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Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue

  • US 8,280,504 B2
  • Filed: 04/01/2005
  • Issued: 10/02/2012
  • Est. Priority Date: 05/20/2002
  • Status: Expired due to Fees
First Claim
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1. A method for determining a condition of ductal epithelial tissue of the breast comprising:

  • (A) placing at least one current-passing electrode in contact with or in proximity to a surface of the breast, at least one of said current-passing electrode is in electrical communication with said ductal epithelium;

    (B) placing a plurality of measuring electrodes in contact with or in proximity to said surface;

    (C) establishing an electrical signal between said at least one current-passing electrode and at least one of said measuring electrodes;

    (D) measuring, at one or more of said measuring electrodes, an impedance associated with said signal;

    (E) introducing at least one agent into said ductal epithelial tissue so as to instantaneously reveal and accentuate changes in impedance in said ductal epithelial tissue and measuring, at one or more of said measuring electrodes, an impedance associated with said signal following the introduction of said at least one agent; and

    (F) determining the condition of said ductal epithelial tissue based on said impedance.

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