Formulation for hair growth

• US 8,288,366 B2
• Filed: 06/20/2006
• Issued: 10/16/2012
• Est. Priority Date: 06/20/2006
• Status: Active Grant

• Current Assignee: Martha Gonzalez, Ronald H. Chochinov
• Original Assignee: Martha Gonzalez, Ronald H. Chochinov
• Inventors: Chochinov, Ronald H., Gonzalez, Martha
• Primary Examiner(s): CLAYTOR, DEIRDRE RENEE
• Application Number:
  US11/471,827
• Publication Number:
  US 20070292538A1
• Time in Patent Office: 2,310 Days
• Field of Search: 514/169, 514/171
• US Class Current: 514/169
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/197 the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid carnitine A61K31/205
• CPC Class Codes: A61K 31/565 not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
• CPC Class Codes: A61P 17/14 for baldness or alopecia

Abstract

A composition and method for hair growth are described. The composition may include a dihydrotestosterone blocker and a thyroid source. Alternatively, the composition may include an estrogen source and a thyroid source. The composition may further include a base to facilitate application of the composition. A progestagen source, an antioxidant and/or a vitamin may further be added to the composition. The method may be a method of application comprising applying 0.5 ounces of a composition comprising a dihydrotestosterone blocker and a thyroid source to human skin, rubbing the composition into the skin, allowing the composition to remain on the skin for a period of between five minutes and ten minute and removing the composition.

Claims

1. A method of application comprising:

applying 0.5 ounces of a shampoo composition comprising a dihydrotestosterone blocker and a thyroid source to human skin once a day;

rubbing the shampoo composition into the skin;

allowing the shampoo composition to remain on the skin for a period of between five minutes and ten minutes; and

removing the shampoo composition, wherein the amounts of the dihydrotestosterone blocker and the thyroid source are selected to treat alopecia without a clinically significant absorption of the dihydrotestosterone blocker or the thyroid source.

2. The method of claim 1, wherein the dihydrotestosterone blocker is an estrogen source.

3. The method of claim 2, wherein the estrogen source is estradiol.

4. The method of claim 1, wherein the thyroid source is a thyroid hormone.

5. The method of claim 4, wherein the thyroid hormone is triiodothyronine.

6. The method of claim 1, wherein the shampoo composition comprises approximately 100 mg of the dihydrotestosterone blocker.

7. The method of claim 1, wherein the shampoo composition comprises approximately 100 μ

g of the thyroid source.

8. The method of claim 1, further comprising a base suitable for application to human skin.

9. The method of claim 1, further comprising a progestagen source.

10. The method of claim 9, wherein the progestagen source is one of progesterone and synthetic progestin.

11. The method of claim 1, further comprising one of an antioxidant and a vitamin.

12. The method of claim 1, where the composition includes liposomes.

19. The method of claim 1 wherein the dihydrotestosterone blocker is saw palmetto.

20. The method of claim 1 wherein the dihydrotestosterone blocker is an estrogen source selected from the group consisting of estradiol-17-beta, estradiol valerate, conjugated equine estrogens, piperazine estrone sulphate, estrone, estriol, estriol succinate and polyestriol phosphate.

21. The method of claim 1 wherein the thyroid source is a synthetic thyroid hormone selected from the group consisting of dessicated porcine thyroid, levothyroxine, liothyronine and liotrix.

13. A method of treating alopecia comprising:

applying 0.5 ounces to one ounce of a shampoo composition comprising a dihydrotestosterone blocker and a thyroid source to human skin once a day;

rubbing the shampoo composition into the skin;

allowing the shampoo composition to remain on the skin for a period of between five minutes and ten minutes; and

removing the shampoo composition,

wherein the amounts of the dihydrotestosterone blocker and the thyroid source are selected to treat alopecia without a clinically significant absorption the dihydrotestosterone blocker or the thyroid source.

14. The method of claim 13, wherein the dihydrotestosterone blocker is an estrogen source.

15. The method of claim 13, wherein the composition further comprises a progestagen source.

16. The method of claim 13, wherein the composition further comprises one of an antioxidant and a vitamin.

17. A method of treating alopecia comprising:

applying 0.5 ounces to one ounce of a shampoo composition comprising an estrogen source and a thyroid source to human skin once a day;

rubbing the shampoo composition into the skin;

allowing the shampoo composition to remain on the skin for a period of between five minutes and ten minutes; and

removing the shampoo composition wherein the amounts of the estrogen source and the thyroid source are selected to treat alopecia without a clinically significant absorption of the estrogen source or the thyroid source.

18. The method of claim 17, wherein the composition further comprises a progestagen source.