Reactive surgical implant
First Claim
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1. A medical device comprising:
- a substrate in combination with a reactive component having at least one free reactive group, wherein the combination of the substrate and the reactive component create a reactive implant for chemically bonding the reactive implant with a tissue surface upon implantation, wherein the reactive component is present on the reactive implant in an amount of from about 0.05% by weight of the reactive implant to about 5% by weight of the reactive implant and wherein the reactive component is genipin.
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Abstract
Biocompatible implants including a polymer substrate and a reactive component for implant fixation in situ. The reactive component in combination with the substrate creates a reactive implant which bonds to a tissue surface in situ.
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Citations
11 Claims
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1. A medical device comprising:
a substrate in combination with a reactive component having at least one free reactive group, wherein the combination of the substrate and the reactive component create a reactive implant for chemically bonding the reactive implant with a tissue surface upon implantation, wherein the reactive component is present on the reactive implant in an amount of from about 0.05% by weight of the reactive implant to about 5% by weight of the reactive implant and wherein the reactive component is genipin. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A reactive implant comprising a porous substrate in combination with a reactive component, wherein the reactive component includes a first reactive group that chemically bonds the reactive component to the porous substrate and a second reactive group that crosslinks the porous substrate to at least one tissue surface, wherein the reactive component is present on the reactive implant in an amount of from about 0.001% by weight of the reactive implant to about 10% by weight of the reactive implant, and wherein the reactive component is genipin.
Specification