Advanced ablation planning
First Claim
1. A method for planning an ablation procedure to eliminate a tissue mass in a patient, including:
- identifying a tissue mass in the patient;
generating an image representation of an initial planned target volume (PTV) encompassing the tissue mass;
inscribing the initial PTV in a template ellipsoidal enclosing ablation volume;
scaling minor axes of the template ellipsoidal enclosing ablation volume and the initial PTV upward until they are equal in magnitude to a major axis of the template ellipsoidal enclosing ablation volume, to generate an enclosing sphere that encompasses the scaled PTV;
identifying in a lookup table a pre-computed ablation solution having a minimum number of spherical ablation regions that cover the enclosing sphere; and
outputting to a user a graphical representation of the identified precomputed ablation solution overlaid on the sphere.
1 Assignment
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Accused Products
Abstract
In planning an ablation procedure, a planned target volume (PTV) is imported, which is typically selected by a doctor but may be computer-identified. An ablation solution comprising a plurality of ablation volumes is generated or selected using a lookup table. Ablations sharing a common axis along a line of insertion are grouped into blocks. Alternatively, the PTV is enveloped in a sphere, and a pre-computed ablation solution (e.g., a 6- or 14-sphere solution) is identified to cover the PTV sphere. Optionally, a mathematical algorithm is executed to increase an axis through the ablation spheres to generate ellipsoidal ablation volumes that envelop the PTV.
111 Citations
18 Claims
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1. A method for planning an ablation procedure to eliminate a tissue mass in a patient, including:
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identifying a tissue mass in the patient; generating an image representation of an initial planned target volume (PTV) encompassing the tissue mass; inscribing the initial PTV in a template ellipsoidal enclosing ablation volume; scaling minor axes of the template ellipsoidal enclosing ablation volume and the initial PTV upward until they are equal in magnitude to a major axis of the template ellipsoidal enclosing ablation volume, to generate an enclosing sphere that encompasses the scaled PTV; identifying in a lookup table a pre-computed ablation solution having a minimum number of spherical ablation regions that cover the enclosing sphere; and outputting to a user a graphical representation of the identified precomputed ablation solution overlaid on the sphere. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method for planning an ablation procedure to eliminate a tissue mass in a patient, including:
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identifying a tissue mass in the patient; generating an image representation of an initial planned target volume (PTV) encompassing the tissue mass; selecting a bounding polyhedron as a function of a tumor-to-ablation (TA) factor that describes a relationship between radius of a known ellipsoidal ablation volume radius and radius of the PTV; positioning the bounding polyhedron around the PTV; positioning an ellipsoidal ablation volume in the bounding polyhedron such that a center of the ellipsoidal ablation volume coincides with a center of the bounding polyhedron; increasing the TA factor by which axes of the ellipsoidal ablation volume are multiplied until the axes are equal to or greater than corresponding dimensions of the bounding polyhedron; identifying in a lookup table a pre-computed ablation solution having a minimum number of spherical ablation regions that cover the enclosing sphere; and outputting to a user a graphical representation of the identified precomputed ablation solution overlaid on the scaled PTV. - View Dependent Claims (8, 9, 10, 11)
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12. A system for planning an ablation procedure for ablation of a tissue mass in a patient, including:
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a graphical user interface that presents a representation of the tissue mass to a user; and an optimization component that generates a planned target volume (PTV), which includes the tissue mass, receives image data related to the tissue mass, generates an enclosing ellipsoid ablation volume that encompasses the PTV, identifies a polyhedron shape that encompasses the enclosing ellipsoid, identifies a plurality of spheroid ablation regions to cover the enclosing ellipsoid having respective centroids positioned on centers respective sides of the polyhedron shape, executes a mathematical algorithm to lengthen an axis of the spherical ablation regions to form ellipsoid ablation regions therefrom, and outputs graphical information to the user displaying the ellipsoid ablation regions overlaid on the PTV. - View Dependent Claims (13, 14, 15, 16, 17, 18)
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Specification