Arrangements and methods for providing multimodality microscopic imaging of one or more biological structures
First Claim
1. An apparatus comprising:
- a light source emitting an electro-magnetic radiation; and
at least one arrangement configured to provide (i) first data associated with a first signal received from at least one region of at least one sample based on a first modality, (ii) second data associated with a second signal received from the at least one sample based on a second modality which is different from the first modality, and (iii) at least one third data associated with a third signal received from the at least one sample, wherein each of the at least one third data is based on a third modality which is different from the first modality and the second modality,wherein the first, second and third signals are generated by the electro-magnetic radiation emitted by the light source.
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Abstract
Method and apparatus according to an exemplary embodiment of the present invention can be provided. For example, first data associated with a first signal received from at least one region of at least one sample can be provided based on a first modality, and second data associated with a second signal received from the at least one sample can be provided based on a second modality which is different from the first modality. Third data associated with a reference can be received. Further data can be generated based on the first, second and third data. In addition, third data associated with a second signal received from the at least one sample can be obtained. Each of the third data can be based on a further modality which is different from the first modality and the second modality, and the further data can be further determined based on the third data. Further, the first modality can be a spectral-encoded modality, and the second modality can be a non-spectral-encoding modality.
618 Citations
22 Claims
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1. An apparatus comprising:
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a light source emitting an electro-magnetic radiation; and at least one arrangement configured to provide (i) first data associated with a first signal received from at least one region of at least one sample based on a first modality, (ii) second data associated with a second signal received from the at least one sample based on a second modality which is different from the first modality, and (iii) at least one third data associated with a third signal received from the at least one sample, wherein each of the at least one third data is based on a third modality which is different from the first modality and the second modality, wherein the first, second and third signals are generated by the electro-magnetic radiation emitted by the light source. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. An apparatus comprising:
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a light source emitting an electro-magnetic radiation; and at least one arrangement configured to provide (i) first data associated with a first signal received from at least one region of at least one sample based on a spectral-encoding first modality, and (ii) second data associated with a second signal received from the at least one sample based on a non-spectral-encoding second modality, wherein the first and second signals are generated by the electro-magnetic radiation emitted by the light source. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20)
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21. A method comprising:
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emitting an electro-magnetic radiation using a light source arrangement; and providing (i) first data associated with a first signal received from at least one region of at least one sample based on a first modality, (ii) second data associated with a second signal received from the at least one sample based on a second modality which is different from the first modality, and (iii) at least one third data associated with a third signal received from the at least one sample, wherein each of the at least one third data is based on a third modality which is different from the first modality and the second modality, wherein the first and second signals are generated by the electro-magnetic radiation emitted by the light source.
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22. A method comprising:
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emitting an electro-magnetic radiation using a light source arrangement; and providing (i) first data associated with a first signal received from at least one region of at least one sample based on a spectral-encoding first modality, and (ii) second data associated with a second signal received from the at least one sample based on a non-spectral-encoding second modality, wherein the first and second signals are generated by the electro-magnetic radiation emitted by the light source.
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Specification