Process for the preparation of 6-(aryl)-4-aminopicolinates

• US 8,252,938 B2
• Filed: 06/07/2010
• Issued: 08/28/2012
• Est. Priority Date: 06/08/2009
• Status: Expired due to Fees

• Current Assignee: Dow Agrosciences LLC (Corteva, Inc.)
• Original Assignee: Dow Agrosciences LLC (Corteva, Inc.)
• Inventors: Renga, James M., Whiteker, Gregory T., Arndt, Kim E., Lowe, Christian T.
• Primary Examiner(s): Davis, Zinna Northington
• Application Number:
  US12/795,184
• Publication Number:
  US 20100311981A1
• Time in Patent Office: 813 Days
• Field of Search: None
• US Class Current: 546/310
• CPC Class Codes: C07D 211/90 Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
• CPC Class Codes: C07D 213/79 Acids; Esters

Abstract

3-Halo-6-(aryl)-4-iminotetrahydropicolinic acid esters are heated with polar solvents to prepare 6-(aryl)-4-aminopicolinates.

Claims

1. A process for the preparation of a 6-(aryl)-4-aminopicolinate of the formula

2. The process of claim 1 in which the polar solvent is a C₁-C₄ alkanoic acid.

3. The process of claim 1 in which the 3-halo-6-(aryl)-4-iminotetrahydropicolinic acid ester is prepared by chlorinating or brominating a sulfonylated, acylated or carbonate-containing oxime of the formula