Automated pipetting apparatus having a combined liquid pump and pipette head system
First Claim
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1. A liquid dispenser, comprising:
- a gas manifold comprising a plurality of independently controllable manifold valves and a plurality of lines configured to distribute gas amongst the plurality of manifold valves;
one or more pumps configured to provide gas to the gas manifold;
a plurality of dispense heads each in fluid communication with the gas manifold and configured to receive gas from one of said manifold valves; and
electrical connections configured to transmit control signals from an external controller to the gas manifold for independent operation of each of the plurality of manifold valves,wherein each of the plurality of manifold valves is configured to be individually regulated to selectably divert gas from the one or more pumps to one of the plurality of dispense heads.
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Abstract
The technology described herein generally relates to systems for extracting polynucleotides from multiple samples, particularly from biological samples, and additionally to systems that subsequently amplify and detect the extracted polynucleotides. The technology more particularly relates to microfluidic systems that carry out PCR on multiple samples of nucleotides of interest within microfluidic channels, and detect those nucleotides. The technology still more particularly relates to automated devices for carrying out pipetting operations, particularly on samples in parallel, consistent with sample preparation and delivery of PCR-ready nucleotide extracts to a cartridge wherein PCR is run.
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20 Claims
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1. A liquid dispenser, comprising:
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a gas manifold comprising a plurality of independently controllable manifold valves and a plurality of lines configured to distribute gas amongst the plurality of manifold valves; one or more pumps configured to provide gas to the gas manifold; a plurality of dispense heads each in fluid communication with the gas manifold and configured to receive gas from one of said manifold valves; and electrical connections configured to transmit control signals from an external controller to the gas manifold for independent operation of each of the plurality of manifold valves, wherein each of the plurality of manifold valves is configured to be individually regulated to selectably divert gas from the one or more pumps to one of the plurality of dispense heads. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification