Coronary sinus lead for pacing the left atrium

• US 8,244,376 B2
• Filed: 11/12/2009
• Issued: 08/14/2012
• Est. Priority Date: 06/03/2005
• Status: Active Grant

• Current Assignee: Oscor Inc
• Original Assignee: Oscor Inc
• Inventors: Worley, Seth
• Primary Examiner(s): Patel, Niketa
• Assistant Examiner(s): ALTER, ALYSSA MARGO
• Application Number:
  US12/590,689
• Publication Number:
  US 20100137965A1
• Time in Patent Office: 1,006 Days
• Field of Search: 607/125, 607/9, 607/126
• US Class Current: 607/125
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/057 Anchoring means; Means for fixing the head inside the heart
• CPC Class Codes: A61N 2001/0585 Coronary sinus electrodes

Abstract

A method of inserting a pacing lead having a preformed shape into a coronary sinus to pace the left atrium includes providing a lead having an elongated body and proximal and tip sections. The sections are configured such that a first angle less than 90 degrees is defined between the lead body and proximal section and a second angle is defined between the tip and proximal sections. The method further comprises advancing the pacing wire towards the opening of the coronary sinus and advancing the wire into the coronary sinus, such that the first angle is compressed by the coronary sinus opening and a tip electrode included on the tip section contacts the wall of the coronary sinus near the left atrium operably extending the second angle to assure constant contact between the wall of the coronary sinus and the tip electrode.

Claims

1. A pacing lead configured for implantation in a coronary sinus having an opening and a wall defining an interior, the pacing lead comprising:

a substantially straight elongated lead body defining an elongated longitudinal axis extending from a proximal end of the pacing lead to a first bend defined at a distal end thereof;

a proximal section extending from the first bend and terminating at a second bend defined at a distal end thereof, such that a first inside angle less than 90 degrees is defined between the lead body and proximal section;

a tip section having a tip axis extending therethrough and a tip electrode disposed thereon, the tip section extending from the second bend, such that a second inside angle is defined between the tip and proximal sections, wherein the pacing lead is configured such that when at least a portion of the first bend is inserted into the opening of the coronary sinus, the first inside angle is operably compressed by the coronary sinus opening and the tip electrode contacts the wall of the coronary sinus adjacent the lead body whereby the tip axis intersects elongated longitudinal axis of the elongated lead body.

2. The lead of claim 1, further comprising at least one secondary electrode disposed on at least a portion of the lead.

3. The lead of claim 2, wherein the secondary electrode is disposed on the proximal section.

4. The lead of claim 2, wherein the secondary electrode is disposed on the tip section.

5. The lead of claim 1, wherein the first inside angle defined between the lead body and proximal section is less than 45 degrees.

6. The lead of claim 1, wherein the second inside angle defined between the tip and proximal sections is between 90 and 150 degrees.

7. The lead of claim 1, further comprising a stylet disposed therein for selectively maintaining the stiffness of the lead as the lead is inserted into the opening of the coronary sinus.

8. The lead of claim 1, further comprising a catheter and a guidewire operably coupled to the catheter for guiding the lead towards the opening of the coronary sinus.

9. The lead of claim 1, wherein the lead comprises a lead width, the lead width being between 4 and 6 French.

10. A method of inserting a pacing lead having a preformed shape into a coronary sinus to pace a left atrium, the coronary sinus having an opening and a wall defining an interior, the method comprising:

providing a pacing lead comprising a substantially straight lead body having an elongated longitudinal axis extending from a proximal end of the pacing lead to a first bend defined at a distal end thereof, a proximal section extending from the first bend and terminating at a second bend defined at a distal end thereof, such that a first inside angle less than 90 degrees is defined between the lead body and proximal section, and a tip section having a tip electrode disposed thereon, the tip section having a tip axis extending from the second bend, such that a second angle is defined between the tip and proximal sections;

advancing the pacing lead towards the coronary sinus opening; and

advancing the first bend into the coronary sinus, such that the first inside angle is operably compressed by the coronary sinus opening and the pacing lead folds over and the tip electrode contacts the wall of the coronary sinus adjacent the lead body and proximate the left atrium whereby the tip axis intersects the elongated longitudinal axis of the lead body.

11. The method of claim 10, further comprising:

defining the first inside angle between the lead body and proximal section to be less than 45 degrees; and

advancing the first curve into the coronary sinus, such that the first inside angle is operably compressed to less than 45 degrees by the wall of the coronary sinus.

12. The method of claim 10, further comprising:

defining the second inside angle defined between the tip and proximal sections to be between 90 and 150 degrees; and

advancing the first curve into the coronary sinus, such that the second angle is operably extended to greater than 120 degrees by the wall of the coronary sinus.

13. The method of claim 10, further comprising advancing the first curve into the coronary sinus, such that the tip electrode is in substantially constant contact with the wall of the coronary sinus proximate the left atrium.

14. The method of claim 10, further comprising:

providing at least one secondary electrode disposed on a portion of the pacing lead; and

advancing the first curve into the coronary sinus, such that the secondary electrode is in substantially constant contact with at least a portion of the wall of the coronary sinus.

15. The method of claim 10, further comprising:

providing a guide catheter having a guide wire operably coupled thereto for guiding the pacing wire towards the coronary sinus opening;

anchoring the guide wire into at least a portion of the coronary sinus;

providing a stylet and inserting the stylet into the pacing wire having the preformed shape until the pacing wire comprises a substantially linear shape;

inserting the pacing wire having the substantially linear shape into the guide catheter;

advancing the guide catheter and pacing wire to a position proximate the opening of the coronary sinus; and

withdrawing the stylet out of the pacing wire to a position proximate the first bend;

advancing the pacing wire out of the sheath towards the opening of the coronary sinus, such that the pacing lead comprises the preformed shape prior to advancing the first curve into the coronary sinus.

16. A pacing lead configured for implantation in a coronary sinus having an opening and a wall defining an interior, the pacing lead comprising:

an elongated lead body having a body axis extending therethrough and a first bend defined thereon;

a proximal section having a second bend defined thereon, the proximal section extending from the first bend and defined between the first and second bends, such that a first inside angle less than 90 degrees is defined between the lead body and proximal section;

a tip section having a tip axis extending therethrough and a tip electrode disposed thereon, the tip section extending from the second bend, such that a second inside angle is defined between the tip and proximal sections, wherein the pacing lead is configured such that when at least a portion of the first bend is inserted into the opening of the coronary sinus, the first inside angle is operably compressed by the coronary sinus opening and the tip electrode contacts the wall of the coronary sinus, wherein when the first bend is inserted into the opening of the coronary sinus, the tip axis intersects the body axis when the tip and body axes are projected onto a common plane parallel to and including the body axis.

17. The lead of claim 16, wherein the first inside angle defined between the lead body and proximal section is less than 45 degrees.

18. The lead of claim 16, wherein the second inside angle defined between the tip and proximal sections is between 90 and 150 degrees.

19. The lead of claim 16, further comprising a stylet disposed therein for selectively maintaining the stiffness of the lead as the lead is inserted into the opening of the coronary sinus.

20. The lead of claim 16, wherein the lead comprises a lead width, the lead width being between 4 and 6 French.