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System for transdermal chemical modulation of neural activity

  • US 8,233,976 B2
  • Filed: 06/18/2008
  • Issued: 07/31/2012
  • Est. Priority Date: 12/05/2007
  • Status: Active Grant
First Claim
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1. A neural modulation system comprising:

  • a signal input structure configured to receive a signal indicative of an activity state of at least a portion of a body of a subject innervated by a peripheral neural structure;

    a signal processing portion configured to;

    distinguish a low activity state of the at least a portion of the body of the subject innervated by the peripheral neural structure from a higher activity state of the at least a portion of the body of the subject innervated by the peripheral neural structure from the signal received at the signal input structure; and

    generate a chemical blocking agent control signal for driving delivery of a chemical blocking agent adapted to reversibly block conduction in the peripheral neural structure of the subject during at least a portion of the low activity state; and

    a chemical blocking agent source configured to be worn on the body of the subject and to deliver the chemical blocking agent responsive to the chemical blocking agent control signal.

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