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Use of cardiac parameters in methods and systems for treating a chronic medical condition

  • US 8,239,028 B2
  • Filed: 04/24/2009
  • Issued: 08/07/2012
  • Est. Priority Date: 04/24/2009
  • Status: Active Grant
First Claim
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1. A method of adapting treatment of a patient having a chronic medical condition during periods of heightened stress on regulatory adaptation systems of the patient, comprising:

  • applying a first electrical signal to a neural structure of the patient to treat the chronic medical condition, the first electrical signal defined by a first set of signal parameter values;

    determining a time of beat sequence of the patient'"'"'s heart;

    determining a first index of activity of regulatory systems (IARS) value based on said time of beat sequence, the first IARS value indicative of a stress level of the regulatory adaptation systems of the patient;

    comparing the first IARS value to a first IARS threshold; and

    adjusting the first electrical signal to provide a second electrical signal to the neural structure of the patient in response to the first IARS value exceeding the first IARS threshold, the second electrical signal defined by a second set of signal parameter values, wherein at least one value of the second set of signal parameter values is different from a corresponding value in the first set of signal parameter values.

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