Device for non-invasively measuring glucose

• US 8,235,897 B2
• Filed: 04/20/2011
• Issued: 08/07/2012
• Est. Priority Date: 04/27/2010
• Status: Active Grant

• Current Assignee: A.D. Integrity Applications Ltd.
• Original Assignee: A.D. Integrity Applications Ltd.
• Inventors: Gal, Avner, Raykhman, Alexander M., Naidis, Eugene, Mayzel, Yulia, Klionsky, Alexander, Diber, Anatoly
• Primary Examiner(s): Natnithithadha, Navin
• Assistant Examiner(s): TOTH, KAREN E
• Application Number:
  US13/090,535
• Publication Number:
  US 20110263956A1
• Time in Patent Office: 475 Days
• Field of Search: 600/300, 600/347, 600/365
• US Class Current: 600/365
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/6816 Ear lobe

Abstract

In order to increase the accuracy of non-invasive glucose measurement, the device uses a combination of three non-invasive methods: ultrasonic, electromagnetic and thermal. The non-invasive glucose monitor comprises a Main Unit, which drives three different sensor channels (one per technology), located on an external unit configured as an ear clip attached to the subject'"'"'s ear lobe. To effect the ultrasonic channel, ultrasonic piezo elements are positioned on opposing portions of the ear clip and thus opposite sides of the ear lobe. For implementation of the electromagnetic channel, capacitor plates are positioned on opposing portions of the ear clip and the ear lobe serves as the dielectric. The thermal channel includes a heater and a sensor positioned on the ear clip in close juxtaposition to the ear lobe.

Claims

1. A device for non-invasively measuring glucose level in a subject comprising:

a unitary external unit having a first portion and an opposing second portion configured to receive a part of the subject'"'"'s body therebetween;

(a) a first ultrasonic piezo element positioned on the first portion and a second ultrasonic piezo element positioned on the opposing second portion of said external unit, a first membrane covering the first ultrasonic piezo element and a second membrane covering the second ultrasonic piezo element for measuring glucose levels utilizing ultrasonics;

(b) the first membrane and the second membrane constituting respective first and second capacitor plates with an auto-oscillating means connected thereto for measuring glucose levels utilizing electromagnetics; and

(c) a heater and a thermal sensor both positioned on the first portion and spaced from the first ultrasonic piezo element for measuring glucose level by thermal characteristics.

2. The device according to claim 1, wherein said ultrasonic piezo elements, said capacitor plates and said heater and said thermal sensor are contained within said external unit.

3. The device according to claim 2, further comprising a main unit for controlling measurements, receiving glucose level values from said external unit and calculating a weighted combination of said glucose level values to produce an accurate glucose reading;

and, means for electrically connecting said main unit and said external unit.

4. The device according to claim 3 wherein said ultrasonic piezo elements include a transducer and a receiver.

5. The device according to claim 2, wherein said external unit further comprises means for determining a distance between said first portion and said opposing second portion.

6. The device according to claim 5, wherein said means for determining comprises a magnet and a sensor.

7. The device according to claim 5, wherein said external unit further comprises an adjustment screw setting a distance between said first portion and said opposing second portion.

8. The device according to claim 2, wherein said external unit further includes an ambient temperature sensor.