Systems and methods of reducing artifact in neurological stimulation systems
First Claim
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1. A system to reduce artifact in a signal acquired from a subject, the system comprising:
- a sensing assembly adapted to acquire a signal from a subject indicative of the subject'"'"'s brain activity;
a stimulation assembly adapted to stimulate one or more neurons of the subject; and
a timing controller programmed to control the time the sensing assembly is powered to acquire the signal such that the sensing assembly is powered at a substantially different time than the time when the stimulation assembly stimulates the subject and that the sensing assembly is not powered to acquire the signal during the time the stimulation assembly stimulates the subject,wherein the acquisition time and the stimulation time are variable based upon the subject'"'"'s predicted susceptibility to having a seizure.
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Abstract
The present invention relates to neurological systems and methods of use which acquire physiological signals from a subject and stimulate the subject. The system is adapted to control the timing at which the system acquires the physiological signals from the subject and the timing of the stimulation signal to reduce the amount of stimulation induced artifact that is acquired by the system.
509 Citations
54 Claims
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1. A system to reduce artifact in a signal acquired from a subject, the system comprising:
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a sensing assembly adapted to acquire a signal from a subject indicative of the subject'"'"'s brain activity; a stimulation assembly adapted to stimulate one or more neurons of the subject; and a timing controller programmed to control the time the sensing assembly is powered to acquire the signal such that the sensing assembly is powered at a substantially different time than the time when the stimulation assembly stimulates the subject and that the sensing assembly is not powered to acquire the signal during the time the stimulation assembly stimulates the subject, wherein the acquisition time and the stimulation time are variable based upon the subject'"'"'s predicted susceptibility to having a seizure. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A method of reducing artifact in a signal acquired from a subject, the method comprising:
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powering signal acquisition circuitry to acquire a signal from a subject indicative of the subject'"'"'s brain activity; stimulating the subject; controlling the time during which the powering signal acquisition circuitry occurs such that the signal acquisition circuitry is powered at a substantially different time than the time during which stimulating the subject occurs and that the signal acquisition circuitry is not powered to acquire the signal during said stimulating the subject; and varying the acquiring time and the stimulating time based upon the subject'"'"'s predicted susceptibility to having a seizure. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45)
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46. A method of managing seizures, the method comprising:
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acquiring an EEG signal from a subject during multiple discrete acquisition times; stimulating one or more neurons of the subject during multiple discrete stimulation times; controlling the time during which signal acquisition circuitry is powered to acquire the EEG signal such that the signal acquisition circuitry is powered at a substantially different time than the time during which the stimulating occurs and that the signal acquisition circuitry is not powered to acquire the EEG signal during the time the stimulating occurs; and varying the acquisition times and the stimulation times based upon the subject'"'"'s predicted susceptibility to having a seizure. - View Dependent Claims (47, 48, 49, 50, 51, 52, 53, 54)
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Specification