retrograde management if the atrial pacing pulse did not capture the atrium, the atrial retrograde management involving the delivery of another pacing pulse.

2. The method of claim 1, wherein determining if the atrial pacing pulse captured the atrium comprises:

sensing for an atrial evoked response; and

determining that the atrial pacing pulse did not capture the atrium if the atrial evoked response is not detected.

3. The method of claim 2, wherein providing the atrial retrograde management comprises delivering a backup pace to the atrium if the atrial evoked response is not detected.

4. The method of claim 1, wherein determining if the atrial pacing pulse captured the atrium comprises:

sensing in the atrium for a retrograde P-wave; and

determining that the atrial pacing pulse did not capture the atrium if the retrograde P-wave is detected.

5. The method of claim 4, wherein providing the atrial retrograde management comprises delaying a scheduled atrial pacing pulse for a subsequent cardiac cycle if the retrograde P-wave is sensed and if the scheduled atrial pacing pulse is scheduled to occur before expiration of an atrial effective refractory period timed relative to the retrograde P-wave.

6. The method of claim 5, further comprising increasing an energy of the delayed atrial pacing pulse beyond a previously scheduled energy.

7. The method of claim 5, further comprising modifying the effective refractory period if the delayed atrial pace does not produce capture.

8. The method of claim 5, further comprising delivering the scheduled atrial pacing pulse as scheduled if the scheduled atrial pace is not scheduled to occur before expiration of the atrial effective refractory period.

13. The method of claim 4, wherein providing the atrial retrograde management comprises delaying a scheduled atrial pacing pulse for a subsequent cardiac cycle if the retrograde P-wave is sensed.

14. The method of claim 4, wherein sensing for the retrograde P-wave comprises sensing for the retrograde P-wave during a post ventricular atrial refractory period.

15. The method of claim 4, wherein providing the atrial retrograde management comprises delivering a scheduled atrial pacing pulse for a subsequent cardiac cycle as scheduled if the retrograde P-wave is not sensed.

16. The method of claim 4, further comprising determining if a time between the retrograde P-wave and a next scheduled atrial pace is longer than an predetermined atrial effective refractory period.

17. The method of claim 1, wherein:

determining if the atrial pacing pulse captured the atrium comprises;

sensing for an atrial evoked response; and

sensing for a retrograde P-wave.

18. The method of claim 17, wherein providing atrial retrograde management comprises providing atrial retrograde management if the atrial evoked response is not sensed and the retrograde P-wave is sensed.

19. The method of claim 1, wherein:

delivering the pacing pulse to the atrium during the cardiac cycle comprises delivering the pacing pulse using a first electrode combination; and

determining if the atrial pacing pulse captured the atrium comprises sensing for an atrial evoked response using a second electrode combination other than the first electrode combination.

20. The method of claim 1, wherein determining if the atrial pacing pulse captured the atrium further comprises sensing for an retrograde P-wave using and electrode combination other than the second electrode combination.

9. An atrial retrograde management system, comprising:

means for delivering a pacing pulse to an atrium during a cardiac cycle;

means for determining if the atrial pacing pulse captured the atrium;

means for sensing for an intrinsic activation of the ventricle during the cardiac cycle;

means for delivering a pacing pulse to the ventricle if the intrinsic ventricular activation is not detected; and

means for delivering another pacing pulse to reduce atrial retrograde conduction if the atrial pacing pulse did not capture the atrium, the atrial retrograde conduction responsive to the ventricular pacing pulse or the intrinsic ventricular activation.

10. The system of claim 9, further comprising means for delaying a scheduled atrial pacing pulse for a subsequent cardiac cycle if the retrograde P-wave is sensed and if the scheduled atrial pacing pulse is scheduled to occur before expiration of an atrial effective refractory period timed relative to the retrograde P-wave.

11. The system of claim 10, further comprising means for modifying the effective refractory period if the delayed atrial pacing pulse does not produce capture.

12. The system of claim 10, further comprising means for delivering the scheduled atrial pacing pulse as scheduled if the scheduled atrial pacing pulse is not scheduled to occur before expiration of the atrial effective refractory period.