Process for putting into operation and for operating a measuring device

• US 8,262,999 B2
• Filed: 02/23/2009
• Issued: 09/11/2012
• Est. Priority Date: 04/04/2008
• Status: Active Grant

• Current Assignee: Draeger Safety Incorporated (Dragerwerk AG)
• Original Assignee: Draeger Safety Incorporated (Dragerwerk AG)
• Inventors: Wuske, Thomas, Polzius, Rainer, Lange, Björn, Kaneblei, Ingo
• Primary Examiner(s): Warden, Jill
• Assistant Examiner(s): Handy, Dwayne K
• Application Number:
  US12/390,715
• Publication Number:
  US 20090249894A1
• Time in Patent Office: 1,296 Days
• Field of Search: 422/63, 422/65, 422/67, 422/68.1, 422/82.05, 422/82.09, 422/82.12, 422/400, 422/402, 422/403, 422/408, 422/430, 422/501, 422/509, 422/529, 422/530, 436/43, 436/44, 436/46, 436/47, 436/164, 436/165, 436/169, 436/518, 436/809, 436/174, 436/176, 435/4, 435/7.1, 435/7.4, D24/216, D24/223, D24/224, D24/227, 738/63, 738/639.1, 738/649.1, 702/22, 702/127, 356/244
• US Class Current: 422/82.05
• CPC Class Codes: G01N 33/54366 Apparatus specially adapted for solid-phase testing
• CPC Class Codes: Y10T 436/25 including sample preparation
• CPC Class Codes: Y10T 436/2525 Stabilizing or preserving

Abstract

Tempering of sample (58) in test strip (37) is carried out by temperature regulating unit (40) and heating/cooling unit (92). The sample is fed to the test strip by a developer fluid (57) and a metering unit (55). The result of the detection reaction becomes visible by a change in color (36), which is detected optically and analyzed. The data of a control chart (52) with the measured values of first and second temperature sensors (41, 42) are used to set the control parameters for tempering. Code (86) on the test sample holder (35) is read in a sequence of steps. Parameters for phases of the measurement are determined from measured values of first and second temperature sensors, values of the control chart and the code of the test sample holder. These parameters are used by the temperature regulating unit during the measurement.

Claims

1. A measuring device comprising:

an electronic unit including a central control unit, a sequential control and a control chart;

an optical analysis unit with an optical reading element;

a metering unit;

a fluid tank containing a developer fluid;

a holder for said fluid tank;

a temperature regulating unit;

a test sample holder;

a heating/cooling element with a tempering block for generating a tempered zone of the test sample holder;

a first temperature sensor;

a second temperature sensor, said first temperature sensor and said second temperature sensor being provided for detecting an ambient temperature and a temperature of the tempering block respectively, said central control unit selectively setting a temperature of said tempering block based on the ambient temperature and information from said control chart, said control unit controlling a set temperature of said tempering block using said second temperature sensor; and

a contact means for controlling the measuring operation.

2. A measuring device in accordance with claim 1, wherein the contact means is a button that can be actuated by a user.

3. A measuring device in accordance with claim 1, further comprising a device housing with a device door which separates the measuring device from the environment.

4. A measuring device in accordance with claim 1, wherein the contact means is provided for monitoring the status of the device.

5. A measuring device in accordance with claim 4, wherein the contact means is a switching contact actuated by a contact maker located on the device door.

6. A measuring device in accordance with claim 4, wherein the contact means is a switching contact actuated by a contact maker located at the test sample holder.

7. A measuring device in accordance with claim 4, wherein the contact means is a switching contact actuated by a contact maker located at the fluid tank.

8. A measuring device in accordance with claim 4, wherein the test sample holder comprises a contact maker of said contact means.

9. A measuring device in accordance with claim 4, wherein the fluid tank comprises a contact maker of said contact means.

10. A measuring device in accordance with claim 4, wherein said contact means comprises contact elements with one of said contact elements comprising a photoelectric cell.

11. A measuring device in accordance with claim 4, wherein the contact means comprises contact elements including an electromechanical contact actuated by an external magnetic field effect and a contact maker made of a magnetic material and generating a magnetic field to bring about an actuation of the contact element when approaching said contact element.

12. A measuring device in accordance with claim 1, wherein said test sample holder is provided with a code.

13. A measuring device in accordance with claim 1, wherein said optical reading element comprises means for reading a code at said test sample holder and wherein said optical analysis unit is designed to analyze the code.

14. A measuring device in accordance with claim 1, wherein the heating/cooling element comprises a separate heating element and as a separate cooling element, which are arranged together at said tempering block and are actuated by said temperature regulating unit.

15. A measuring device in accordance with claim 1, further comprising an additional heating element.

16. A measuring device in accordance with claim 1, further comprising an electric energy storage unit connected to said temperature regulating unit.

17. A measuring device in accordance with claim 1, wherein:

values of the ambient temperature are entered in a specification column in said control chart with a first value block provided for a first phase, comprising a first set of temperature values and a first set of time period values, and with a second value block provided for a second phase, comprising a second set of temperature values and a second set of time period values;

a code of the test sample holder and the ambient temperature and the temperature of the tempering block and the first and at least one second value block are used as controlled variables for said temperature regulating unit for regulating the temperature of said tempering block and for said metering unit for metering said developer fluid onto a test strip.

18. A measuring device in accordance with claim 17, further comprising a data interface wherein a refreshing of the data of the control chart by means of data transmission via said data interface is provided.

19. A measuring device in accordance with claim 1, wherein the optical reading element is for reading a color change on a test strip in said test sample holder and wherein said optical analysis unit is designed to analyze the color change.

20. A measuring device for measuring a test sample in a test sample holder, the device comprising:

a housing;

a tempering zone arranged in said housing, said tempering zone being receivable of the test sample holder, said tempering zone being capable of adjusting a temperature of the test sample holder when the test sample holder is in said tempering zone;

a fluid tank arranged in said housing to flow a developer fluid to the test sample holder, when the test sample holder is in said tempering zone;

an optical analysis unit arranged in said housing, said optical analysis unit including an optical reading element arranged to read the test sample holder when the test sample holder is in said tempering zone, said optical analysis unit measuring details of the test sample in the test sample holder;

a first temperature sensor connected to said housing and measuring an ambient temperature of air inside said housing;

a second temperature sensor connected to said housing and measuring a temperature of said tempering zone which adjusts the temperature of the test sample holder;

a control unit connected to said tempering zone, connected to said first temperature sensor and connected to said second temperature sensor, said control unit selectively setting a temperature of said tempering zone based on the ambient temperature.

21. A measuring device in accordance with claim 20, wherein:

said tempering zone selectively heats and cools the test sample holder according to commands from said control unit.

22. A measuring device in accordance with claim 20, wherein:

said control unit selectively sets the temperature of said tempering zone in a first phase and a second phase, said first phase having a first temperature and a first time interval, said second phase having a second temperature and a second time interval.

23. A measuring device in accordance with claim 22, wherein:

values of said first temperature, said second temperature, said first time interval and said second time interval are selectively set by said control unit dependent on the ambient temperature measured by said first temperature sensor.

24. A measuring device in accordance with claim 23, further comprising:

a temperature control chart connected to said control unit and providing said values of said first temperature, said second temperature, said first time interval and said second time interval dependent on the ambient temperature measured by said first temperature sensor, said first temperature and said second temperature being different for one of the ambient temperatures.

25. A measuring device in accordance with claim 20, further comprising:

a code reader connected to said housing and readable of a code on the test sample holder;

said control unit receiving the code from said code reader, said control unit selectively setting the temperature of said tempering zone based on the ambient temperature and the code read from the test sample holder by said code reader.

26. A measuring device in accordance with claim 22, further comprising:

a code reader connected to said housing and reading a code on the test sample holder;

a temperature control chart connected to said control unit and providing values for said first temperature, said second temperature, said first time interval and said second time interval dependent on the ambient temperature measured by said first temperature sensor and the code read from the test sample holder;

said control unit receiving the code from said code reader, said control unit selectively setting the temperature of said tempering zone based on said temperature control chart, the ambient temperature and the code read from the test sample holder.

27. A measuring device in accordance with claim 25, wherein:

said control unit controls a set temperature of said tempering block using said second temperature sensor;

said optical analysis unit is also said code reader.

28. A measuring device in accordance with claim 20, wherein:

said control unit selectively sets a temperature of said tempering zone in a first phase and a second phase, said first phase having a first temperature and a first time interval, said second phase having a second temperature and a second time interval;

said control unit is also connected to said fluid tank and controls said fluid tank to selectively flow the developer fluid to the test sample holder, said control unit flowing the developer fluid to the test sample holder between said first phase and said second phase.

29. A process for operating a measuring device comprising an electronic unit including a central control unit, a sequential control and a control chart, an optical analysis unit with an optical reading element, a metering unit, a fluid tank containing a developer fluid, a holder for the fluid tank, a temperature regulating unit, a test sample holder, a heating/cooling element with a tempering block for generating a tempered zone of the test sample holder, temperature sensors for detecting the ambient temperature and the temperature of the tempering block and a contact means for controlling the measuring operation, the process comprising the steps of:

transferring a section of a process control from the central control unit to the sequential control and to the temperature regulating unit;

polling first and second of the temperature sensors and preparing the temperature regulating unit;

inserting the test sample holder into the measuring device;

closing the measuring device by closing a measuring device housing door;

polling one or more contact elements;

polling a code on the test sample holder;

using the control chart, the code and the measured values of the temperature sensors to determine control parameters for tempering;

tempering of the tempering block and setting the temperature of the tempering block by the temperature regulating unit based on the ambient temperature;

metering the developer fluid onto a sample by means of the metering unit;

additional tempering of the tempering block and setting of the temperature of the tempering block by the temperature regulating unit is performed after said metering;

ending tempering; and

transferring the process control to the central control unit.

30. A process in accordance with claim 29, further comprising feeding of a defined quantity of the developer fluid from a storage tank in an interior space of the measuring device to the metering unit.

31. A process in accordance with claim 29, wherein pretempering of the tempering block is carried out during or soon before or soon after said step of polling the first and second temperature sensors.

32. A process in accordance with claim 29, further comprising:

maintaining a set temperature of said tempering block using the detected temperature of the tempering block and according to a proportional-integral control characteristic.