Method and device for non-thermal electrically-induced closure of blood vessels by occlusion
First Claim
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1. A method of causing an occlusion of targeted blood vessels in a patient, the method comprising:
- contacting a tissue or skin surface of the patient with an electric probe, wherein the tissue or skin surface is proximate the targeted blood vessels; and
applying electric pulses to the tissue with the electric probe, the pulses each having a duration from about 0.01 μ
s to about 1 ms, wherein the targeted blood vessels have achieved a desired extent of irreversible occlusion with no thermal damage to the tissue, and wherein the targeted blood vessels have at least one of;
an aneurysm, an arteriovenous fistula, an internal bleeding site, traumatic damage, or a port wine stain.
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Abstract
Methods and devices for the non-thermal, electrically-induced temporary or permanent closure of blood vessels. Methods and devices employ pulsed electrical energy according to a defined regime to effect controlled occlusion of targeted blood vessels without heating the vessel and with minimal damage to adjacent tissue. The extent of vessel closure, i.e., temporary (vasoconstriction) or permanent (thrombosis), is controlled based on the manipulation of various parameters of the electrical stimulation regime as well as the configuration of the electrodes used to apply the regime.
31 Citations
18 Claims
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1. A method of causing an occlusion of targeted blood vessels in a patient, the method comprising:
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contacting a tissue or skin surface of the patient with an electric probe, wherein the tissue or skin surface is proximate the targeted blood vessels; and applying electric pulses to the tissue with the electric probe, the pulses each having a duration from about 0.01 μ
s to about 1 ms, wherein the targeted blood vessels have achieved a desired extent of irreversible occlusion with no thermal damage to the tissue, and wherein the targeted blood vessels have at least one of;
an aneurysm, an arteriovenous fistula, an internal bleeding site, traumatic damage, or a port wine stain. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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Specification