Image handling and display in x-ray mammography and tomosynthesis

• US 8,285,020 B2
• Filed: 02/15/2011
• Issued: 10/09/2012
• Est. Priority Date: 11/27/2002
• Status: Expired due to Term

• Current Assignee: Hologic Incorporated
• Original Assignee: Hologic Incorporated
• Inventors: Gkanatsios, Nikolaos A., Niklason, Loren, Shaw, Ian, Ruth, Christopher, Smith, Andrew P., Stein, Jay A.
• Primary Examiner(s): Bayat, Ali
• Application Number:
  US13/027,771
• Publication Number:
  US 20110135185A1
• Time in Patent Office: 602 Days
• Field of Search: 382/128, 382/131, 382/132, 378/23, 378/37, 378/68, 378/154, 378/152, 378/163, 378/165, 378/101
• US Class Current: 382/128
• CPC Class Codes: A61B 6/025 Tomosynthesis
• CPC Class Codes: A61B 6/463 characterised by displaying multiple images or images and diagnostic data on one display
• CPC Class Codes: A61B 6/464 involving a plurality of displays
• CPC Class Codes: A61B 6/465 adapted to display user selection data, e.g. graphical user interface, icons or menus
• CPC Class Codes: A61B 6/502 for diagnosis of breast, i.e. mammography
• CPC Class Codes: G06F 3/04855 Interaction with scrollbars
• CPC Class Codes: G06T 11/006 Inverse problem, transformation from projection-space into object-space, e.g. transform methods, back-projection, algebraic methods
• CPC Class Codes: G06T 2200/24 involving graphical user interfaces [GUIs]
• CPC Class Codes: G06T 2207/10112 Digital tomosynthesis [DTS]
• CPC Class Codes: G06T 2207/20068 Projection on vertical or horizontal image axis
• CPC Class Codes: G06T 2207/30068 Mammography; Breast
• CPC Class Codes: G06T 7/0012 Biomedical image inspection

Abstract

A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images.

Claims

1. A tomosynthesis system comprising an anti-scatter grid that remains focused on the x-ray source in at least one dimension of the grid, said system further comprising:

an x-ray source selectively emitting an imaging x-ray beam, a breast immobilizing structure defining a volume for a patient'"'"'s breast, and an x-ray imaging receptor arranged such that said x-ray beam passes first through said volume and then through said anti-scatter grid before impinging on said imaging receptor;

a source support mounting said x-ray source for selective movement relative to the breast immobilizing structure;

an x-ray data acquisition control configured to;

cause the x-ray source to move through a plurality of different imaging positions relative to the breast immobilizing structure and selectively illuminate said imaging receptor with said x-ray beam, and

cause said imaging receptor to provide imaging data in response to being illuminated with said x-ray beam for said different imaging positions;

wherein said anti-scatter grid remains focused on the x-ray source in at least one dimension of the grid while said x-ray source is moving through said different imaging positions;

a processing and image reconstruction unit configured to receive and process said imaging data and obtain a plurality of projection images Tp and a plurality of reconstructed slices images Tr, wherein;

each image Tp is a projection x-ray image of said volume taken with said x-ray beam for a respective one of said plurality of different positions of the x-ray source relative to the breast immobilizing structure; and

each image Tr is an image of a respective 3-dimensional slice of said volume reconstructed through computer processing using at least several of said projection images Tp; and

an image display unit configured to selectively display one or more of said slice images Tr and projection images Tp.

2. The system of claim 1 in which said anti-scatter grid remains focused on the x-ray source in each of two dimensions of the grid while the x-ray source is moving through said different positions.

3. The system of claim 1 in which the anti-scatter grid moves relative to said breast immobilizing structure while the x-ray source is moving through said imaging positions.

4. The system of claim 1 in which said motion of the x-ray source through said imaging positions is intermittent, and wherein the x-ray source emits said imaging x-ray beam while stopped in the course of said intermittent motion.

5. The system of claim 1 in which said motion of the x-ray source through said imaging positions is continuous and the x-ray source emits said imaging beam while moving.

6. The system of claim 1 in which said image display is configured to concurrently display two or more of said images.

7. The system of claim 6 in which said image display is configured to concurrently display two or more of said slice images Tr.

8. The system of claim 6 in which said image display is configured to concurrently display two or more of said projection images Tp.

9. The system of claim 6 in which said image display is configured to concurrently display at least one image Tp and at least one image Tr.

10. The system of claim 6 in which said processing and image reconstruction unit is further configured to generate information defining an image analogous to a superposition of multiple ones of said 3-dimensional slice images Tr.

11. The system of claim 10 in which said display is configured to display said analogous image concurrently with displaying at least one of said images Tp and Tr.

12. The system of claim 1 in which said analogous image is a mammogram projection image Mp of said volume.

13. The system of claim 12 in which the system obtains said image Mp by illuminating the imaging receptor using a higher x-ray dose than for one of said images Tp.

14. The system of claim 12 in which said display unit is configure to concurrently display said image Mp and at least one of said images Tp and Tr.

15. The system of claim 1 in which said processing and image reconstruction unit is configured to process said imaging data to obtain CAD information and said display unit is configured to display CAD marks related to said CAD information while concurrently displaying one or more of said images Tp and Tr.

16. The system of claim 1 in which said display unit is configured to concurrently display two images Tr representing slices of said volume extending along respective planes that are at a stereotactic angle to each other.

17. The system of claim 1 in which said display unit is configured to concurrently display two images Tp representing projections of said volume taken from respective imaging positions of said x-ray source that are separated from each other by at least one other imaging position.

18. A system as in claim 1 in which said imaging positions of the x-ray source include an imaging position that is intermediate a position vertically above and horizontally to the side of said volume.

19. A system as in claim 1 in which the imaging positions of the x-ray source include an imaging position in which the imaging x-ray beam is oriented in substantially the same way as in an MLO orientation in conventional mammography.

20. A system as in claim 1 in which said at least one dimension of the grid is parallel to a plane in which the x-ray source moves through said imaging positions.

21. A method of imaging a patient'"'"'s breast with x-rays comprising:

selectively emitting an imaging x-ray beam that passes through a patient'"'"'s breast immobilized in a breast immobilizing structure and then through an anti-scatter grid before impinging on an x-ray imaging receptor;

moving the x-ray source through a plurality of different imaging positions relative to the breast immobilizing structure and selectively energizing the source to illuminate said imaging receptor with said x-ray beam;

obtaining imaging data from the imaging receptor in response to illumination thereof with said x-ray beam for said different imaging positions;

maintaining said anti-scatter grid focused on the x-ray source in at least one dimension of the grid while said x-ray source is moving through said imaging positions;

computer-processing said imaging data to generate a plurality of images Tp and a plurality of images Tr, wherein each image Tp is a projection x-ray image of the patient'"'"'s breast taken with said x-ray beam for a respective one of said plurality of imaging positions of the x-ray source relative to the breast immobilizing structure, and each image Tr is an image of a respective 3-dimensional slice of the patient'"'"'s breast reconstructed through computer processing using at least several of said images Tp; and

selectively displaying one or more of said slice images Tr and projection images Tp.

22. The method of claim 21 including maintaining said anti-scatter grid focused on the x-ray source in each of two dimensions of the grid while the x-ray source is moving through said different positions.

23. The method of claim 21 including moving the anti-scatter grid relative to said breast immobilizing structure while the x-ray source is moving through said imaging positions.

24. The method of claim 21 in which said motion of the x-ray source through said imaging positions is intermittent, and wherein the x-ray source emits said imaging x-ray beam while stopped in the course of said intermittent motion.

25. The method of claim 21 in which said motion of the x-ray source through said imaging positions is continuous and the x-ray source emits said imaging beam while moving.

26. The method of claim 21 including concurrently displaying two or more of said images Tr.

27. The method of claim 21 including concurrently displaying two or more of said images Tp.

28. The method of claim 21 including concurrently display at least one image Tp and at least one image Tr.

29. The method of claim 21 including generating information defining an image analogous to a superposition of multiple ones of said images Tr.

30. The method of claim 29 including displaying said analogous image concurrently with displaying at least one of said images Tp and Tr.

31. The method of claim 21 in which said analogous image is a mammogram projection image Mp of the patient'"'"'s breast.

32. The method of claim 21 including obtaining said image Mp by illuminating the imaging receptor using a higher x-ray dose than for one of said images Tp.

33. The method of claim 21 including obtaining CAD information and displaying CAD marks related to said CAD information while concurrently displaying one or more of said images Tp and Tr.

34. The method of claim 21 including concurrently displaying two images Tr representing slices of the patient'"'"'s breast extending along respective planes that are at a stereotactic angle to each other.

35. The method of claim 21 including concurrently displaying two images Tp representing projections of the patient'"'"'s breast taken from respective imaging positions of the x-ray source that are separated from each other by at least one other imaging position.

36. A method as in claim 21 in which said imaging positions of the x-ray source include an imaging position in which the imaging x-ray beam is oriented in substantially the same way as in an MLO orientation in conventional mammography.

37. A method as in claim 21 in which said at least one dimension of the grid is parallel to a plane in which the x-ray source moves through said imaging positions.

38. A method of providing and displaying x-ray images of a patient'"'"'s breast comprising:

obtaining x-ray imaging data describing a plurality of images Tp and a plurality of

images Tr, wherein each image Tp relates to a projection x-ray image of the patient'"'"'s breast taken for a respective one of said plurality of imaging positions of relative to an immobilized patient'"'"'s breast and each image Tr relates to an image of a respective 3-dimensional slice of the patient'"'"'s breast reconstructed through computer processing using at least several of said images Tp;

generating CAD information related to suspected abnormalities in at least one of said images Tp and Tr;

selectively displaying concurrently at least two of said images Tr and images Tp; and

selectively displaying, concurrently with the display of at least two of said images Tr and Tp, CAD marks related to said CAD information and associated with at least one of the displayed images.

39. The method of claim 38 in which at least one of the displayed CAD marks relates to CAD information derived from an image of the patient'"'"'s breast that is different from the concurrently displayed images of the breast.

40. The method of claim 38 including obtaining an image Mp related to a mammogram of the patient'"'"'s breast derived by irradiating the breast with a higher dose of x-rays than for one of said images Tp and selectively displaying the image Mp concurrently with the display of at least two of said images Tp and Tr.

41. The method of claim 38 including providing an anti-scatter grid between the patient'"'"'s breast and an imaging receptor from which said imaging data is obtained, said grid remaining focused on a source of imaging x-rays along at least one dimension of the grid while said projection images are taken.