State space model of a heart

• US 8,244,510 B2
• Filed: 07/06/2007
• Issued: 08/14/2012
• Est. Priority Date: 07/25/2006
• Status: Expired due to Fees

• Current Assignee: Gripping Heart AB
• Original Assignee: Gripping Heart AB
• Inventors: Lundbäck, Stig, Johnson, Jonas
• Primary Examiner(s): SMITH, CAROLYN L
• Application Number:
  US12/375,035
• Publication Number:
  US 20090311656A1
• Time in Patent Office: 1,866 Days
• Field of Search: None
• US Class Current: 703/11
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders

Abstract

A state space model (SSM), being a computer-calculated model, adapted to represent the pumping and controlling functions of a heart that have been determined by a heart cluster state machine simulating the heart, and optionally the circulatory system, of an individual. The state space model includes two groups of separate interacting state machines, the heart muscle cell state machines and the displacement pump state machines.

Claims

1. A state space model (SSM), being a computer-calculated model, adapted to represent pumping and controlling functions of a heart that have been determined by a heart cluster state machine simulating the heart of an individual and optionally the circulatory system of an individual,

wherein,

the state space model is adapted to transform all muscular cell functions, except their volumes, to incomplete and/or complete wire frames and/or surface mesh models of the heart and optionally the circulatory system with impacts of boundary conditions concerning the model, and

the state space model comprises two groups of separate interacting state machines, (1) heart muscle cell state machines and (2) DeltaV-pump state machines,

the heart muscle cell state machines comprising a main module describing construction and boundary conditions of a working cardiac muscle cell and their interrelations on a molecular level, with an internal module, leaving muscle cell volumes outside, describing cardiac muscle cell functions including a conducting system as construction material and power source with possibilities to be reluctant by elongation, firm by static work and create dynamic work by shortening, to be transferred to the contours and areas determined by the DeltaV-pump state machines.

2. The state space model according to claim 1, wherein the DeltaV-pump state machines comprise a main module divided into sub-modules schematically showing a construction of the heart as a geometric description of the heart in two and/or three dimensions as a mechanical device made by a fusion of two Delta-pump state machines, creating the right and left side of the heart.

3. The state space model according to claim 2, wherein the DeltaV-pump state machines further comprise:

an Intra Ventricular Septum module (IVS) describing constructions and functions of Intra Ventricular Septum as a result of the fusion of the two DeltaV-pump state machines generating a third DeltaV-pump state machine;

a Delta-V piston (DVP) module describing a construction and function of the Delta-V piston;

a RA-LA construction module describing construction and functions of the right and left atria and auricle constructions; and

a displacement pump state machine module consisting of lines, wire frames and/or surface mesh of outer contours and optionally inner contours of the muscle volumes in one, two or three dimensions.

4. The state space model according to claim 1, wherein the SSM is analyzed by a Heart State Analyzer (HSA) that presents the data as discrete and/or dynamic state diagrams, optionally handled and organized by an Interconnecting Management System (IMS).

5. The state space model according to claim 4, wherein a Graphical User Interface (GUI) module graphically presents one or several interacting discrete and/or dynamic time correlated state diagrams, optionally handled and organized by an Interconnecting Management System (IMS), obtained by the HSA describing the pumping and regulating functions of the heart and optionally the circulatory system.

6. The state space model according to claim 1, wherein an Efficiency Rate Analyzer (ERA) module is connected to the SSM, optionally handled and organized by an Interconnecting Management System (IMS), to compare an outcome of the mechanical functions of the heart with the heart muscular rearrangements obtained by the SSM, the ERA configured to present and optionally enhance an efficient rate of the muscles as construction material and power source.

7. The state space model according to claim 1, wherein a Heart State Simulator (HSS) is connected to the SSM for learning purposes and to simulate impacts that different kinds of boundary conditions changes will have on the modules of the SSM, optionally handled and organized by an Interconnecting Management System (IMS).

8. The state space model according to claim 5, wherein the SSM is arranged in an investigating device, a pressure sensor, a microphone, a photo sensor or a oxymeter, and includes HSA and GUI, to create discrete and/or dynamic time related state diagrams.

9. The state space model according to claim 4, wherein the model creates investigating methods in one, two and/or three dimensions by mapping interacting points, contours and/or areas correlated to the pumping and regulating functions of the heart by dynamic triangular measurements calculated by HSA according to the SSM, optionally handled and organized by an Interconnecting Management System (IMS).

10. The state space model according to claim 5, wherein the Graphical User Interface (GUI) module graphically presents one or several interacting discrete and/or dynamic time correlated state diagrams, optionally handled and organized by an Interconnecting Management System (IMS), obtained by (HSA) describing the pumping and regulating functions of the heart and optionally the circulatory system.