Optical measurement instrument for living body

• US 8,244,324 B2
• Filed: 11/16/2007
• Issued: 08/14/2012
• Est. Priority Date: 01/25/2007
• Status: Expired due to Fees

• Current Assignee: Hitachi, Ltd.
• Original Assignee: Hitachi, Ltd.
• Inventors: Atsumori, Hirokazu, Kiguchi, Masashi, Horita, Tadahiro
• Primary Examiner(s): Winakur, Eric
• Assistant Examiner(s): Liu, Chu Chuan (JJ)
• Application Number:
  US11/941,296
• Publication Number:
  US 20080183056A1
• Time in Patent Office: 1,733 Days
• Field of Search: 600/310, 600/316, 600/318, 600/322, 600/323, 600/324, 600/326, 600/340, 600/473, 600/476
• US Class Current: 600/310
• CPC Class Codes: A61B 2560/0252 using ambient temperature
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/7228 Signal modulation applied to the input signal sent to patient or subject; demodulation to recover the physiological signal modulation H03C
• CPC Class Codes: G01N 21/253 for batch operation, i.e. multisample apparatus analytical automats G01N35/00

Abstract

An optical measurement instrument for a living body having an optical fiber removed, which is composed so as to transmit a driving signal for the light source to a plurality of an irradiation parts, as well as to convert a transmitted and received signal, between a processing and control unit and the probe unit, to a row of serial digital signals, by having one driving device for light source and one multiplexer, inside the probe unit.

Claims

1. An optical measurement instrument for a living body, the optical measurement instrument comprising:

a probe unit including a plurality of light irradiation parts for irradiating light onto a subject, and a plurality of light detection parts for detecting light transmitting through or reflecting from the inside of said subject; and

a processing and control unit adapted to transmit a signal for light modulation on light to be emitted from each of said light irradiation parts to said probe unit, and to receive a measurement result corresponding with received light signals from said probe unit,

wherein said probe unit further comprises, inside thereof;

at least one driving device configured to receive said signal for light modulation and to output a driving signal which is modulated depending on said signal for light modulation and is to be sequentially distributed to each of said light irradiation parts;

a multiplexer for timewise and sequentially distributing said driving signal to each of said light irradiation parts to make each of said light irradiation parts sequentially emit light involving an intensity modulation;

a plurality of analog-to-digital converters respectively configured to convert respective light detection signals detected at said light detection parts into digital signals; and

a parallel-serial converter configured to convert the light detection signals that were respectively converted to the digital signals into a serial signal that is sequentially indicating each of light values respectively detected at said light detection parts and to transmit the serial signal to said processing and control unit as the measurement result.

2. The optical measurement instrument for the living body according to claim 1, wherein said probe unit further comprises, inside thereof:

a monitor photodiode in each of said light irradiation parts for monitoring intensity of light irradiated onto the subject at said each light irradiation part; and

another analog-to-digital converter configured to convert a monitoring signal emitted at said monitor photodiode in said each light irradiation part, from an analog signal to a digital signal;

wherein said monitoring signal is transmitted to said processing and control unit and said light detection signal that was transmitted from each of said light detection parts to said processing and control unit is divided by said monitoring signal emitted at said monitor photodiode in said each light irradiation part.

3. The optical measurement instrument for the living body according to claim 1, wherein said probe unit further comprises, inside thereof:

a monitor photodiode in each of said light irradiation parts for monitoring intensity of light irradiated onto the subject at said each light irradiation part; and

another analog-to-digital converter configured to convert a monitoring signal emitted at said monitor photodiode in said each light irradiation part, from an analog signal to a digital signal;

wherein intensity of light emitted at said each light irradiation part is maintained nearly constant, by transmitting said monitoring signal to said processing and control unit, and adjusting said signal for light modulation based on said monitoring signal emitted at said monitor photodiode in said each light irradiation part.

4. The optical measurement instrument for the living body according to claim 1, wherein said probe unit further comprises, inside thereof:

a plurality of multiplexers which are configured to receive said driving signal from said at least one driving device and to share burden to sequentially distribute said driving signal to said light irradiation parts.

5. The optical measurement instrument for the living body according to claim 1, wherein said probe unit further comprises, inside thereof:

a plurality of driving devices configured to output a plurality of driving signals and a plurality of multiplexers;

wherein signal for light modulation, each having different modulation frequencies or codes, are transmitted to each of a plurality of said driving devices, and said driving signals, which are respectively modulated depending on said signals for light modulation, each having different modulation frequencies or codes, are transmitted to each of said multiplexers.

6. An optical measurement instrument for a living body, the optical measurement instrument comprising:

a probe unit including a plurality of light irradiation parts for irradiating light onto a subject, and a plurality of light detection parts for detecting light transmitting through or reflecting from the inside of said subject; and

a processing and control unit adapted to transmit a signal for light modulation on light to be emitted from each of said light irradiation parts to said probe unit, and to receive a measurement result corresponding with received light signals from said probe unit;

wherein said probe unit further comprises, inside thereof;

at least one driving device configured to receive said signal for light modulation and to output a driving signal which is modulated depending on said signal for light modulation and is to be sequentially distributed to each of said light irradiation parts;

wherein light irradiated at each of said light irradiation parts is emitted independently timewise and subjected to intensity modulation, said measurement result is transmitted as a serial signal to said processing and control unit, and said processing and control unit is configured to perform a lock-in detection processing of the measurement result.

7. The optical measurement instrument for the living body according to claim 6, wherein said probe unit further comprises, inside thereof:

a multiplexer for timewise and sequentially distributing said driving signal to each of said light irradiation parts to make each of said light irradiation parts sequentially emit light involving an intensity modulation;

a plurality of analog-to-digital converters respectively configured to convert respective light detection signals detected at said light detection parts into digital signals; and

a parallel-serial converter configured to convert the light detection signals that were respectively converted to the digital signals into said serial signal that is sequentially indicating each of light values respectively detected at said light detection parts result.

8. The optical measurement instrument for the living body according to claim 7, wherein said probe unit further comprises, inside thereof:

a monitor photodiode in each of said light irradiation parts for monitoring intensity of light irradiated onto the subject at said each light irradiation part; and

another analog-to-digital converter configured to convert a monitoring signal emitted at said monitor photodiode in said each light irradiation part, from an analog signal to a digital signal;

wherein said monitoring signal is transmitted to said processing and control unit and said light detection signal that was transmitted from each of said light detection parts to said processing and control unit is divided by said monitoring signal emitted at said monitor photodiode in said each light irradiation part.

9. The optical measurement instrument for the living body according to claim 7, wherein said probe unit further comprises, inside thereof:

a monitor photodiode in each of said light irradiation parts for monitoring intensity of light irradiated onto the subject at said each light irradiation part; and

another analog-to-digital converter configured to convert a monitoring signal emitted at said monitor photodiode in said each light irradiation part, from an analog signal to a digital signal;

wherein intensity of light emitted at said each light irradiation part is maintained nearly constant, by transmitting said monitoring signal to said processing and control unit, and adjusting said signal for light modulation based on said monitoring signal emitted at said monitor photodiode in said each light irradiation part.

10. The optical measurement instrument for the living body according to claim 7, wherein said probe unit further comprises, inside thereof:

a plurality of multiplexers which are configured to receive said driving signal from said at least one driving device and to share burden to sequentially distribute said driving signal to said light irradiation parts.

11. The optical measurement instrument for the living body according to claim 7, wherein said probe unit further comprises, inside thereof:

a plurality of driving devices configured to output a plurality of driving signals and a plurality of multiplexers;

wherein signal for light modulation, each having different modulation frequencies or codes, are transmitted to each of a plurality of said driving devices, and said driving signals, which are respectively modulated depending on said signals for light modulation, each having different modulation frequencies or codes, are transmitted to each of said multiplexers.