Medical devices having multiple layers
First Claim
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1. An expandable medical balloon, the expandable medical balloon comprising:
- (a) a polymer layer, the polymer layer defines a balloon wall comprising an inner surface and an outer surface, the inner surface defining a lumen;
(b) a multilayer region comprising;
(i) a charged nanoparticle layer; and
(ii) a plurality of charged polyelectroyte layers comprising charged polyelectrolyte species; and
(c) a therapeutic agent disposed on or within the multilayer region.
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Abstract
Described herein are medical devices which are configured for implantation or insertion into a subject, preferably a mammalian subject. The medical devices contain one or more multilayer regions, which contain: (a) one or more (typically a plurality of) charged nanoparticle layers and (b) one or more (typically a plurality of) charged polyelectroyte layers. Such multilayers have a number of desirable attributes, including high strength, non-compliance, and flexibility. Also described herein are methods of making such devices.
37 Citations
20 Claims
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1. An expandable medical balloon, the expandable medical balloon comprising:
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(a) a polymer layer, the polymer layer defines a balloon wall comprising an inner surface and an outer surface, the inner surface defining a lumen; (b) a multilayer region comprising; (i) a charged nanoparticle layer; and (ii) a plurality of charged polyelectroyte layers comprising charged polyelectrolyte species; and (c) a therapeutic agent disposed on or within the multilayer region. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification