Multilayer laminate wound dressing

• US 8,293,964 B2
• Filed: 10/29/2007
• Issued: 10/23/2012
• Est. Priority Date: 09/05/1995
• Status: Expired due to Fees

• Current Assignee: Argentum Medical LLC
• Original Assignee: Argentum Medical LLC
• Inventors: Becker, Robert O., Flick, A. Bartholomew, Becker, Adam J.
• Primary Examiner(s): Lewis, Kim M
• Application Number:
  US11/927,065
• Publication Number:
  US 20080114279A1
• Time in Patent Office: 1,821 Days
• Field of Search: 424445-449, 602 41- 59, 604304-308
• US Class Current: 602/48
• CPC Class Codes: A61F 13/00051 Accessories for dressings
• CPC Class Codes: A61F 13/023 wound covering film layers without a fluid retention layer
• CPC Class Codes: A61F 2013/00936 metal
• CPC Class Codes: A61L 15/46 Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
• CPC Class Codes: A61L 2300/104 Silver, e.g. silver sulfadiazine
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/608 having two or more layers
• CPC Class Codes: A61N 1/0436 Material of the electrode
• CPC Class Codes: A61N 1/0448 Drug reservoir
• CPC Class Codes: A61N 1/0464 Specially adapted for promoting tissue growth
• CPC Class Codes: A61N 1/0468 Specially adapted for promoting wound healing
• CPC Class Codes: B32B 2307/7145 Rot proof, resistant to bacteria, mildew, mould, fungi
• CPC Class Codes: B32B 2307/724 Permeability to gases, adsorption
• CPC Class Codes: B32B 2307/7265 Non-permeable
• CPC Class Codes: B32B 33/00 Layered products characterised by particular properties or particular surface features, e.g. particular surface coatings; Layered products designed for particular purposes not covered by another single class
• CPC Class Codes: B32B 5/02 characterised by structural features of a fibrous or filamentary layer layer formed of metallic wires B32B15/02; layer formed of natural mineral fibres B32B19/02; layer formed of wood fibres B32B21/02
• CPC Class Codes: Y10T 156/10 Methods of surface bonding and/or assembly therefor
• CPC Class Codes: Y10T 428/249921 Web or sheet containing structurally defined element or component
• CPC Class Codes: Y10T 428/31678 Of metal

Abstract

A flexible, multilayer wound dressing with antibacterial and antifungal properties, together with methods for making the dressing. The dressing includes a layer of silver-containing fabric, a layer of absorbent material, and (optionally) a layer of flexible air-permeable and/or water-impermeable material. The dressing can be used for prophylactic and therapeutic care and treatment of skin infections and surface wounds (including surgical incisions), as a packing material, and as a swab for surface cleaning.

Claims

1. A wound dressing, comprising:

a flexible, conformable fabric substrate comprising an effective amount of silver-coated fibers worked into or forming the flexible, conformable fabric substrate to passively release an effective amount of silver from the wound dressing into a wound at a steady rate for as long as three days when the wound dressing contacts saline, wound exudate or water at the wound, wherein the flexible, conformable fabric substrate has a specific resistance no greater than approximately 5 μ

/cm.

2. The wound dressing of claim 1, wherein the flexible, conformable fabric substrate comprises at least approximately 5 wt. % silver.

3. The wound dressing of claim 1, wherein the flexible, conformable fabric substrate comprises at least approximately 20 wt. % silver.

4. The wound dressing of claim 1, wherein the flexible, conformable fabric substrate has a specific resistance no greater than approximately 1 Ω

/cm.

5. The wound dressing of claim 1, wherein the silver is loosely bound to the plurality of fibers.

6. The wound dressing of claim 1, wherein the wound is a traumatic wound.

7. The wound dressing of claim 6, wherein the traumatic wound is a decubital ulcer.

8. A wound dressing, comprising:

a flexible fabric substrate comprising silver-coated fibers; and

a layer of moisture-absorbing material attached to said substrate, wherein the silver and the substrate have a combined weight, wherein the quantity of silver is at least approximately 5 wt. % of the combined weight, and wherein an effective amount of silver is passively released at a steady rate for as long as three days at a treatment site from the wound dressing without application of an electric current when the wound dressing contacts saline, wound exudate or water at the treatment site.

9. The wound dressing of claim 8, wherein the silver and the substrate have a combined weight, and wherein the silver is at least approximately 20 wt. % of said combined weight.

10. The wound dressing of claim 8, wherein the fibers are nylon.

11. The wound dressing of claim 8, further comprising a third layer adjacent to said layer of moisture-absorbing material, said third layer made of water-impermeable material.

12. The wound dressing of claim 8, further comprising a third layer adjacent to said layer of moisture-absorbing material, said third layer made of an air-permeable material.

13. The wound dressing of claim 8, wherein said moisture-absorbing material is made of cotton.

14. The wound dressing of claim 8, further comprising an adhesive layer attached to at least a portion of said moisture-absorbing material said for adhering said dressing to intact skin.

15. The dressing as recited in claim 8, further comprising:

a third layer adjacent to said layer of moisture-absorbing material, said third layer made of a water-impermeable material; and

an adhesive carried by at least a portion of said third layer, said adhesive positioned so that said adhesive adheres to intact skin when said dressing is placed in contact with a wound.

16. The wound dressing of claim 8, wherein the moisture-absorbing material absorbs wound exudate through the fabric substrate.