Bioerodible endoprosthesis
First Claim
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1. An endoprosthesis comprising a tubular member defined by a plurality of struts, at least one strut of the tubular member having a central longitudinal axis and including:
- (a) a central portion of the at least one strut that extends along the central longitudinal axis, the central portion lacking corrosion enhancing deposits;
(b) an underlying portion comprising a first bioerodible metal including a matrix and corrosion enhancing deposits within the matrix, the underlying portion extending radially outward from the central portion relative to the central longitudinal axis;
the underlying portion having a thickness of at least 1 micrometer;
(c) a surface portion having a thickness of between 0.1 micrometers and 3micrometers overlying and extending radially outward from the underlying portion relative to the central longitudinal axis, the surface portion comprising a second bioerodible metal having the composition of the matrix and being substantially free of corrosion enhancing deposits;
the surface portion having a first erosion rate and the underlying portion having a second erosion rate that is greater than the first erosion rate when the surface portion and the underlying portion are exposed to physiological environments.
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Abstract
An endoprosthesis can include a body including an underlying portion and a surface portion overlying the underlying portion. The underlying portion can include a bioerodible metal in the form of a matrix and corrosion enhancing deposits within the matrix. The surface portion including the bioerodible metal of the matrix. The surface portion having a first erosion rate when exposed to a physiological environment and the underlying portion having a second erosion rate when exposed to a physiological environment that is greater than the first erosion rate.
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Citations
13 Claims
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1. An endoprosthesis comprising a tubular member defined by a plurality of struts, at least one strut of the tubular member having a central longitudinal axis and including:
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(a) a central portion of the at least one strut that extends along the central longitudinal axis, the central portion lacking corrosion enhancing deposits; (b) an underlying portion comprising a first bioerodible metal including a matrix and corrosion enhancing deposits within the matrix, the underlying portion extending radially outward from the central portion relative to the central longitudinal axis;
the underlying portion having a thickness of at least 1 micrometer;(c) a surface portion having a thickness of between 0.1 micrometers and 3micrometers overlying and extending radially outward from the underlying portion relative to the central longitudinal axis, the surface portion comprising a second bioerodible metal having the composition of the matrix and being substantially free of corrosion enhancing deposits; the surface portion having a first erosion rate and the underlying portion having a second erosion rate that is greater than the first erosion rate when the surface portion and the underlying portion are exposed to physiological environments. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification