Occlusion perfusion catheter

• US 8,262,611 B2
• Filed: 09/09/2011
• Issued: 09/11/2012
• Est. Priority Date: 11/03/2008
• Status: Active Grant

• Current Assignee: Advanced Catheter Therapies, Inc.
• Original Assignee: Advanced Catheter Therapies, Inc.
• Inventors: Teeslink, C. Rex, Hoyns, Dirk V.
• Primary Examiner(s): BOUCHELLE, LAURA A
• Application Number:
  US13/228,922
• Publication Number:
  US 20120016294A1
• Time in Patent Office: 368 Days
• Field of Search: 604/96.01, 604/99.01, 604/99.02, 604/101.01, 604/101.03, 604/101.05, 604/101.06, 604/102.02, 604/919
• US Class Current: 604/101.03
• CPC Class Codes: A61B 1/043 for fluorescence imaging
• CPC Class Codes: A61B 17/12045 double occlusion, e.g. during anastomosis
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/12127 Double occlusion, e.g. for creating blood-free anastomosis site
• CPC Class Codes: A61B 5/02154 by optical transmission
• CPC Class Codes: A61B 5/02158 provided with two or more sensor elements
• CPC Class Codes: A61B 5/6853 with a balloon
• CPC Class Codes: A61M 1/90 Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
• CPC Class Codes: A61M 2025/0183 Rapid exchange or monorail catheters
• CPC Class Codes: A61M 2025/1013 with concentrically mounted balloons, e.g. being independently inflatable
• CPC Class Codes: A61M 2025/105 having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1079 having radio-opaque markers in the region of the balloon
• CPC Class Codes: A61M 2025/1093 having particular tip characteristics
• CPC Class Codes: A61M 2025/1097 with perfusion means for enabling blood circulation only while the balloon is in an inflated state, e.g. temporary by-pass within balloon
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3337 Controlling, regulating pressure or flow by means of a valve by-passing a pump
• CPC Class Codes: A61M 2205/3344 Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 25/1011 : Multiple balloon catheters
• CPC Class Codes: A61M 39/24 : Check- or non-return valves
• CPC Class Codes: A61M 5/007 : for contrast media

Abstract

Catheters for occluding, visualizing, irrigating, evacuating, and delivering agents to a treatment area are disclosed. The catheters comprise a catheter body comprising five lumens, first and second occlusion balloons coupled to the catheter body, an optional space-occupying balloon coupled to the catheter body and disposed between the first and second occlusion balloons, and an optional visualization means that enables visualization between the first and second occlusion balloons. Methods for using these catheters are also disclosed. A method comprises inflating the first and second occlusion balloons, inflating the space-occupying balloon, allowing fluid to exit via an evacuation lumen, optionally irrigating or aspirating to facilitate fluid exit via said lumen, and delivering an agent to a treatment area via the agent lumen.

Claims

1. A catheter comprising:

a) a catheter shaft having a longitudinal axis, a distal end having a shaft distal tip, and a proximal end;

b) a first balloon positioned on the shaft proximal to the shaft distal tip;

c) a second balloon positioned on the shaft proximal to the first balloon, wherein said second balloon is constructed of a non-compliant material;

d) a third balloon positioned on the shaft proximal to the second balloon;

e) an agent delivery segment positioned on the shaft between the first and third balloons and having one agent delivery segment orifice formed therein;

f) an aspiration segment positioned on the shaft between the first and third balloons and having one aspiration segment orifice formed therein; and

g) a guidewire lumen formed within the shaft and in communication with;

an opening formed in a proximal end of the catheter; and

an opening formed in a distal end of the catheter,

h) an agent delivery lumen in fluid communication with said agent delivery segment orifice; and

i) a first pressure-sensing means having proximal and distal ends and a length therebetween extending through said agent delivery lumen,

wherein said first pressure sensing means distal end is at the agent delivery segment orifice or within the agent delivery lumen, and wherein said agent delivery segment orifice and said aspiration segment orifice lie on opposite sides of said longitudinal axis.

2. The catheter of claim 1, wherein said first pressure-sensing means proximal end is in communication with a connector formed on the proximal end of the catheter shaft.

3. The catheter of claim 1, further comprising a first inflation lumen in communication with the first and third balloons.

4. The catheter of claim 3, wherein said first inflation lumen is further in communication with a first balloon inflation port formed on the proximal end of the catheter shaft.

5. The catheter of claim 1, further comprising a second inflation lumen in communication with the second balloon.

6. The catheter of claim 5, wherein said second inflation lumen is further in communication with a second balloon inflation port formed on the proximal end of the catheter shaft.

7. The catheter of claim 1, further comprising an aspiration lumen in communication with the aspiration segment orifice.

8. The catheter of claim 7, wherein said aspiration lumen is further in communication with an aspiration port formed on the proximal end of the catheter shaft.

9. The catheter of claim 8, further comprising a valve in communication with said aspiration port.

10. The catheter of claim 1, further comprising an agent delivery lumen in communication with the agent delivery segment orifice.

11. The catheter of claim 10, wherein said agent delivery lumen is further in communication with an agent delivery port formed on the proximal end of the catheter shaft.

12. The catheter of claim 10, further comprising a first pressure-sensing means having proximal and distal ends and a length therebetween extending through said agent delivery lumen, wherein said first pressure-sensing means proximal end is in communication with a connector formed on the proximal end of the catheter shaft and said first pressure-sensing means distal end is at the agent delivery segment orifice or within the agent delivery lumen.

13. The catheter of claim 12, further comprising a second pressure-sensing means having proximal and distal ends and a length therebetween extending through said agent delivery lumen, wherein said second pressure-sensing means proximal end is in communication with the connector formed on the proximal end of the catheter shaft and said second pressure-sensing means distal end is located within the agent delivery lumen.

14. A catheter comprising:

a) a catheter shaft having a longitudinal axis, a distal end having a shaft distal tip, and a proximal end;

b) a first balloon positioned on the shaft proximal to the shaft distal tip, a second balloon positioned on the shaft proximal to the first balloon, and a third balloon positioned on the shaft proximal to the second balloon, wherein said second balloon is constructed of a non-compliant material;

c) a first inflation lumen in communication with the first and third balloons, wherein said first inflation lumen is further in communication with a first balloon inflation port formed on the proximal end of the catheter shaft;

d) a second inflation lumen in communication with the second balloon, wherein said second inflation lumen is further in communication with a second balloon inflation port formed on the proximal end of the catheter shaft;

e) an agent delivery lumen, and an agent delivery segment positioned on the shaft between the second and third balloons and having one agent delivery segment orifice formed therein, wherein the agent delivery lumen is in communication with the agent delivery segment orifice and an agent delivery port formed on the proximal end of the catheter shaft;

f) an aspiration lumen, and an aspiration segment positioned on the shaft between the first and second balloons and having one aspiration segment orifice formed therein, wherein the aspiration lumen is in communication with the aspiration segment orifice and an aspiration port formed on the proximal end of the catheter shaft, said aspiration port optionally further comprising a valve in communication with the aspiration port;

g) a guidewire lumen formed within the shaft and in communication with an opening formed in a proximal end of the catheter and an opening formed in a distal end of the catheter;

h) a first pressure-sensing means having proximal and distal ends and a length therebetween extending through said agent delivery lumen, wherein said first pressure-sensing means proximal end is in communication with a connector formed on the proximal end of the catheter shaft and said first pressure-sensing means distal end is at the agent delivery segment orifice or within the agent delivery lumen; and

i) a second pressure-sensing means having proximal and distal ends and a length therebetween, wherein said second pressure-sensing means proximal end is in communication with the connector formed on the proximal end of the catheter shaft and said second pressure-sensing means distal end is located within the agent delivery lumen,

wherein said agent delivery segment orifice and said aspiration segment orifice lie on opposite sides of said longitudinal axis.

15. A catheter comprising:

a) a catheter shaft having a longitudinal axis, a distal end having a shaft distal tip, and a proximal end;

b) a first balloon positioned on the shaft proximal to the shaft distal tip;

c) a second balloon positioned on the shaft proximal to the first balloon;

d) an agent delivery segment positioned on the shaft between the first and second balloons and having one agent delivery segment orifice formed therein;

e) an aspiration segment positioned on the shaft between the first and second balloons and having one aspiration segment orifice formed therein;

f) a visualization means lumen in communication with a visualization means slot;

g) a visualization means extending through said visualization means lumen at least to said visualization means slot, wherein said visualization means may turn about the longitudinal axis via torque applied to said visualization means; and

h) a guidewire lumen formed within the shaft and in communication with;

an opening formed in a proximal end of the catheter; and

an opening formed in a distal end of the catheter,

wherein said agent delivery segment orifice and said aspiration segment orifice lie on opposite sides of said longitudinal axis.

16. The catheter of claim 15, further comprising a first inflation lumen in communication with the first and second balloons, wherein said first inflation lumen is further in communication with a first balloon inflation port formed on the proximal end of the catheter shaft.

17. The catheter of claim 15, further comprising a visualization means lumen in communication with a visualization means slot and containing at least a portion of said visualization means.

18. The catheter of claim 15, further comprising an aspiration lumen in communication with the aspiration segment orifice, wherein said aspiration lumen is further in communication with an aspiration port formed on the proximal end of the catheter shaft.

19. The catheter of claim 15, further comprising an agent delivery lumen in communication with the agent delivery segment orifice wherein said agent delivery lumen is further in communication with an agent delivery port formed on the proximal end of the catheter shaft.