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Method of molding a microneedle

  • US 8,246,893 B2
  • Filed: 03/16/2011
  • Issued: 08/21/2012
  • Est. Priority Date: 12/07/2004
  • Status: Active Grant
First Claim
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1. A method of molding a microneedle array comprising:

  • (i) providing a mold apparatus comprising;

    a mold insert having the negative image of at least one microneedle;

    a compression core; and

    a mold housing configured to allow a reciprocal motion between the mold insert and the compression core,wherein the mold apparatus has an open position and a closed position;

    (ii) placing the mold apparatus in the closed position;

    (iii) applying acoustic energy having a frequency greater than about 5,000 Hz to the mold apparatus;

    (iv) injecting polymeric material into the closed mold apparatus;

    (v) compressing the injected polymeric material between the mold insert and the compression core by a reciprocal motion between the compression core and the mold insert;

    (vi) opening the mold; and

    (vii) removing the molded microneedle from the mold.

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