Slide-and-lock stent

• US 8,292,944 B2
• Filed: 12/17/2004
• Issued: 10/23/2012
• Est. Priority Date: 12/17/2004
• Status: Expired due to Fees

• Current Assignee: REVA Medical Inc.
• Original Assignee: REVA Medical Inc.
• Inventors: Schmid, Eric V., Nguyen, John D., Howard, Steven C., Padilla, Orlando M., Morris, Andrew, Eisele, Robert F., DiPari, Joseph Anthony, Matsuura, David G., Simpson, Philip J., Gillespie, Walter D., Moore, Daniel, Jackson, Thomas R., Zeltinger, Joan, Esser, Keith Allen, Brandom, Donald K.
• Primary Examiner(s): HOLWERDA, KATHLEEN SONNETT
• Application Number:
  US11/016,269
• Publication Number:
  US 20060136041A1
• Time in Patent Office: 2,867 Days
• Field of Search: 623 111- 123, 245/931.1, 246/16, 606/194, 606/200
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/92 Stents in the form of a rolled-up sheet expanding after insertion into the vessel , e.g. with a spiral shape in cross-section
• CPC Class Codes: A61F 2/93 circumferentially expandable by using ratcheting locks
• CPC Class Codes: A61F 2210/0076 multilayered, e.g. laminated structures
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: B33Y 80/00 Products made by additive manufacturing

Abstract

The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter.

Claims

1. A slide-and-lock stent comprising:

at least two circumferentially adjacent radial elements, each radial element comprising an elongate rail, a closed loop, and a neck portion disposed between the elongate rail and the closed loop, the elongate rail comprising a deflectable tooth, the closed loop disposed at one end of the elongate rail and defining an engagement slot, wherein the neck portion is narrower than the elongate rail and the closed loop, and wherein the engagement slot from one radial element is sized to accommodate the closed loop from a circumferentially adjacent radial element, thereby allowing assembly of the at least two circumferentially adjacent radial elements without welding or bonding,

wherein the engagement slot from said one radial element is further configured to slidably engage the elongate rail of said circumferentially adjacent radial element and to cause the deflectable tooth of the slidably engaged elongate rail to deflect as it passes therethrough such that said stent achieves expansion in a circumferential axis with reduced recoil.

2. The slide-and-lock stent of claim 1, wherein each elongate rail further comprises two rail members with a gap therebetween, such that the rail members are configured to deflect toward one another into the gap when engaged by said slot.

3. The slide-and-lock stent of claim 1, wherein each elongate rail has a plurality of deflectable teeth disposed thereon.

4. The slide-and-lock stent of claim 1, further comprising a first module comprising more than one radial element, linked to one another in a longitudinal axis of the stent, and a second module comprising more than one circumferentially adjacent radial element, linked to one another in the longitudinal axis.

5. The slide-and-lock stent of claim 4, wherein the longitudinally linked radial elements in each module are circumferentially offset from one another in a zig-zig pattern.

6. The slide-and-lock stent of claim 4, wherein the longitudinally linked first radial elements are connected to one another by at least a first flexible linkage element, and the longitudinally linked second radial elements are connected to one another by at least a second flexible linkage element.

7. The slide-and-lock stent of claim 1, wherein a cross-sectional geometry of at least a portion of the stent is tapered so as to produce generally uniform blood flow characteristics when the stent is placed in a blood vessel lumen.

8. The slide-and-lock stent of claim 1, wherein the stent further comprises a material selected from the group consisting of a metal and a polymer.

9. The slide-and-lock stent of claim 8, wherein the polymer comprises a bioresorbable polymer.

10. The slide-and-lock stent of claim 8, wherein the polymer comprises a radiopaque bioresorbable polymer.

11. The slide-and-lock stent of claim 8, wherein the polymer forms a coating on at least a portion of the stent.

12. The slide-and-lock stent of claim 11, wherein the polymer coating further comprises a biocompatible, bioresorbable polymer adapted to promote a selected response.

13. The slide-and-lock stent of claim 11, wherein the coating comprises a bioresorbable polymer.

14. The slide-and-lock stent of claim 1, wherein the stent further comprises at least two materials.

15. The slide-and-lock stent of claim 14, wherein the at least two materials comprise a structural configuration selected from the group consisting of materials that are stacked in a radial axis of the stent, materials that vary along a longitudinal axis of the stent, mixed materials, fused materials, coated materials, and materials that vary among structurally distinct elements.

16. The slide-and-lock stent of claim 1, wherein the stent further comprises a therapeutic agent.

17. The slide-and-lock stent of claim 1, further comprising a retractable sheath sized for enclosing the stent during delivery to a treatment site.

18. The slide-and-lock stent of claim 1, further comprising a solid wall region.

19. The slide-and-lock stent of claim 18, wherein said solid wall region further comprises an opening.

20. The slide-and-lock stent of claim 1, further comprising a polymeric sheath.

21. A system for treating a site within a vessel, comprising a catheter having a deployment means, and the stent of claim 1, wherein said catheter is adapted to deliver the stent to said site and said deployment means is adapted to deploy the stent.

22. The system of claim 21, wherein said catheter is selected from the group consisting of over-the-wire catheters, coaxial rapid-exchange catheters, and multi-exchange delivery catheters.

23. The system of claim 21, wherein the stent further comprising a coating adapted to alter a physical characteristic of the stent.

24. The system of claim 23, wherein said coating is further adapted to form frangible bonds between the stent and said catheter, such that the stent is retained on said catheter until deployed.

25. The slide-and-lock stent of claim 1, wherein the closed loop of said one radial element is disposed at a free end of the elongate rail of said one radial element and is distal to an attachment point between said one radial element and a first flexible linkage element, wherein the free end of the elongate rail of said one radial element is not coupled with the first flexible linkage element.

26. The slide-and-lock stent of claim 25, wherein the closed loop of said circumferentially adjacent radial element is disposed at a free end of the elongate rail of said circumferentially adjacent radial element and is distal to an attachment point between said circumferentially adjacent radial element and a second flexible linkage element, wherein the free end of the elongate rail of said circumferentially adjacent radial element is not coupled with the second flexible linkage element.

27. A method for re-treatment of a body lumen, comprising the steps of:

deploying to a region of said body lumen a stent of claim 1, wherein said stent is made from a bioresorbable polymer, and resides at said region for a period of time; and

administering to said region, after the period of time, a second treatment.

28. A slide-and-lock stent, comprising a tubular member having a longitudinal axis and a circumference, said tubular member comprising:

a first module comprising a pair of first radial elements and a first flexible linkage element, the first radial elements extending at least partially along the circumference, the first flexible linkage element interconnecting the pair of first radial elements, each first radial element comprising a first elongate rail, a first neck portion and a first closed loop disposed at a distal end of the first elongate rail, the first neck portion being disposed intermediate the first elongate rail and the first closed loop and being narrower than the first elongate rail and the first closed loop; and

a second module comprising a pair of second radial elements and a second flexible linkage element, the second radial elements extending at least partially along the circumference, the second flexible linkage element interconnecting the pair of second radial elements each second radial element comprising a second elongate rail, a second neck portion and a second closed loop disposed at a distal end of the second elongate rail, the second neck portion being disposed intermediate the second elongate rail and the second closed loop and being narrower than the second elongate rail and the second closed loop, such that slots of the second closed loops of the second module can receive the first closed loops of the first module to slidably interconnect the second closed loops of the second module with the first elongate rails of the first module without welding or bonding, the tubular member achieving circumferential expansion with reduced recoil.

29. The slide-and-lock stent of claim 28, wherein the elongate rails of at least one of the radial elements comprise a deflectable tooth.

30. The slide-and-lock stent of claim 29, wherein the elongate rails of at least one of the radial elements have a plurality of deflectable teeth disposed thereon.

31. The slide-and-lock stent of claim 28, wherein the elongate rails of at least one of the radial elements further comprise two rail members with a gap therebetween, the rail members being configured to deflect toward one another into the gap when engaged by a respective slot.

32. The slide-and-lock stent of claim 31, wherein the rail members deflect in a common plane toward one another.

33. The slide-and-lock stent of claim 31, wherein the elongate rails further comprise a bridge extending intermediate the rail members.

34. The slide-and-lock stent of claim 33, wherein the bridge extends intermediate the rail members at approximately a midpoint of the elongate rails.

35. The slide-and-lock stent of claim 28, wherein the radial elements of the first and second modules are circumferentially offset from one another in a zig-zig pattern.

36. The slide-and-lock stent of claim 28, wherein a cross-sectional geometry of at least a portion of the stent is tapered so as to produce generally uniform blood flow characteristics when the stent is placed in a blood vessel lumen.

37. The slide-and-lock stent of claim 28, wherein the stent comprises a bioresorbable polymer.

38. The slide-and-lock stent of claim 28, wherein the stent comprises a radiopaque bioresorbable polymer.

39. The slide-and-lock stent of claim 28, wherein the closed loops of the first radial elements are disposed at free ends of the elongate rails of the first radial elements that are distal to attachment points between the first radial elements and the first flexible linkage element, wherein the free ends of the elongate rails of the first radial elements are not coupled with the first flexible linkage element.

40. The slide-and-lock stent of claim 39, wherein the closed loops of second radial elements are disposed at free ends of the elongate rails of the second radial elements that are distal to attachment points between the second radial elements and second flexible linkage element, wherein the free ends of the elongate rails of the second radial elements are not coupled with the second flexible linkage element.

41. A slide-and-lock stent comprising:

first and second radial elements extending at least partially about a circumference of the stent, the first and second radial elements each comprising an elongate rail, a flexible linkage element, and a closed loop,

the closed loop of the each of the first and second radial elements being disposed at a free end of the respective elongate rail of each of the first and second radial elements, and the flexible linkage element of each of the first and second radial elements being disposed at an opposing end of the respective elongate rail, the closed loop defining a slot,

the first radial element further comprising a neck portion between the elongate rail and the closed loop, the first radial element narrowing at the neck portion thereof such that the closed loop of the first radial element can be inserted into the slot of the closed loop of the second radial element,

wherein the first and second radial elements are slidably interconnectable without welding or bonding, and the stent achieving circumferential expansion with reduced recoil.

42. The slide-and-lock stent of claim 41, wherein the elongate rail of at least one of the first and second radial elements comprises a deflectable tooth.

43. The slide-and-lock stent of claim 41, wherein the first and second radial elements are longitudinally interconnected with additional radial elements via the flexible linkage element.

44. The slide-and-lock stent of claim 41, wherein the second radial element comprises a neck portion at which the second radial element narrows between the elongate rail and the closed loop thereof.