Wear-resistant electrochemical test sensor and method of forming the same

• US 8,273,226 B2
• Filed: 12/09/2008
• Issued: 09/25/2012
• Est. Priority Date: 12/10/2007
• Status: Active Grant

• Current Assignee: Ascensia Diabetes Care Holdings AG (PHC Holdings Corporation)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Edelbrock, Andrew J.
• Primary Examiner(s): Noguerola, Alex
• Assistant Examiner(s): Kaur, Gurpreet
• Application Number:
  US12/316,113
• Publication Number:
  US 20090145755A1
• Time in Patent Office: 1,386 Days
• Field of Search: 204/403.01, 204/403.04, 204/403.09, 204/403.11, 204/403.14, 204/192.3, 204/192.32, 204/192.1, 204/192.11, 204/400, 205/777.5, 205/778, 205/792, 600345-348, 435 4- 4052, 422 681- 98, 436 62- 71, 436500-548
• US Class Current: 204/400
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: Y10T 156/1082 Partial cutting bonded sandwich [e.g., grooving or incising]

Abstract

An electrochemical test sensor includes a base, a generally hard electrically-conductive layer, an electrochemically-active layer, and a lid. The electrically-conductive layer is located between the base and the electrochemically-active layer. The electrically-conductive layer and the electrochemically-active layer are made of a different material. The electrically-conductive layer and the electrochemically-active layer form an electrode pattern. The electrochemical test sensor includes a reagent adapted to assist in determining information related to an analyte of a fluid sample.

Claims

1. An electrochemical test sensor comprising a base, a conductive layer comprising indium tin oxide, an electrochemically-active layer, and a lid, the conductive layer being located between the base and the electrochemically-active layer, the conductive layer and the electrochemically-active layer being made of a different material, the conductive layer and the electrochemically-active layer forming a plurality of electrodes, a plurality of conductive leads and a plurality of test-sensor contacts, and wherein the electrochemical test sensor includes a reagent adapted to assist in determining information related to an analyte of a fluid sample.

2. The test sensor of claim 1, further including a spacer, the spacer and the lid assisting in forming a channel in which to receive the fluid, the channel including the reagent.

3. The test sensor of claim 1, wherein the electrochemically-active layer includes gold, platinum, rhodium, palladium, ruthenium or combinations thereof.

4. The test sensor of claim 1, wherein the reagent includes glucose oxidase or glucose dehydrogenase.

5. An electrochemical test sensor comprising a base, a conductive layer including indium zinc oxide, an electrochemically-active layer and a lid, the conductive layer being located between the base and the electrochemically-active layer, the conductive layer being made of a different material than the electrochemically-active layer, the conductive layer and the electrochemically-active layer forming a plurality of electrodes, a plurality of conductive leads and a plurality of test-sensor contacts, and wherein the electrochemical test sensor includes a reagent adapted to assist in determining information related to an analyte of a fluid sample.

6. The test sensor of claim 5, further including a spacer, the spacer and the lid assisting in forming a channel in which to receive the fluid, the channel including the reagent.

7. The test sensor of claim 5, wherein the electrochemically-active layer includes gold, platinum, rhodium, palladium, ruthenium or combinations thereof.

8. The test sensor of claim 5, wherein the reagent includes glucose oxidase or glucose dehydrogenase.

9. A method of forming an electrochemical test sensor, the method comprising the acts of:

providing a base;

placing a conductive layer on the base, the conductive layer including indium tin oxide;

placing an electrochemically-active layer on the conductive layer, the electrochemically-active layer being made of a different material than the conductive layer;

forming the electrochemically-active layer and the conductive layer into a plurality of electrodes, a plurality of conductive leads and a plurality of test-sensor contacts; and

applying a second layer to assist in forming a channel in the test sensor, the channel assisting in allowing a fluid sample to contact a reagent located therein.

10. The method of claim 9, wherein the forming of the plurality of electrodes includes the use of laser-ablating.

11. The method of claim 9, wherein the second layer is a lid.

12. The method of claim 9, wherein the second layer is a spacer and further includes applying a lid to the spacer so as to define the channel, the spacer being located between the lid and the base.

13. The method of claim 12, wherein the channel is a capillary channel.

14. The method of claim 9, wherein the plurality of electrodes is formed by printing, coating, vapor deposition, sputtering or electrochemical deposition.

15. The method of claim 9, wherein the electrochemically-active layer includes gold, platinum, rhodium, palladium, ruthenium or combinations thereof.

16. The method of claim 9, wherein the reagent includes glucose oxidase or glucose dehydrogenase.

17. A method of forming an electrochemical test sensor, the method comprising the acts of:

providing a base;

placing a conductive layer on the base, the conductive layer including indium zinc oxide;

placing an electrochemically-active layer on the conductive layer, the electrochemically-active layer being made of a different material than the conductive layer;

forming the electrochemically-active layer and the conductive layer into a plurality of electrodes, a plurality of conductive leads and a plurality of test-sensor contacts; and

applying a second layer to assist in forming a channel in the test sensor, the channel assisting in allowing a fluid sample to contact a reagent located therein.

18. The method of claim 17, wherein the forming of the plurality of electrodes includes the use of laser-ablating.

19. The method of claim 17, wherein the second layer is a lid.

20. The method of claim 17, wherein the second layer is a spacer and further includes applying a lid to the spacer so as to define the channel, the spacer being located between the lid and the base.

21. The method of claim 20, wherein the channel is a capillary channel.

22. The method of claim 17, wherein the plurality of electrodes is formed by printing, coating, vapor deposition, sputtering or electrochemical deposition.

23. The method of claim 17, wherein the electrochemically-active layer includes gold, platinum, rhodium, palladium, ruthenium or combinations thereof.

24. The method of claim 17, wherein the reagent includes glucose oxidase or glucose dehydrogenase.