Laser tissue fusion of septal membranes

• US 8,251,983 B2
• Filed: 05/14/2008
• Issued: 08/28/2012
• Est. Priority Date: 05/14/2007
• Status: Active Grant

• Current Assignee: The Board of Regents of the University of Colorado (University of Colorado System)
• Original Assignee: The Board of Regents of the University of Colorado (University of Colorado System)
• Inventors: Larson, Michael, McClure, Jesse, Hooper, Luke
• Primary Examiner(s): Park, Kinam
• Application Number:
  US12/600,087
• Publication Number:
  US 20100249763A1
• Time in Patent Office: 1,567 Days
• Field of Search: 606/8, 606/2, 607/89, 607/88
• US Class Current: 606/8
• CPC Class Codes: A61B 18/22 the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
• CPC Class Codes: A61B 2018/00327 Ear, nose or throat
• CPC Class Codes: A61B 2018/00619 Welding
• CPC Class Codes: A61B 2018/00982 combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes
• CPC Class Codes: A61B 2090/065 for measuring contact or contact pressure

Abstract

A laser tissue fusion device is optimized for particular surgical applications to join tissue layers. The device has two opposed arms that engage and disengage to clamp and release layers of tissue therebetween. The distal end of the first arm is disposed opposite the distal end of the second arm. A laser energy source generates therapeutic laser energy is either integrated within the device is a separate unit. An energy pathway transmits the laser energy to the distal end of the first arm to deliver the laser energy to tissue layers clamped between the distal ends of the arms. An actuator decreases the separation distance between the distal ends of the arms to clamp the tissue layers and activates the laser energy source upon engagement. The laser energy source delivers a burst of energy at a predetermined wavelength for a predetermined period of time sufficient to spot weld the tissue.

Claims

1. A device for laser fusion of biological tissue comprising

a first arm with a distal end;

a second arm with a distal end, wherein the distal end of the second arm is disposed opposite the distal end of the first arm;

a laser energy source that generates therapeutic laser energy;

an energy pathway that transmits the therapeutic laser energy from the laser energy source to the distal end of the first arm to deliver the therapeutic laser energy to layers of tissue of a patient positioned between the distal end of the first arm and the distal end of the second arm; and

an actuator configured to decrease a separation distance between the distal end of the first arm and the distal end of the second arm and further configured to activate the laser energy source.

2. The device of claim 1, wherein the actuator is further configured to deactivate the laser energy source.

3. The device of claim 1, wherein the energy pathway further comprises an optical fiber connected to the laser energy source.

4. The device of claim 1, wherein the distal end of the first arm comprises a reflector within the energy pathway to direct the therapeutic laser energy from the energy pathway to the layers of tissue.

5. The device of claim 1, wherein the distal end of the second arm further comprises a reflective surface positioned to reflect any of the therapeutic laser energy that travels through the tissue layers back into the tissue layers.

6. The device of claim 1, wherein

the distal end of the first arm is static;

and

the distal end of the second arm is motile.

7. The device of claim 1 further comprising

a handle portion connected to the first arm and the second arm, and wherein

the laser energy source is positioned within the handle portion.

8. The device of claim 1 further comprising

a handle portion connected to the first arm and the second arm and housing the actuator;

a cable connected between the actuator and the laser energy source to transmit control instructions from the actuator to the laser energy source, wherein the laser energy source is positioned external to the handle portion.

9. The device of claim 1, wherein, upon actuation of the actuator, the distal ends of the first arm and the second arm apply pressure to the layers of tissue.

10. A device for laser septal fusion comprising

a first arm with a distal end configured for insertion into a first nostril of a patient;

a second arm with a distal end configured for insertion into a second nostril of a patient, wherein the distal end of the second arm is disposed opposite the distal end of the first arm;

a laser energy source that generates therapeutic laser energy;

an energy pathway that transmits the therapeutic laser energy from the laser energy source to the distal end of the first arm to deliver the therapeutic laser energy to septal tissue between the nostrils of the patient; and

an actuator configured to decrease a separation distance between the distal end of the first arm and the distal end of the second arm and further configured to activate the laser energy source.

11. The device of claim 10, wherein the actuator is further configured to deactivate the laser energy source.

12. The device of claim 10, wherein the energy pathway further comprises an optical fiber connected to the laser energy source.

13. The device of claim 10, wherein the distal end of the first arm comprises a reflector within the energy pathway to direct the therapeutic laser energy from the energy pathway to the layers of tissue.

14. The device of claim 10, wherein the distal end of the second arm further comprises a reflective surface positioned to reflect any of the therapeutic laser energy that travels through the tissue layers back into the tissue layers.

15. The device of claim 10, wherein

the distal end of the first arm is static;

and

the distal end of the second arm is motile.

16. The device of claim 10 further comprising

a handle portion connected to the first arm and the second arm, and wherein

the laser energy source is positioned within the handle portion.

17. The device of claim 10 further comprising

a handle portion connected to the first arm and the second arm and housing the actuator;

a cable connected between the actuator and the laser energy source to transmit control instructions from the actuator to the laser energy source, wherein the laser energy source is positioned external to the handle portion.

18. The device of claim 10, wherein, upon actuation of the actuator, the distal ends of the first arm and the second arm apply pressure to the layers of tissue.

19. A method performing coaptation of nasal septal tissue comprising

pressing septal tissue together from opposite sides accessed through the nostrils of a patient;

applying therapeutic laser energy to the septal tissue for a period of time sufficient to fuse the septal tissue; and

releasing the pressure on the septal tissue.

20. The method of claim 19, wherein the applying operation further comprises applying the therapeutic laser energy to multiple small areas of the septal tissue.

21. A device for endoscopic laser tissue fusion comprising

a endoscopic tube;

a first jaw positioned at a distal end of the endoscopic tube;

a second jaw positioned at the distal end of the endoscopic tube and disposed opposite the first jaw;

a laser energy source that generates therapeutic laser energy;

an energy pathway that transmits the therapeutic laser energy from the laser energy source to the first jaw to deliver the therapeutic laser energy to layers of tissue of a patient positioned between the first jaw and the second jaw; and

an actuator configured to decrease a separation distance between a distal end of the first jaw and a distal end of the second jaw and further configured to activate the laser energy source.

22. The device of claim 21, wherein the actuator is further configured to deactivate the laser energy source.

23. The device of claim 21, wherein the energy pathway further comprises an optical fiber connected to the laser energy source.

24. The device of claim 21, wherein a distal end of the first jaw comprises a reflector within the energy pathway to direct the therapeutic laser energy from the energy pathway to the layers of tissue.

25. The device of claim 21, wherein a distal end of the second jaw further comprises a reflective surface positioned to reflect any of the therapeutic laser energy that travels through the tissue layers back into the tissue layers.

26. The device of claim 21, wherein

the first jaw is static;

and

the second jaw is motile.

27. The device of claim 26 further comprising

a tension cable connected at a first end to the actuator and at a second end to the second jaw and which is placed under tension upon actuation of the actuator;

and wherein

the second jaw further comprises a pivot structure fixed with respect to the endoscopic tube and about which the second jaw rotates when the tension cable is placed under tension to decrease the separation distance between the first jaw and the second jaw.

28. The device of claim 21 further comprising

a handle portion connected to the endoscopic tube, and wherein

the laser energy source is positioned within the handle portion.

29. The device of claim 21 further comprising

a handle portion connected to the endoscopic tube and housing the actuator;

a cable connected between the actuator and the laser energy source to transmit control instructions from the actuator to the laser energy source, wherein the laser energy source is positioned external to the handle portion.

30. The device of claim 21, wherein, upon actuation of the actuator, the distal ends of the first jaw and the second jaw apply pressure to the layers of tissue.