Methods and apparatus for centrifugal liquid chromatography
First Claim
1. A centrifugal chromatographic system comprising:
- a rotor configured to rotate about an axis;
at least one chromatographic enclosure carried by the rotor; and
a mixing chamber carried by the rotor and arranged to mix a mobile phase fluid with a sample on the rotor to create a mixed fluid, wherein the mixing chamber utilizes the rotation of a component carried by the rotor to enhance the mixing of the sample with the mobile phase fluid, the mixing chamber being located upstream of the chromatographic enclosures.
2 Assignments
0 Petitions
Accused Products
Abstract
Apparatus and methods related to centrifugal liquid chromatography are described. An angular velocity can be simultaneously imparted to a large number of chromatographic enclosures. Via centrifugal forces, a mobile phase fluid including a sample can be driven through a stationary phase within the chromatographic enclosure to perform a chromatographic separation process on components of the sample. The use of centrifugation as a driving force can allow significantly smaller stationary phase particles to be employed as compared to high performance liquid chromatography (HPLC). Further, for an equivalent chromatographic separation process, the use of centrifugation can provide much greater separation efficiencies than HPLC.
-
Citations
9 Claims
-
1. A centrifugal chromatographic system comprising:
-
a rotor configured to rotate about an axis; at least one chromatographic enclosure carried by the rotor; and a mixing chamber carried by the rotor and arranged to mix a mobile phase fluid with a sample on the rotor to create a mixed fluid, wherein the mixing chamber utilizes the rotation of a component carried by the rotor to enhance the mixing of the sample with the mobile phase fluid, the mixing chamber being located upstream of the chromatographic enclosures. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
-
Specification