Distributed anode cardiac pacing and sensing

• US 8,233,979 B1
• Filed: 03/21/2007
• Issued: 07/31/2012
• Est. Priority Date: 03/21/2007
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Shelchuk, Anne
• Primary Examiner(s): Lavert, Nicole F
• Application Number:
  US11/688,941
• Time in Patent Office: 1,959 Days
• Field of Search: 607/9, 607/119, 600/374, 600/393
• US Class Current: 607/9
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/3686 configured for selecting the electrode configuration on a lead A61N1/3688 takes precedence

Abstract

Embodiments of the present invention are directed to devices, systems and methods for pacing and sensing, in a chamber of a patient'"'"'s heart, that provide for good sensed R wave amplitudes and capture thresholds, yet avoids extracardiac stimulation. Such benefits are achieved by using what is referred to herein as a “distributed” anode, where one portion of the anode is within 5 mm of the cathode, but another portion of the anode is at least 10 mm from the cathode. While especially useful for pacing and sensing in the left ventricle, embodiments of the present invention can be used to pace and sense in any chamber of the heart.

Claims

1. A method for use when pacing and sensing in a chamber of a patient'"'"'s heart using a lead that includes a first group of at least two electrically isolated electrodes within 5 mm of one another and using a further electrode that is at least 10 mm from the first group, comprising:

(a) when pacing, using as a pacing cathode at least one of the electrodes of the first group;

(b) when pacing, using as a pacing anode at least one of the electrodes of the first group that is not used as the pacing cathode, together with the further electrode that is at least 10 mm from the first group also being used as the pacing anode;

(c) when sensing, using as the sensing cathode the same electrode(s) that is/are used as the pacing cathode when pacing at step (a); and

(d) when sensing, using as the sensing anode the same electrodes that are used as the pacing anode when pacing at step (b).

2. The method of claim 1, wherein the lead includes the further electrode.

3. The method of claim 2, wherein the further electrode comprises a ring electrode.

4. The method of claim 2, wherein the further electrode comprises a coil electrode.

5. The method of claim 2, wherein:

the lead includes first and second electrically isolated conductors;

one of the first group of electrodes is hardwired to the first conductor;

another one of the first group of electrodes is hardwired to the second conductor; and

the further electrode, which is at least 10 mm from the first group of electrodes, is also hardwired to the second conductor.

6. The method of claim 1, wherein the further electrode is an electrode of a further lead.

7. The method of claim 1, wherein the lead is connected to an implantable cardiac stimulation device having a conductive housing;

and

step (b) includes using as the pacing anode at least one of the electrodes of the first group that is not used as the pacing cathode, together with the conductive housing also being used as the pacing anode.

8. The method of claim 1, wherein the lead is configured such that the first group of electrodes can be placed in a patient'"'"'s left ventricle.

9. The method of claim 1, wherein the lead includes a second group of at least two electrically isolated electrodes within 5 mm of one another, which are at least 10 mm from the first group;

and

step (b) includes using as the pacing anode at least one of the electrodes of the first group that is not used as the pacing cathode, together with at least one of the electrodes of the second group also being used as the pacing anode.

10. The method of claim 9, wherein:

the lead includes first and second electrically isolated conductors;

each group of electrodes includes switching circuitry to selectively connect each electrode of the group to either of the conductors; and

step (a) includes connecting as the pacing cathode one of the electrodes of the first group; and

step (b) includes connecting as the pacing anode one of the electrodes of the first group that is not used as the pacing cathode, together with one of the electrodes of the second group also being connected as the pacing anode.

11. The method of claim 10, wherein:

step (a) includes configuring the switching circuitry of the first group to connect at least one of the electrodes of the first group to the first conductor; and

step (b) includes

configuring the switching circuitry of the first group to connect at least one of the other electrodes of the first group to the second conductor; and

configuring the switching circuitry of the second group to connect at least one of the electrodes of the second group to the second conductor.

12. An implantable cardiac stimulation system, comprising:

pacing circuitry;

sensing circuitry;

a lead that includes a first group of at least two electrically isolated electrodes within 5 mm of one another; and

a further electrode that is at least 10 mm from the first group;

wherein, during pacing,

a pacing cathode operably connected to the pacing circuitry includes at least one of the electrodes of the first group, and

a pacing anode operably connected to the pacing circuitry includes at least one of the electrodes of the first group that is not used as the pacing cathode, together with the further electrode that is at least 10 mm from the first group also operably connected to the pacing circuitry as the pacing anode; and

wherein, during sensing,

a sensing anode includes the same electrodes as the pacing anode that are instead operably connected to the sensing circuitry, and

a sensing cathode includes the same electrode(s) as the pacing cathode that is/are instead operably connected to the sensing circuitry.

13. The system of claim 12, wherein the lead includes the further electrode.

14. The system of claim 13, wherein the further electrode comprises a ring electrode.

15. The system of claim 13, wherein the further electrode comprises a coil electrode.

16. The system of claim 13, wherein:

the lead includes first and second electrically isolated conductors;

one of the first group of electrodes is hardwired to the first conductor;

another one of the first group of electrodes is hardwired to the second conductor; and

the further electrode, which is at least 10 mm from the first group of electrodes, is also hardwired to the second conductor.

17. The system of claim 12, further comprising:

a further lead;

wherein the further electrode is an electrode of the further lead.

18. The system of claim 12, further comprising:

a plurality of switches;

wherein the switches are configured to enable the pacing circuitry to pace in a chamber of the patient'"'"'s heart, and the sensing circuitry to sense in the chamber of the patient'"'"'s heart.

19. The system of claim 18, further comprising:

a conductive housing within which are located the pacing circuitry, the sensing circuitry, and the switches; and

the switches are configured to enable the pacing circuitry to pace in a chamber of the patient'"'"'s heart, and the sensing circuitry to sense in the chamber of the patient'"'"'s heart, using as the anode at least one of the electrodes of the first group together with the conductive housing.

20. The system of claim 12, wherein the lead is configured such that the first group of electrodes can be placed in a patient'"'"'s left ventricle.

21. The system of claim 18 wherein the lead includes a second group of at least two electrically isolated electrodes within 5 mm of one another, which are at least 10 mm from the first group;

and

the switches are configured to enable the pacing circuitry to pace in a chamber of the patient'"'"'s heart, and the sensing circuitry to sense in the chamber of the patient'"'"'s heart, using as the anode at least one of the electrodes of the first group that is not used as the cathode, together with at least one of the electrodes of the second group also being used as the anode.

22. The system of claim 21, wherein:

the lead includes first and second electrically isolated conductors;

each group of electrodes includes switching circuitry to selectively connect each electrode of the group to either of the conductors; and

wherein the switching circuitry of the first group is configured to connect at least one of the electrodes of the first group to the first conductor and at least one other electrode of the first group to the second conductor; and

wherein the switching circuitry of the second group is configured to connect at least one of the electrodes of the second group to the second conductor.

23. The system of claim 12, wherein, during sensing, the sensing cathode includes the at least one of the electrodes of the first group, and the sensing anode includes the at least one of the electrodes of the first group that is not used as the sensing cathode, together with the further electrode that is at least 10 mm from the first group also being used at the sensing anode.

24. A lead, comprising:

first and second electrically isolated conductors;

first and second electrically isolated electrodes within 5 mm of one another; and

a third electrode at least 10 mm from the first and second electrodes;

wherein the first electrode is hardwired to the second conductor for use as a cathode; and

wherein the second and third electrodes are hardwired to the first conductor for use as an anode at the same time.

25. The lead of claim 24, wherein there is always an electrical short between the second and the third electrode.