Expandable stent

• US 8,257,427 B2
• Filed: 06/10/2009
• Issued: 09/04/2012
• Est. Priority Date: 09/11/2001
• Status: Active Grant

• Current Assignee: JW Medical Systems Ltd
• Original Assignee: JW Medical Systems Ltd
• Inventors: Andersen, Erik, Wen, Ning
• Primary Examiner(s): Jackson, Gary
• Assistant Examiner(s): BACHMAN, LINDSEY MICHELE
• Application Number:
  US12/481,792
• Publication Number:
  US 20090248137A1
• Time in Patent Office: 1,182 Days
• Field of Search: 623 115- 154
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/852 Two or more distinct overlapping stents
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/826 more than one stent being applied sequentially
• CPC Class Codes: A61F 2002/828 Means for connecting a plurality of stents allowing flexibility of the whole structure
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91525 within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2002/91591 Locking connectors, e.g. using male-female connections
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2250/0063 Nested prosthetic parts
• CPC Class Codes: A61F 2250/0068 the pharmaceutical product being in a reservoir

Abstract

An expandable stent comprising a tubular body made up of a plurality of separated tubular elements (1) arranged along a common longitudinal axis. Each tubular element (1) comprises a plurality of rhombic-shaped closed cell elements (2) joined by circumferentially extending linking members (3). The closed cell elements (2) are expandable to allow the tubular elements, and hence the stent itself, to expand. In the direction of the longitudinal axis of the stent, the extremities of each of the closed cell elements has an enlarged loop (30) with waisted portions (33) which allow the tubular elements to interlock to create a stable structure, at least when in the unexpanded condition.

Claims

1. A stent comprising:

a tubular body made up of a plurality of separate, radially expandable, tubular elements aligned along a common longitudinal axis, each tubular element being physically unconnected to any other tubular element when the tubular elements are radially expanded,

wherein at least some of the tubular elements each comprise a plurality of closed cell elements, each closed cell element joined to a circumferentially-adjacent closed cell element by a circumferentially-extending linking member, each circumferentially-extending linking member being attached to two circumferentially-neighboring closed cell elements at respective spaced apart attachment points,

wherein each closed-cell element comprises a pair of side members narrowing inwardly towards a side hinge to form a waist portion,

wherein at least some of the closed cell elements comprise an inter-engaging element engageable with a corresponding inter-engaging element on an adjacent tubular element holding the adjacent tubular elements together when engaged, at least in an unexpanded condition of the stent,

wherein the inter-engaging element comprises the pair of side members narrowing inwardly towards side hinge forming the waist portion such that two waist portions on circumferentially adjacent closed cell elements act together to retain the corresponding inter-engaging element on the adjacent tubular element;

wherein corresponding inter-engaging elements are movable relative to each other along the longitudinal axis when engaged allowing longitudinal movement between adjacent interlocked adjacent tubular elements so as to allow for increased flexibility of the stent in the unexpanded configuration and reduce shortening of the stent during expansion.

2. A stent as claimed in claim 1 wherein the tubular elements are also compressible.

3. A stent as claimed in claim 1 wherein each closed cell element is expandable in the circumferential direction of the tubular element, thus allowing the tubular element to expand and contract.

4. A stent as claimed in claim 3 wherein each closed cell element is positioned symmetrically with respect to the circumferential linking members.

5. A stent as claimed in claim 3 wherein each closed cell element comprises two attachment points, each of which joins to a respective circumferential linking member, and wherein the closed cell element is capable of expanding from a first position in which the attachment points are a first distance apart, to a second position in which the attachment points are a second distance apart, wherein the first distance is less than the second distance.

6. A stent as claimed in claim 5 wherein, between said attachment points, each closed cell element comprises proximal and distal members, spaced apart from each other in the direction of the longitudinal axis, said proximal and distal members being capable of bending to accommodate the expansion from the first position to the second position, wherein the proximal and distal members include the side members in each respective closed cell element.

7. A stent as claimed in claim 6 wherein the plurality of closed cell element comprises circumferentially spaced end hinge members joining the proximal and distal members of each closed cell element, wherein an end of the proximal and distal members of each closed cell element are joined together at a respective end hinge member.

8. A stent as claimed in claim 7 wherein each end hinge member is attached at one end of a respective circumferentially-extending linking member, the other end of the linking member having attached thereto the opposite end hinge member of the next adjacent closed cell element.

9. A stent as claimed in claim 6 wherein each of the proximal and distal members comprises a flexible member joining the attachment points.

10. A stent as claimed in claim 6 wherein each of the proximal and distal members comprises two or more relatively rigid side members joined by the side hinge.

11. A stent as claimed in claim 1 wherein said side members together form the shape of a rhombus.

12. A stent as claimed in claim 1 wherein each of said side members is of rectilinear shape.

13. A stent as claimed in claim 1 wherein all of the closed cell elements making up each tubular element are of the same shape.

14. A stent as claimed in claim 1 wherein some of the closed cell elements making up each tubular element are of a different shape to the remainder.

15. A stent as claimed in claim 1 wherein an exterior surface of the tubular body is equipped with wells which open onto the exterior surface, said wells being suitable to contain one or more therapeutic agents.

16. A stent as claimed in claim 15 in which the wells comprise holes or grooves opening into the exterior surface of the stent.

17. A stent as claimed in claim 16 wherein the holes or grooves are blind, such that the holes or grooves do not pass completely through the material of the stent.

18. A stent as claimed in claim 16 wherein the holes or grooves pass through to an interior of the stent.

19. A stent as claimed in claim 18 in which an inner end of the hole or groove is plugged by a material which prevents or considerably reduces the flow of a therapeutic agent therethrough.

20. A stent as claimed in claim 19 wherein said material contains a therapeutic agent.

21. A stent as claimed in claim 15 wherein the closed cell elements are formed with blocks on each of which are formed one or more of said wells.

22. A stent as claimed in claim 15 wherein at least some of said wells contain multiple therapeutic agents arranged in layers so as to release in sequence.

23. A stent as claim in claim 1, wherein the inter-engaging elements of adjacent tubular elements are configured to engage one another so as to interlock adjacent stents in the unexpanded configuration and are dis-engaged in the expanded configuration so as to inhibit shortening of the stent during expansion.