Microcontrolled electrocardiographic monitoring circuit with differential voltage encoding

• US 8,239,012 B2
• Filed: 10/08/2010
• Issued: 08/07/2012
• Est. Priority Date: 10/08/2010
• Status: Expired due to Fees

• Current Assignee: Zoll Medical Corporation (Asahi Kasei Corporation)
• Original Assignee: Cardiac Science Operating Company (Cardica Incorporated)
• Inventors: Felix, Jason, Bardy, Gust H.
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): LEE, YUN H
• Application Number:
  US12/901,460
• Publication Number:
  US 20120089039A1
• Time in Patent Office: 669 Days
• Field of Search: 600/509, 600/523
• US Class Current: 600/523
• CPC Class Codes: A61B 5/30 Input circuits therefor
• CPC Class Codes: A61B 5/308 for electrocardiography [ECG]
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/332 Portable devices specially adapted therefor
• CPC Class Codes: A61B 5/333 Recording apparatus specially adapted therefor
• CPC Class Codes: A61B 5/346 Analysis of electrocardiograms
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7232 involving compression of the physiological signal, e.g. to extend the signal recording period

Abstract

A microcontrolled electrocardiographic monitoring circuit with differential voltage encoding is provided. An input signal path includes an electrode, a low pass filter, and an amplifier, which are each connected in-line. The electrode senses an input signal via a conductive surface and the amplifier outputs a filtered amplified output signal. A microcontroller circuit includes an input codec, an analog-to-digital converter, and an encoder. The analog-to-digital converter is connected to the input signal path through an output of the amplifier and converts the filtered amplified output signal into a data stream of discrete digital values. The encoder determines a differential voltage between a current discrete digital value and a prior discrete digital value in the data stream. Persistent memory is connected to the microcontroller circuit via a peripheral serial interface bus, wherein the differential voltages for each of the discrete digital values in the data stream are stored into the persistent memory.

Claims

1. A microcontrolled electrocardiographic monitoring circuit with differential voltage encoding, comprising:

an input signal path comprising an electrode, a low pass filter, and an amplifier, each connected in-line, the electrode configured to sense an input signal via a conductive surface and the amplifier configured to output a filtered amplified output signal;

a microcontroller circuit comprising an input codec, comprising;

an analog-to-digital converter connected to the input signal path through an output of the amplifier and configured to convert the filtered amplified output signal into a data stream of discrete digital values; and

an encoder configured to determine a differential voltage between a current discrete digital value and a prior discrete digital value in the data stream; and

a feedback generator configured to identify a pairing of drive resistor settings matched to each discrete digital value in the data stream and output the drive resistor settings from the microcontroller circuit as a digital feedback signal through a pair of output terminals; and

persistent memory connected to the microcontroller circuit via a peripheral serial interface bus, wherein the differential voltages for each of the discrete digital values in the data stream are stored into the persistent memory;

an output signal path comprising an electrode and a buffer, each connected in-line, and a pair of drive resistors connected in parallel to an input terminal of the buffer and to the output terminals of the feedback generator, the microcontroller circuit configured to adjust each drive resistor according to the digital feedback signal, and the electrode configured to provide an output signal via a conductive surface.

2. A circuit according to claim 1, wherein the persistent memory is configured to store a set of enumerated ranges of voltage differences;

and

the microcontroller circuit further comprising a selector configured to assign an encoded value to each of the enumerated ranges, identify the enumerated range within which the differential voltage falls and select the encoded value corresponding to the identified enumerated range.

3. A circuit according to claim 1, the feedback generator further comprising:

a feedback marker configured to generate and store a feedback marker value into the persistent memory in sequence with the discrete digital values in the data stream.

4. A circuit according to claim 3, the microcontroller circuit further comprising:

a decoder configured to retrieve each of the differential voltages from the persistent memory and reproduce analog cardiac action potential signals from the retrieved differential voltages; and

an adjuster configured to determine a contribution from feedback from the feedback marker value and subtract the feedback contribution from the analog cardiac action potential signals.

5. A circuit according to claim 4, the microcontroller circuit further comprising:

a reference compensator configured to extend resolution of each discrete digital value as a function of the subtraction of feedback contribution before analog cardiac action potential signals reproduction.

6. A circuit according to claim 1, wherein each discrete digital value comprises a voltage representative of an analog cardiac action potential signal, further comprising:

a power supply, the microcontroller circuit configured to be powered by the power supply; and

the microcontroller circuit further comprising a reference compensator configured to determine the voltage of the power supply and normalize the voltage for each of the discrete digital values against depletion of the voltage of the power supply over a monitoring period.

7. A circuit according to claim 6, further comprising:

a reference scaler configured to scale the voltage of the power supply based on a number of write operations into the persistent memory and set the voltage for each of the discrete digital values based upon placement of the specific retrieved discrete digital value within an ordering of all of the retrieved discrete digital values.

8. A microcontrolled electrocardiographic monitoring circuit with discrete digital value encoding, comprising:

an input signal path comprising an electrode, a low pass filter, and an amplifier, each connected in-line, the electrode configured to sense an input signal via a conductive surface and the amplifier configured to output a filtered amplified output signal;

a power supply;

a microcontroller circuit configured to be powered by the power supply and comprising an input codec, comprising;

an analog-to-digital converter connected to the input signal path through an output of the amplifier and configured to convert the filtered amplified output signal into a data stream of discrete digital values, each discrete digital value comprising a voltage representative of an analog cardiac action potential signal;

an encoder configured to determine a differential voltage between a current discrete digital value and a prior discrete digital value in the data stream and select an encoded value representative of the differential voltage;

a reference compensator configured to determine a voltage for the power supply and normalize each of the discrete digital values against depletion of the voltage of the power supply over a monitoring period; and

persistent memory connected to the microcontroller circuit via a peripheral serial interface bus, wherein the encoded values for each of the differential voltages are stored into the persistent memory.

9. A circuit according to claim 8, wherein the persistent memory is configured to store a set of enumerated ranges of voltage differences that each correspond to lower and upper bounds of voltage;

and

the microcontroller circuit further comprising a selector configured to assign an encoded value is each of the enumerated ranges and identify the enumerated range within which the differential voltage falls by comparison of the differential voltage to the lower and upper bounds of voltage.

10. A circuit according to claim 8, the microcontroller circuit further comprising:

a decoder configured to retrieve each of the encoded values from the persistent memory and reproduce analog cardiac action potential signals from the retrieved encoded values.

11. A circuit according to claim 8, further comprising:

a reference scaler configured to scale the voltage of the power supply based on a number of write operations into the persistent memory and the voltage for each of the discrete digital values based upon placement of the specific retrieved discrete digital value within an ordering of all of the retrieved discrete digital values.