Patient alignment system with external measurement and object coordination for radiation therapy system

• US 8,269,195 B2
• Filed: 11/04/2008
• Issued: 09/18/2012
• Est. Priority Date: 08/12/2003
• Status: Expired due to Fees

• Current Assignee: LOMA Linda University Medical Center (Mission Healthcare Services LLC)
• Original Assignee: LOMA Linda University Medical Center (Mission Healthcare Services LLC)
• Inventors: Rigney, Nickolas S., Anderson, Daniel C., Lesyna, David A., Miller, Daniel W., Moyers, Michael F., Cheng, Chieh C., Baumann, Michael A.
• Primary Examiner(s): Berman, Jack
• Assistant Examiner(s): Sahu, Meenakshi
• Application Number:
  US12/264,854
• Publication Number:
  US 20090067577A1
• Time in Patent Office: 1,414 Days
• Field of Search: 250/492.1, 250/491.1, 250/492.3, 356/375, 356/373, 378/20, 378/65, 378/68
• US Class Current: 250/492.3
• CPC Class Codes: A61B 2090/3937 Visible markers
• CPC Class Codes: A61B 6/0442 made of non-metallic materials
• CPC Class Codes: A61B 6/4092 for producing synchrotron radiation
• CPC Class Codes: A61B 6/547 involving tracking of position of the device or parts of the device
• CPC Class Codes: A61N 2005/105 using a laser alignment system
• CPC Class Codes: A61N 2005/1059 using cameras imaging the patient
• CPC Class Codes: A61N 2005/1061 using an x-ray imaging system having a separate imaging source
• CPC Class Codes: A61N 2005/1062 using virtual X-ray images, e.g. digitally reconstructed radiographs [DRR]
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 2005/1097 Means for immobilizing the patient
• CPC Class Codes: A61N 5/1037 taking into account the movement of the target, e.g. 4D-image based planning
• CPC Class Codes: A61N 5/1049 for verifying the position of the patient with respect to the radiation beam
• CPC Class Codes: A61N 5/1067 in real time, i.e. during treatment
• CPC Class Codes: A61N 5/1069 Target adjustment, e.g. moving the patient support
• CPC Class Codes: A61N 5/107 in real time, i.e. during treatment
• CPC Class Codes: A61N 5/1078 Fixed beam systems
• CPC Class Codes: B25J 9/1666 Avoiding collision or forbidden zones
• CPC Class Codes: G05B 15/02 electric
• CPC Class Codes: G05B 2219/45117 Medical, radio surgery manipulator

Abstract

A patient alignment system for a radiation therapy system. The alignment system includes multiple external measurement devices which obtain position measurements of components of the radiation therapy system which are movable and/or are subject to flex or other positional variations. The alignment system employs the external measurements to provide corrective positioning feedback to more precisely register the patient and align them with a radiation beam. The alignment system can be provided as an integral part of a radiation therapy system or can be added as an upgrade to existing radiation therapy systems.

Claims

1. A control system for a radiation therapy system comprising a moveable patient positioner and a moveable radiation nozzle, wherein the control system generates control signals to induce movement of at least one of the patient positioner and the radiation nozzle and wherein the control system further receives position signals from a plurality of external measurement devices, each of the plurality of external measurement devices being arranged to independently provide position information indicative of a current spatial position of one or more of the patient positioner, of the radiation nozzle, and of fixed reference objects and wherein the control system calibrates the position signals from each of the plurality of external measurement devices with each other and to the fixed reference objects and wherein the control system further generates the control signals so as to induce at least one of the patient positioner and the radiation nozzle to move to achieve a desired translational and rotational alignment of the patient positioner with respect to the radiation nozzle.

2. The control system of claim 1, wherein the control system comprises:

a motion control module that generates the control signals;

a 6-D module that determines 6-dimensional spatial positions of at least the patient positioner and the radiation nozzle with respect to the fixed reference objects; and

a command and control module in communication with the motion control and 6-D modules.

3. The control system of claim 2, further comprising a patient registration module in communication with the command and control module wherein the patient registration module determines a registration transformation between a computer tomography orientation and a treatment session set-up pose.

4. The control system of claim 1, wherein the system further receives position signals from the external measurement devices indicating a current position of one or more movable imagers that can be arranged to obtain image data of at least a portion of the patient positioner and wherein the system determines a position of the one or more imagers with respect to the fixed reference objects.

5. The control system of claim 4, wherein the control system receives position signals from the one or more moveable imagers indicative of a spatial position of a target iso-center of a patient affixed to the patient positioner and wherein the control system generates the control signals so as to induce the patient positioner to move so as to align the target iso-center at a desired translational and rotational position.

6. The control system of claim 1, wherein the control system receives position signals from two or more external measurement devices arranged to provide independent position information for each of the patient positioner and the radiation nozzle respectively from multiple perspectives.

7. The control system of claim 1, wherein the position signals from the plurality of external measurement devices comprise direction vectors and wherein the control system calculates intersections of pluralities of the direction vectors.

8. The control system of claim 7, wherein the control system further determines a translational location and rotational orientation of each of the patient positioner and of the radiation nozzle based at least in part on the calculated intersections of the direction vectors.

9. The control system of claim 1, wherein the system further receives independent secondary local position signals indicative of the current position of the patient positioner and of the radiation nozzle and wherein the system generates the control signals as a function of both the position signals from the external measurement devices and from the secondary position signals.

10. A method of determining positions of movable components of a radiation therapy system, the method comprising:

externally measuring positions of a plurality of fixed monuments;

defining a fixed frame of reference based on the plurality of fixed monuments;

externally measuring position of one or more monuments of at least one movable component of a radiation therapy system;

calibrating the measured position of the one or more monuments of the at least one movable component with respect to the defined fixed frame of reference; and

calculating a translational location and rotational orientation of the at least one movable component with respect to the fixed frame of reference.

11. The method of claim 10, comprising externally measuring the position of the one or more monuments of the at least one movable component via two or more external measurement devices so as to perform a binocular measurement.

12. The method of claim 10, wherein the externally measuring the position of the one or monuments of the at least one movable component comprises performing direction measurements so as to determine a plurality of direction vectors.

13. The method of claim 12, comprising calculating intersections of the plurality of direction vectors and wherein calculating the translational location and rotational orientation is based at least in part on the calculated intersections.

14. The method of claim 10, comprising:

externally measuring positions of one or more monuments of a plurality of movable component of the radiation therapy system; and

calibrating the measured position of the one or more monuments of the plurality of movable components with respect to each other and with respect to the fixed frame of reference.

15. The method of claim 10, further comprising generating movement commands to induce the at least one movable component to move to a desired translational location and rotational orientation.

16. The method of claim 15, further comprising:

generating first movement commands to induce the at least one movable component to move to a first desired translational location and rotational orientation with respect to the fixed frame of reference;

externally remeasuring position of the one or more monuments of the at least one movable component after movement according to the first movement commands occurs; and

recalculating the translational location and rotational orientation of the at least one movable component with respect to the fixed frame of reference.

17. The method of claim 16, further comprising:

generating second movement commands to induce at least second movable component to move to a second desired translational location and rotational orientation with respect to the fixed frame of reference;

externally remeasuring position of the one or more monuments of the at least second movable component after movement according to the second movement commands occurs; and

calculating the translational location and rotational orientation of the at least second movable component with respect to the fixed frame of reference.

18. The method of claim 10, further comprising independently performing at least second local position measurements of the at least one movable component.