Transvalvular intraannular band for valve repair

• US 8,262,725 B2
• Filed: 04/16/2008
• Issued: 09/11/2012
• Est. Priority Date: 04/16/2008
• Status: Active Grant

• Current Assignee: Heart Rhythm Technologies, Inc.
• Original Assignee: Cardiovascular Technologies, LLC
• Inventors: Subramanian, Valavanur A.
• Primary Examiner(s): Willse, David H.
• Assistant Examiner(s): SHIPMON, TIFFANY P
• Application Number:
  US12/104,011
• Publication Number:
  US 20090264995A1
• Time in Patent Office: 1,609 Days
• Field of Search: 623/2.1, 623 236- 239, 623/900
• US Class Current: 623/2.36
• CPC Class Codes: A61F 2/2454 Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses

Abstract

Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band having an elongate and arcuate body. The elongate and arcuate body has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is displaced from the plane containing the first end and the second end. The transvalvular band is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets and the central portion is displaced towards the left ventricle relative to the first anchoring portion and the second anchoring portion. The ventricular direction displacement moves coaption to an earlier point in the cardiac cycle.

Claims

1. A method of treating a mitral valve, the method comprising:

implanting in the mitral annulus an intraannular band comprising an elongate body having a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion, wherein the central portion has a convex arcuate shape, the central portion displaced out of an intraannular plane of the mitral valve, said plane containing the first end and the second end;

attaching the first anchoring portion to a first portion of the mitral annulus; and

attaching the second anchoring portion to a second portion of the mitral annulus such that the intraannular band extends transversely across coaptive edges formed by the closure of the mitral valve leaflets during systole and the central portion is convex in the direction of the left ventricle relative to the first anchoring portion and the second anchoring portion to elevate the position of the coaptive edges in the direction of the ventricle during valve closure and thereby cause early coaption relative to the cardiac cycle,

wherein the coaptive edges of the leaflets are unsupported by the band during diastole, and

wherein attaching the first and second anchoring portions does not affect the size and shape of the mitral annulus.

2. A method of treating a mitral valve as in claim 1, wherein the first anchoring portion comprises an arcuate shape.

3. A method of treating a mitral valve as in claim 2, wherein the first anchoring portion extends around a portion of the circumference of the mitral annulus.

4. A method of treating a mitral valve as in claim 3, wherein the second anchoring portion extends around a portion of the circumference of the mitral annulus.

5. A method of treating a mitral valve as in claim 3, wherein the first anchoring portion has an arc length of greater than about 5 mm.

6. A method of treating a mitral valve as in claim 5, wherein the first anchoring portion has an arc length of greater than about 1 cm.

7. A method of treating a mitral valve as in claim 5, wherein the first anchoring portion has an arc length of greater than about 2 cm.

8. A method of treating a mitral valve as in claim 1, wherein the second anchoring portion comprises an arcuate shape.

9. A method of treating a mitral valve as in claim 1, wherein the central portion comprises a narrowed portion configured to reduce resistance to blood flow.

10. A method of treating a mitral valve as in claim 1, wherein the method treats mitral valve prolapse.

11. A method of treating a mitral valve as in claim 1, wherein the method treats mitral valve regurgitation.

12. A method of treating a mitral valve as in claim 1, wherein the central portion is narrower than that of the first anchoring portion and the second anchoring portion.

13. A method of treating a mitral valve as in claim 1, wherein the first anchoring portion comprises a plurality of apertures.

14. A method of treating a mitral valve as in claim 1, wherein attaching the first anchoring portion to a first portion of the mitral annulus comprises suturing the first anchoring portion to the first portion of the mitral annulus.

15. A method of treating a mitral valve as in claim 1, wherein attaching the second anchoring portion to a second portion of the mitral annulus comprises suturing the second anchoring portion to the second portion of the mitral annulus.

16. A method of moving mitral valve leaflet coaption to an earlier point in the cardiac cycle, comprising the steps of:

providing an intraannular, transvalvular band dimensioned for attachment within a plane of the mitral valve annulus, wherein the band comprises an elongate body having a first end, a second end, and a central portion having a convex arcuate shape, wherein the band does not comprise an annuloplasty ring;

attaching the band within the plane of the annulus such that the arcuate shaped portion of the band extends transversely across coaptive edges formed by the mitral valve leaflets and is convex in the direction of the ventricular side of the plane to support the leaflets and elevate the position of the coaptive edges in the direction of the ventricle during valve closure,

wherein the coaptive edges of the leaflets are unsupported by the band during diastole.

17. A method of moving mitral valve leaflet coaption as in claim 16, wherein the elevate the position step comprises elevating the position of the coaptive edges by at least about 4 mm.

18. A method of moving mitral valve leaflet coaption as in claim 16, wherein the elevate the position step comprises elevating the position of the coaptive edges by an amount within the range of from about 6 mm to about 12 mm.

19. A method of treating a mitral valve as in claim 16, wherein the position of the coaptive edges is elevated by at least about 4 mm.

20. A method of treating a mitral valve as in claim 16, wherein the position of the coaptive edges is elevated by an amount within the range of about 6 mm to about 12 mm.

21. A method of moving mitral valve leaflet coaption to an earlier point in the cardiac cycle, comprising the steps of:

providing an intraannular, transvalvular band dimensioned for attachment within a plane of the mitral valve annulus, wherein the band comprises an elongate body having a first end, a second end, and an arcuate central portion;

attaching the band within the plane of the annulus such that the arcuate shaped portion of the band extends transversely across coaptive edges formed by the mitral valve leaflets and extends into the ventricular side of the plane to support the leaflets and elevate the position of the coaptive edges in the direction of the ventricle during valve closure,

wherein the coaptive edges of the leaflets are unsupported by the band during diastole, and

wherein attachment of the band does not affect the size and shape of the mitral valve annulus.