Pumping cassette

• US 8,273,049 B2
• Filed: 10/12/2007
• Issued: 09/25/2012
• Est. Priority Date: 02/27/2007
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Demers, Jason A., Wilt, Michael J., Grant, Kevin L., Dale, James D., Tracey, Brian
• Primary Examiner(s): Zalukaeva, Tatyana
• Assistant Examiner(s): Wiest, Philip R
• Application Number:
  US11/871,680
• Publication Number:
  US 20080208103A1
• Time in Patent Office: 1,810 Days
• Field of Search: 604/4.01, 604/5.01, 604/6.01, 604/6.09, 604/6.1, 604/6.11, 604/6.16, 604/403, 422/44, 210645-647, 210250-252, 210/650, 210/97, 210/98
• US Class Current: 604/6.11
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/15625 the reservoirs acting as balance chambers
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/1639 linked by membranes
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/1664 with temperature control
• CPC Class Codes: A61M 1/1666 by dissolving solids
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3324 PH measuring means
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/268 the displacement member being flexible, e.g. membranes, diaphragms or bladders
• CPC Class Codes: A61M 60/37 Haemodialysis, haemofiltration or diafiltration
• CPC Class Codes: A61M 60/427 : the force acting on the blood contacting member being hydraulic or pneumatic
• CPC Class Codes: A61M 60/43 : using vacuum at the blood pump, e.g. to accelerate filling
• CPC Class Codes: A61M 60/837 : Aspects of flexible displacement members, e.g. shapes or materials
• CPC Class Codes: A61M 60/847 : arranged in a cassette
• CPC Class Codes: A61M 60/849 : Disposable parts
• CPC Class Codes: A61M 60/851 : Valves
• CPC Class Codes: A61M 60/892 : Active valves, i.e. actuated by an external force
• CPC Class Codes: A61M 60/894 : Passive valves, i.e. valves actuated by the blood
• CPC Class Codes: F04B 13/02 : of two or more fluids at the same time
• CPC Class Codes: F04B 23/06 : the pumps being all of reciprocating positive-displacement type
• CPC Class Codes: F04B 41/06 : Combinations of two or more pumps
• CPC Class Codes: F04B 43/00 : Machines, pumps, or pumping installations having flexible working members pumps or pumping installations specially adapted for elastic fluids F04B45/00
• CPC Class Codes: F04B 43/026 : each plate-like pumping flexible member working in its own pumping chamber
• CPC Class Codes: F04B 43/06 : Pumps having fluid drive
• CPC Class Codes: F04B 43/0736 : with two or more pumping chambers in parallel
• CPC Class Codes: F04B 45/02 : having bellows
• CPC Class Codes: F04B 45/0536 : the actuating fluid being controlled by one or more valves
• CPC Class Codes: F04B 49/02 : Stopping, starting, unloading or idling control
• CPC Class Codes: F04B 49/22 : by means of valves F04B49/03 takes precedence
• CPC Class Codes: F04B 53/06 : Venting
• CPC Class Codes: F04B 53/10 : Valves; Arrangement of valves
• CPC Class Codes: F04B 53/16 : Casings; Cylinders; Cylinder liners or heads; Fluid connections
• CPC Class Codes: F04B 7/02 : the valving being fluid-actuated
• CPC Class Codes: F04B 9/109 : having plural pumping chambers
• CPC Class Codes: F17D 3/00 : Arrangements for supervising or controlling working operations
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
• CPC Class Codes: Y10T 137/0324 : With control of flow by a condition or characteristic of a fluid
• CPC Class Codes: Y10T 137/0379 : By fluid pressure
• CPC Class Codes: Y10T 137/2521 : Flow comparison or differential response
• CPC Class Codes: Y10T 137/85978 : With pump
• CPC Class Codes: Y10T 137/86139 : Serial

Abstract

A pump cassette is disclosed. The pump cassette includes a housing having at least, one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump. The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.

Claims

1. A liquid handling pump cassette comprising:

a housing having a first plate spaced apart from a second plate, the first plate forming a first face of the housing and the second plate forming an opposing second face of the housing, and each plate having a corresponding perimeter defining one or more ends of the housing, the housing comprising;

a liquid inlet line positioned at an end of the housing and a liquid outlet line positioned at an end of the housing;

a first reciprocating membrane pump within said housing, said first pump being arranged to pump a first liquid from said liquid inlet line to said liquid outlet line via a first flow path within said housing;

a secondary fluid port on said housing, said secondary fluid port communicating through the first face of the housing with a second flow path in the housing; and

a second pump, said second pump being arranged to pump fluid through said secondary fluid port via the second flow path within the housing, wherein

said second flow path is in fluid communication with said liquid outlet line.

2. The cassette of claim 1, wherein said first reciprocating membrane pump comprises:

a chamber having a curved rigid chamber wall; and

a flexible membrane attached to an inner perimeter of said rigid chamber wall, wherein a first side of said flexible membrane and a first portion of said rigid chamber wall define a pumping chamber, and an opposing second side of said flexible membrane and a second portion of said rigid chamber wall define an actuation chamber.

3. The cassette of claim 2, wherein said second portion of the rigid chamber wall includes a control fluid port, said control fluid port being located on the second face of the housing.

4. The cassette of claim 2, wherein said actuation chamber includes a port for ingress or egress of control fluid.

5. The cassette of claim 4, wherein the second pump is a reciprocating membrane pump comprising a flexible membrane separating a liquid chamber from an actuation chamber, the liquid chamber being in fluid communication with the second flow path.

6. The cassette of claim 5, wherein the actuation chamber of the second pump includes a port for ingress or egress of control fluid.

7. The cassette of claim 6, wherein the ports of the actuation chambers of the first and second pumps are located on the second face of the housing.

8. The cassette of claim 1, further comprising an air vent in fluid communication with said second flow path.

9. The cassette of claim 8, further comprising an air filter connected to said air vent.

10. The cassette of claim 1, wherein said housing comprises a midplate positioned between the first and second plates.

11. The cassette of claim 1, further comprising:

a container holder for receiving and supporting a container containing a second liquid; and

a hollow spike within said container holder, said hollow spike being in fluid communication with the secondary fluid port of said housing.

12. The cassette of claim 1, further comprising at least one valve interposed between the first flow path and the liquid outlet of the housing.

13. The cassette of claim 12, wherein said at least one valve comprises a valve housing having a membrane, said membrane dividing said housing into an actuation chamber and a liquid chamber.

14. The cassette of claim 13, wherein said actuation chamber comprises at least one port and said liquid chamber comprises at least one port.

15. The cassette of claim 14, wherein said liquid chamber comprises two ports.

16. The cassette of claim 15, wherein an inner wall of said liquid chamber comprises a substantially smooth surface.

17. The cassette of claim 15, wherein a port in said liquid chamber is formed in a raised feature within the liquid chamber.

18. The cassette of claim 15, wherein said at least one valve is a volcano valve.

19. The cassette of claim 14, wherein said at least one port of said actuation chamber is located on the second face of the housing.

20. The cassette of claim 1, wherein the secondary fluid port is in fluid communication with the liquid outlet line via a first valve between the secondary fluid port and the second flow path, and via a second valve between the second flow path and the liquid outlet line.

21. The cassette of claim 20, further comprising an air vent located on the first face of the housing, wherein the air vent is in fluid communication with the second flow path via a third valve in the housing.

22. The cassette of claim 21, wherein the first, second and third valves each comprises a valve housing having a membrane, said membrane dividing said housing into an actuation chamber and a liquid chamber.

23. The cassette of claim 22, wherein each actuation chamber of the first, second and third valves includes a port for ingress or egress of control fluid, and wherein each port is located on the second face of the housing.

27. The cassette of claim 1, wherein said first liquid inlet line is positioned at a first end of the housing and wherein said liquid outlet line is positioned at a second end of the housing.

24. A liquid handling pump cassette comprising:

a housing having a first plate spaced apart from a second plate, the first plate forming a first face of the housing and the second plate forming an opposing second face of the housing, and each plate having a corresponding perimeter defining one or more ends of the housing, the housing comprising;

a first liquid inlet line positioned at an end of the housing and a liquid outlet line positioned at an end of the housing;

a first reciprocating membrane pump within said housing, first pump being arranged to pump a first liquid from said first liquid inlet line to said liquid outlet line via a first flow path within said housing;

a second flow path within said housing, said second flow path being in fluid communication with the first flow path and comprising;

a metering membrane pump;

a second liquid inlet line for pumping a volume of a second liquid into said liquid outlet line, said second liquid inlet line entering the housing through the first face of said housing;

a hollow spike in fluid communication with said second liquid inlet line; and

an air vent in fluid communication with said second liquid inlet line, wherein

said metering membrane pump is configured to infuse a quantity of a second liquid via the hollow spike into the first flow path.

25. The cassette of claim 24, wherein said reciprocating membrane pump comprises:

a chamber having a curved rigid chamber wall; and

a flexible membrane attached to an inner perimeter of said rigid chamber wall, wherein a first side of said flexible membrane and a first portion of said rigid chamber wall define a pumping chamber, and an opposing second side of said flexible membrane and a second portion of said rigid chamber wall define an actuation chamber.

26. The cassette of claim 24, wherein said housing comprises a midplate positioned between the first and second plates.

28. The cassette of claim 24, wherein said first liquid inlet line is positioned at a first end of the housing and wherein said liquid outlet line is positioned at a second end of the housing.

29. A liquid handling pump cassette comprising:

a housing having a first plate spaced apart from a second plate, the first plate forming a first face of the housing and the second plate forming an opposing second face of the housing, and each plate having a corresponding perimeter defining one or more ends of the housing, the housing comprising;

a first liquid inlet line positioned at an end of the housing and a liquid outlet line positioned at an end of the housing;

a first reciprocating membrane pump within said housing, said first pump being arranged to pump a first liquid from said first liquid inlet line to said liquid outlet line via a first flow path within said housing;

a second flow path within said housing, said second flow path being in fluid communication via a first valve with the first flow path and comprising;

a metering membrane pump;

a second liquid inlet line for pumping a volume of a second liquid into the liquid outlet line, the second liquid inlet line entering the housing through the first face of the housing and in fluid communication with the second flow path via a second valve;

a hollow spike in fluid communication with the second liquid inlet line; and

an air vent in fluid communication with the second flow path via a third valve, wherein

the metering membrane pump is configured to infuse a quantity of a second liquid via the hollow spike into the first flow path.

30. The cassette of claim 29, wherein said first liquid inlet line is positioned at a first end of the housing and wherein said liquid outlet line is positioned at a second end of the housing.

31. The cassette of claim 29, wherein the metering membrane pump is configured to infuse a quantity of a second liquid from a closed container spiked onto the hollow spike.

32. The cassette of claim 29, wherein the first reciprocating membrane pump, the metering membrane pump, and the valves each comprises a flexible membrane separating a liquid handling chamber from an actuation chamber, each actuation chamber including a port for ingress or egress of control fluid, and each port being located on the second face of the housing.