Dynamic morphology based atrial automatic threshold

• US 8,290,590 B2
• Filed: 11/17/2006
• Issued: 10/16/2012
• Est. Priority Date: 11/17/2006
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Bohn, Derek D., Garg, Ankur, Enrooth, Eric K.
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): KIMBALL, JEREMIAH T
• Application Number:
  US11/601,217
• Publication Number:
  US 20080119905A1
• Time in Patent Office: 2,160 Days
• Field of Search: 607/28
• US Class Current: 607/28
• CPC Class Codes: A61N 1/371 Capture, i.e. successful stimulation
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

Methods and systems for performing capture threshold tests are described. During an initialization procedure a capture detection interval and capture detection threshold are determined based on peak values of cardiac signals sensed following the supracapture threshold initialization pulses. Following initialization, a plurality of pacing pulses to the atrium are delivered and the peak values of the cardiac signals sensed following each of the plurality of pacing pulses are determined. The peak values are compared to the pacing artifact threshold and the capture detection threshold. A timing of each of the peak values is compared to the capture detection interval. For each pacing pulse, discrimination between a captured response, a noncaptured response, and a fusion response is based on the peak value and timing comparisons.

Claims

1. An implantable cardiac rhythm management system, comprising:

a control processor configured to control delivery of atrial pacing pulses via a pulse generator;

a sensing circuit configured to sense a cardiac signal following an atrial pacing pulse; and

a pacing response classification processor configured to detect a peak of the cardiac signal and to discriminate between capture, noncapture, and fusion in the atrium based on a position of the peak in relation to regions characterized by a capture detection time interval, a capture detection amplitude threshold, and a pacing artifact amplitude threshold.

2. The system of claim 1, wherein the pacing response classification processor is configured to adjust the capture detection amplitude threshold using a cardiac signal classified as an evoked response.

3. The system of claim 1, wherein the pacing response classification processor is configured to adjust the pacing artifact amplitude threshold using a cardiac signal classified as a noncaptured response.

4. The system of claim 1, wherein:

the control processor is configured to control delivery of pacing pulses during a capture threshold test; and

the pacing response classification processor is configured to assign one or more pacing response values, the one or more response values respectively associated with one or more likely cardiac responses to the pacing pulse, based on the position of the peak of the cardiac signal to one or more regions bounded by the capture detection amplitude threshold and the pacing amplitude artifact threshold, each of the response values associated with capture, noncapture or fusion.

5. The system of claim 4, wherein the one or more pacing response values comprises a fractional value.

6. The system of claim 4, wherein at least one function of the capture threshold test is performed based on the response values.

7. The system of claim 4, wherein the pacing response classification processor is configured to confirm loss of capture based on a sum of response values associated with noncapture.

8. The system of claim 4, wherein the control processor is configured to modify a pacing energy or pacing rate of the capture threshold test based on a sum of response values associated with capture.

9. The system of claim 1, wherein the peak of the cardiac signal is associated with a peak magnitude and a peak timing.

10. The system of claim 9, wherein the pacing response classification processor is configured to compare a position of the peak timing to one or more regions bounded by the capture detection time interval, and to compare a position of the peak amplitude to one or more regions bounded by the capture detection amplitude threshold and the pacing artifact amplitude threshold.

11. The system of claim 10, wherein the pacing response classification processor is configured to discriminate between capture, noncapture, and fusion in the atrium based on both the comparison of a position of the peak timing to one or more regions bounded by the capture detection time interval, and the comparison of a position of the peak amplitude to one or more regions bounded by the capture detection amplitude threshold and the pacing artifact amplitude threshold.

12. The system of claim 1, wherein the pacing response classification processor is further configured to determine the capture detection time interval during an initialization procedure.

13. The system of claim 1, wherein the pacing response classification processor is further configured to determine the capture detection amplitude threshold during an initialization procedure.

14. The system of claim 1, wherein the pacing response classification processor is further configured to determine the capture detection time interval, the capture detection amplitude threshold, and the pacing artifact amplitude threshold during an initialization procedure.

15. The system of claim 14, wherein the pacing response classification processor is configured to determine the capture detection time interval based on peak timing values of cardiac signals sensed following supracapture threshold initialization pulses.

16. The system of claim 14, wherein the pacing response classification processor is configured to determine the capture detection amplitude threshold based on peak amplitude values of cardiac signals sensed following supracapture threshold initialization pulses.

17. The system of claim 14, wherein the pacing response classification processor is configured to determine the pacing artifact amplitude threshold based on peak magnitude values of cardiac signals associated with noncapture.

18. An implatable cardiac rhythm management system, comprising:

a pulse generator;

a control processor configured to control delivery of an atrial pacing pulse via the pulse generator;

a sensing circuit configured to sense a cardiac signal following the atrial pacing pulse and to detect a peak of the sensed cardiac signal, the peak having a peak timing and a peak amplitude;

a classification unit configured to determine a cardiac response to the atrial pacing pulse based on a position of the peak in relation to regions characterized by a capture detection timing interval, a capture detection amplitude threshold, and a pacing artifact amplitude threshold.

19. The system of claim 18, wherein the classification unit is configured to discriminate between capture, noncapture, and fusion based on the comparisons.