Sensor module for a catheter

• US 8,233,957 B2
• Filed: 01/11/2008
• Issued: 07/31/2012
• Est. Priority Date: 01/25/2007
• Status: Active Grant

• Current Assignee: NXP B.V. (NXP Semiconductors NV)
• Original Assignee: NXP B.V. (NXP Semiconductors NV)
• Inventors: Merz, Matthias, Ponomarev, Youri, Pijnenburg, Remco
• Primary Examiner(s): Natnithithadha, Navin
• Assistant Examiner(s): Reddy, Sunita
• Application Number:
  US12/523,512
• Publication Number:
  US 20100010327A1
• Time in Patent Office: 1,663 Days
• Field of Search: 600/345, 600/549, 600/547, 600/509, 600/372, 600302-308, 600346-371, 600481-507, 600529-545
• US Class Current: 600/345
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61M 2025/0002 with a pressure sensor at the distal end

Abstract

A sensor module (130) for a catheter (110), the sensor module (130) comprising a biofilm detection unit (131) adapted for detecting a characteristic of a biofilm (132) and electric circuitry (135, 800) for providing an output signal indicative of a result of the detection.

Claims

1. A catheter, the catheter comprising:

a tubular element enclosing a lumen;

a plurality of sensor modules spread out spatially along the length of the tubular element, wherein each of the sensor modules comprises;

a biofilm detection unit configured to detect a characteristic of a biofilm, wherein the biofilm detection unit includes a first sensor located at an inner surface of a tubular wall of the catheter and a second sensor located at an outer surface of the tubular wall of the catheter;

electric circuitry configured to provide an output signal indicative of a result of the detection,

wherein one of the sensor modules comprises a processing unit integrated in a tubular wall of the tubular element sandwiched between the first sensor and the second sensor, and wherein the plurality of sensor modules enable determination of a spatial dependence in the formation of the biofilm.

2. The catheter of claim 1,

wherein the processing unit is configured to process the characteristic for generating the output signal.

3. The catheter of claim 2,

wherein the processing unit is configured to generate a probability information regarding a reliability of the detected characteristic of the biofilm.

4. The catheter of claim 2,

wherein the processing unit is configured to generate the output signal continuously or at regular time intervals.

5. The catheter of claim 2,

wherein the processing unit is configured to generate the output signal comprising a unique identifier.

6. The catheter of claim 1,

wherein at least one biofilm detection unit comprises an ion sensitive field effect transistor.

7. The catheter of claim 1,

wherein at least one biofilm detection unit comprises an impedance sensor.

8. The catheter of claim 7,

wherein the impedance sensor is configured to perform a measurement between at least one first electrode integrated in a substrate and at least one second electrode integrated in the substrate or located in a medium surrounding the sensor module.

9. The catheter of claim 7,

wherein the impedance sensor is configured to perform a measurement between four electrodes arranged in a configuration with two outer electrodes and two inner electrodes arranged between the two outer electrodes;

wherein the impedance sensor is configured to apply an alternating electric signal between the outer electrodes and is configured to measure an electric response signal between the two inner electrodes indicative of the impedance value.

10. The catheter of claim 1,

comprising a communication unit configured to transmit, in a wired or wireless manner, the output signal to a base station.

11. The catheter of claim 1,

wherein at least a part of each sensor module is monolithically integrated in semiconductor technology.

12. The catheter of claim 1, wherein each of the sensor modules comprises a temperature detection unit configured to detect a temperature signal;

wherein the electric circuitry of the sensor module is configured to provide an output signal indicative of a result of the temperature detection.

13. The catheter of claim 1, wherein each sensor module comprises a memory configured to store data.

14. The catheter of claim 1,

further comprising a power supply unit configured to supply at least a part of the components of the plurality of sensor modules with electric energy, wherein the power supply unit comprises a rechargeable battery rechargeable in a wireless manner.

15. The catheter of claim 1, wherein each sensor module is configured to perform a bidirectional communication with an external programming unit for programming the sensor module.

16. The catheter of claim 1,

comprising a collection bag in fluid communication with the lumen of the tubular element.

17. The catheter of claim 1, wherein at least one biofilm detection unit is located at an outer surface of a tubular wall of the tubular element.

18. The catheter of claim 1,

wherein one of the sensor modules is configured to detect a characteristic of a biofilm formed in at least one of the group consisting of an intraluminal surface and an extraluminal surface of the tubular element.

19. The catheter of claim 1,

wherein at least a part of a surface of the catheter comprises an infection-inhibiting functionalization.

20. A base station, the base station comprising

a communication unit configured to communicate with a sensor module of claim 1;

an output unit configured to output the result of the detection of the sensor module.

21. The base station of claim 20,

comprising a programming unit configured to program the sensor module for bidirectional communication between the sensor module and the base station.

22. A method of operating a catheter, the method comprising:

detecting a characteristic of a biofilm using a plurality of sensor modules spread out spatially along the length of a tubular element of the catheter, wherein each of the sensor modules includes a first sensor located at an inner surface of a tubular wall of the catheter and a second sensor located at an outer surface of the tubular wall of the catheter, wherein one of the sensor modules comprises a processing unit integrated in a tubular wall of the tubular element sandwiched between the first sensor and the second sensor;

providing output signals indicative of a result of the detection; and

deriving spatially dependent biofilm formation information from the output signals using a processor.

23. A program element embodied in a non-transitory computer-readable medium, which, when being executed by a processor, is configured to control or carry out a method of claim 22 of operating a sensor module for a catheter.

24. A non-transitory computer-readable medium, in which a computer program is stored which, when being executed by a processor, is configured to control or carry out a method of claim 22 of operating a sensor module for a catheter.

25. A catheter, the catheter comprising

a tubular element enclosing a lumen;

a sensor module coupled to the tubular element, the sensor module comprising

a biofilm detection unit configured to detect a characteristic of a biofilm, wherein the biofilm detection unit includes an inner lumen electrode and an outer surface electrode for measuring impedance; and

electric circuitry configured to provide an output signal indicative of a result of the detection.