Devices, systems, and methods for closure of cardiac openings

• US 8,262,694 B2
• Filed: 01/27/2005
• Issued: 09/11/2012
• Est. Priority Date: 01/30/2004
• Status: Expired due to Fees

• Current Assignee: WL Gore and Associates Incorporated (W.L. Gore and Associates)
• Original Assignee: WL Gore and Associates Incorporated (W.L. Gore and Associates)
• Inventors: Widomski, David R., Devellian, Carol A., Heneberry, Eileen M., Chanduszko, Andrzej J., Carr, Robert M.
• Primary Examiner(s): Dornbusch, Dianne
• Application Number:
  US11/045,027
• Publication Number:
  US 20050209636A1
• Time in Patent Office: 2,784 Days
• Field of Search: 623/23.72, 623/23.74, 606/213, 606/200, 606/199, 606/198, 606/191, 606/190, 606/108, 606/151, 128/831
• US Class Current: 606/213
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 17/12195 comprising a curable material
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
• CPC Class Codes: A61B 2017/00632 Occluding a cavity, i.e. closing a blind opening

Abstract

The invention generally relates to devices, systems, and methods for percutaneous closure of cardiac openings and obliteration of the cardiac cul-de-sacs. In one embodiment, a closure device includes a patch with an adhesive and/or a removable frame. The patch may be placed across a cardiac opening, such as a patent foramen ovale, or across a cardiac cul-de-sac, such as a left atrial appendage. In another embodiment, a closure device includes a balloon together with adhesives and/or substances for stimulating tissue growth coated on, or contained within, the balloon. The balloon may be inserted into a cardiac opening, such as the patent foramen ovale, or into a cardiac cul-de-sac, such as a left atrial appendage.

Claims

1. A system for percutaneous transluminal closure of a cardiac opening, comprising:

a catheter comprising a lumen, a proximal end, and a distal end;

a frame comprising a proximal end and a distal end, the frame enclosed within the lumen of the catheter and moveable beyond the distal end of the catheter, wherein the frame comprises a plurality of arms at the frame'"'"'s distal end, the plurality of arms being expandable from a closed position when maintained within the catheter to an open position when advanced beyond the distal end of the catheter, wherein each of the plurality of arms comprises a resilient coil at which the arm bends in the closed position; and

a patch comprising a plurality of hollow channels, said plurality of hollow channels are enclosed within the patch having a common first end and second ends away from the common first end, and is contiguous with the lumen of the catheter, wherein the plurality of arms of the frame are maintained within the plurality of hollow channels of the patch, and wherein the plurality of arms are retractable from the plurality of hollow channels to deploy the patch.

2. The system of claim 1, wherein the patch is coated with an adhesive.

3. The system of claim 2, wherein the adhesive is a light curable adhesive, and the system further comprises a light source that projects light through the hollow channels of the patch to cure the adhesive.

4. The system of claim 1, wherein the frame comprises a shape memory alloy.

5. The system of claim 4, wherein the shape memory alloy comprises nitinol.

6. The system of claim 1, wherein the patch comprises a bioresorbable material.

7. The system of claim 1, wherein the system is configured to inject an adhesive through the hollow channels of the patch, and the patch comprises at least one hole passing from the hollow channels to a surface of the patch through which the adhesive can pass to the surface of the patch.

8. The system of claim 7, wherein the adhesive is a light curable adhesive, and the system further comprises a light source that projects light through the hollow channels of the patch to cure the adhesive.