Biosensors and methods of preparing same
First Claim
1. A method of determining the concentration of an analyte in a sample, the method comprising:
- contacting the sample with a biosensor, wherein the biosensor comprises;
a spacer layer that provides a sample chamber between an electrode support and a cover, the sample chamber comprising a proximal end where the sample is introduced into the sample chamber and a distal end toward which the sample flows,wherein at least a portion of an electrode arrangement is located within the sample chamber, and wherein an incompressible element placed in-between said cover and said spacer layer provides at least one vent in the sample chamber, wherein the incompressible element is positioned only at the distal end of the sample chamber or only near the distal end of the sample chamber;
wherein said biosensor is configured to determine the concentration of an analyte in said sample.
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Accused Products
Abstract
A biosensor strip having a low profile for reducing the volume of liquid sample needed to perform an assay. In one embodiment, the biosensor strip includes an electrode support; an electrode arrangement on the electrode support; a cover; a sample chamber; and an incompressible element placed between the cover and the electrode support, the incompressible element providing an opening in at least one side or in the distal end of the sample chamber to provide at least one vent in the sample chamber. In another embodiment, the biosensor strip has an electrode support; an electrode arrangement on the electrode support; a cover; and a sample chamber, the cover having a plurality of openings formed therein, at least one of the openings in register with the sample chamber. The invention further includes methods for preparing such a biosensor strips in a continuous manner.
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Citations
23 Claims
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1. A method of determining the concentration of an analyte in a sample, the method comprising:
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contacting the sample with a biosensor, wherein the biosensor comprises; a spacer layer that provides a sample chamber between an electrode support and a cover, the sample chamber comprising a proximal end where the sample is introduced into the sample chamber and a distal end toward which the sample flows, wherein at least a portion of an electrode arrangement is located within the sample chamber, and wherein an incompressible element placed in-between said cover and said spacer layer provides at least one vent in the sample chamber, wherein the incompressible element is positioned only at the distal end of the sample chamber or only near the distal end of the sample chamber; wherein said biosensor is configured to determine the concentration of an analyte in said sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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Specification