×

Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells

  • US 8,246,995 B2
  • Filed: 05/09/2006
  • Issued: 08/21/2012
  • Est. Priority Date: 05/10/2005
  • Status: Expired due to Fees
First Claim
Patent Images

1. A stable aqueous suspension of nanotube complexes suitable for delivery of a nanotube complex in said suspension to a living cell, said complex comprising:

  • (a) an individual carbon nanotube; and

    (b) a biologically active molecule, wherein said biologically active molecule comprises a polynucleic acid or a polypeptide bound to a linking agent which is noncovalently bound to the carbon nanotube, whereby the complex may be disassociated to release the biologically active molecule in active form inside a cell; and

    further comprising(c) said linking agent comprising (i) a hydrophilic polymer and (ii) a hydrophobic polymer linked to the hydrophilic polymer, said hydrophilic polymer being covalently bound to the biologically active molecule.

View all claims
  • 2 Assignments
Timeline View
Assignment View
    ×
    ×