Modular sensor cassette

• US 8,262,992 B2
• Filed: 11/12/2008
• Issued: 09/11/2012
• Est. Priority Date: 11/13/2007
• Status: Active Grant

• Current Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Kontschieder, Heinz, Leiner, Marco Jean Pierre, Huber, Wolfgang, Krysl, Franz-Josef, Ritter, Christoph, Offenbacher, Helmut, Schaffar, Bernhard, Schinnerl, Marie-Luise, Harer, Johann
• Primary Examiner(s): Ramdhanie, Bobby
• Application Number:
  US12/269,280
• Publication Number:
  US 20090156966A1
• Time in Patent Office: 1,399 Days
• Field of Search: 422/58, 422/63, 422/554
• US Class Current: 422/63
• CPC Class Codes: B01L 2200/027 for microfluidic devices
• CPC Class Codes: B01L 2200/028 Modular arrangements
• CPC Class Codes: B01L 2300/021 Identification, e.g. bar codes
• CPC Class Codes: B01L 2300/022 Transponder chips
• CPC Class Codes: B01L 2300/0627 Sensor or part of a sensor is integrated
• CPC Class Codes: B01L 2300/0645 Electrodes
• CPC Class Codes: B01L 2300/1805 Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
• CPC Class Codes: B01L 2300/1883 using thermal insulation
• CPC Class Codes: B01L 2400/0481 squeezing of channels or chambers
• CPC Class Codes: B01L 2400/0655 pinch valves
• CPC Class Codes: B01L 3/502715 characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
• CPC Class Codes: G01N 33/48771 Coding of information, e.g. calibration data, lot number

Abstract

The invention concerns a sensor cassette that can be inserted into an analyzer comprising a continuous measuring channel for receiving fluidic media and sensory elements for determining chemical and/or physical parameters of the fluidic media. According to the invention the sensor cassette consists of at least two permanently connected but separately manufactured modules which each have a housing and a measuring channel section wherein the measuring channel sections of adjacent modules are connected to the continuous measuring channel by a fluidic coupling and wherein at least one of the connected modules is designed as a sensor module and has a sensor array comprising at least two sensory elements. Furthermore, a memory element is allocated to the sensor cassette on which specific information for the sensor cassette in particular with regard to its construction from the respective modules is stored.

Claims

1. A sensor cassette that can be inserted into a holder of an analyzer, the sensor cassette comprising:

a continuous measuring channel for receiving fluidic media and sensory elements for determining at least one of;

chemical parameters of the fluidic media physical parameters of the fluidic media;

at least two permanently coupled but separately manufactured modules, the modules each having a housing and a measuring channel section, wherein;

the measuring channel sections of adjacent modules are permanently coupled to the continuous measuring channel by a fluidic coupling;

at least one of the modules is designed as a sensor module and has a sensor array comprising at least two sensory elements;

the modules collectively define the sensor cassette, the sensor cassette having dimensions that correspond to dimensions of the holder of the analyzer; and

fluid connections of the sensor cassette align with corresponding fluid connections of the holder of the analyzer when the sensor cassette is inserted into the holder of the analyzer; and

a memory element on the sensor cassette with information stored thereon, wherein, when the sensor cassette is inserted into the holder of the analyzer, the information is read out by the analyzer and instructs a processor of the analyzer to configure the analyzer for interaction with the sensor cassette.

2. The sensor cassette according to claim 1, wherein at least one of the modules is a dummy module which, apart from the absence of sensory elements, is constructed in essentially the same manner as the respective sensor module.

3. The sensor cassette according to claim 1, wherein at least one sensor module includes a sensor array comprising at least two sensory elements and a free region which is free of sensory elements.

4. The sensor cassette according to claim 1, wherein at least two of the modules of the sensor cassette are coupled together by a permanent mechanical snap connection.

5. The sensor cassette according to claim 1, wherein at least two of the modules of the sensor cassette are permanently coupled together by at least one of:

locking elements, a welded joint, and a bonded joint.

6. The sensor cassette according to claim 1, wherein the modules have one or more thermal contact zones.

7. The sensor cassette according to claim 6, wherein the thermal contact zones are configured such that the modules can be set to different operating temperatures.

8. The sensor cassette according to claim 6, wherein the thermal contact zones of adjacent modules of the sensor cassette are thermally decoupled.

9. The sensor cassette according to claim 1, wherein a module at the edge of the sensor cassette has a grip part.

10. The sensor cassette according to claim 1, wherein the information stored on the memory element configures the analyzer by describing the type of modules used and their arrangement or position within the sensor cassette.

11. The sensor cassette according to claim 1, wherein the information stored on the memory element configures the analyzer by describing the manner in which the individual sensory elements or free regions are arranged within the respective modules and/or instructions on the use of the modules for the analyzer.

12. The sensor cassette according to claim 11, wherein the information stored on the memory element further configures the analyzer by describing the arrangement and/or use of electrical contact points or other signal transferring regions, fluidic connections, thermal contact zones and/or fluidic control elements within the individual modules.

13. The sensor cassette according to claim 1, wherein the information stored on the memory element configures the analyzer by describing the type of individual sensory elements and/or their use and actuation.

14. The sensor cassette according to claim 13, wherein the information stored on the memory element further configures the analyzer by describing includes production information, response curve data and/or calibration information or shelf life information of the respective sensory element.

15. The sensor cassette according to claim 1, wherein the memory element is an electronic memory element.

16. The sensor cassette according to claim 1, wherein the memory element is selected from the group consisting of memory chips, memory cards, RFID transponders, magnetic strips, optical codes, and combinations thereof.

17. The sensor cassette according to claim 16, wherein the optical code is a one-dimensional or two-dimensional bar code.

18. The sensor cassette according to claim 1, wherein the memory element is permanently connected to the sensor cassette.

19. The sensor cassette according to claim 18, wherein the memory element is permanently coupled to the sensor cassette by a select one of:

mounting the memory element on the sensor cassette, or incorporating a memory element into the sensor cassette during its assembly.

20. The sensor cassette according to claim 1, wherein the sensor elements and electrical contact points of at least one module are arranged on a carrier part.

21. The sensor cassette according to claim 20, wherein the modules have one or more thermal contact zones defined by the carrier part and the thermal contact zones each include a temperature control device operated by the analyzer.

22. The sensor cassette according to claim 1, wherein at least one of the modules comprises a sensor array having at least two sensory elements and corresponding electrical contact points, wherein the electrical contact points align with corresponding electrical contact points in the analyzer when the sensor cassette is inserted into the holder of the analyzer.

23. A sensor cassette that can be inserted into a holder of an analyzer, the sensor cassette comprising:

a continuous measuring channel for receiving fluidic media and sensory elements for determining at least one of;

chemical parameters of the fluidic media and physical parameters of the fluidic media; and

at least two inseparably connected but separately manufactured modules, the modules each having a housing and a measuring channel section, wherein;

the measuring channel sections of adjacent modules are permanently coupled to the continuous measuring channel by a fluidic coupling;

at least one of the modules is designed as a sensor module and has a sensor array comprising at least two sensory elements;

the modules collectively define the sensor cassette, the sensor cassette having dimensions that correspond to dimensions of the holder of the analyzer; and

fluid connections of the sensor cassette align with corresponding fluid connections of the holder of the analyzer when the sensor cassette is inserted into the holder of the analyzer; and

a memory element on the sensor cassette with information stored thereon, wherein, when the sensor cassette is inserted into the holder of the analyzer, the information is read out by the analyzer and instructs a processor of the analyzer to configure the analyzer for interaction with the sensor cassette.