Electrode assembly with fibers for a medical device

• US 8,295,946 B2
• Filed: 05/23/2011
• Issued: 10/23/2012
• Est. Priority Date: 01/26/2007
• Status: Expired due to Fees

• Current Assignee: LivaNova USA, Inc. (LivaNova Plc)
• Original Assignee: Cyberonics, Inc
• Inventors: Inman, D. Michael
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Stice, Paula J
• Application Number:
  US13/113,737
• Publication Number:
  US 20110224767A1
• Time in Patent Office: 519 Days
• Field of Search: 607/118, 607125-128, 600/393
• US Class Current: 607/118
• CPC Class Codes: A61N 1/0556 Cuff electrodes
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor

Abstract

An electrode assembly includes an electrode adapted to at least partially surround a first longitudinal portion of a target nerve or nerve bundle. The electrode includes an inner surface adapted to contact an outer surface of the target nerve or nerve bundle. The electrode also includes a plurality of fiber elements each having a proximal end and a distal end. The fiber elements are coupled at the proximal ends to the inner surface of the electrode and the distal ends of the fiber elements are operative to penetrate the outer surface of the target nerve or nerve bundle.

Claims

1. An electrode assembly comprising:

an electrode adapted to fully encircle a first longitudinal portion of a target nerve or nerve bundle, said electrode comprising;

an inner surface adapted to contact an outer surface of said target nerve or nerve bundle, and

a plurality of fiber elements each comprising a proximal end and a distal end, wherein said plurality of fiber elements are coupled at said proximal ends to said inner surface of said electrode and said distal ends of said plurality of fiber elements are operative to penetrate said outer surface of said target nerve or nerve bundle.

2. The electrode assembly of claim 1, wherein said distal ends of said plurality of fiber elements are operative to penetrate said outer surface of said target nerve or nerve bundle by migrating into an inner portion of said target nerve or nerve bundle.

3. The electrode assembly of claim 2, wherein said distal ends of said plurality of fiber elements migrate into said inner portions of said target nerve or bundle in response to one or more electrical pulses provided to the electrode.

4. The electrode assembly of claim 1, wherein said plurality of fiber elements are comprised of a conductive material including at least one of copper, titanium, an alloy metal, iron, steel, and a carbon-based structure.

5. The electrode assembly of claim 1, wherein each of said plurality of fiber elements comprises an electrically insulated portion proximate to said proximal end and a conductive portion proximate to said distal end, and wherein said electrically insulated portion of each of said plurality of fiber elements is encapsulated with an electrically insulating material and the conductive portion is electrically exposed.

6. The electrode assembly of claim 5, further comprising:

a second electrode having a second conductive portion disposed on a second inner surface of the second electrode, the second conductive portion operative to contact said outer surface of said target nerve or nerve bundle; and

wherein the plurality of fiber elements of the conductive portion of the electrode are operative to contact an inner portion of said target nerve or nerve bundle.

7. The electrode assembly of claim 6, wherein the conductive portion is operative to provide a first electrical signal to said inner portion of said target nerve or nerve bundle at a first time and the second conductive portion is operative to provide a second electrical signal to said outer surface of said target nerve or nerve bundle at a second time.

8. The electrode assembly of claim 6, wherein the conductive portion is operative to sense a first electrical activity at said inner portion of said target nerve or nerve bundle at a first time and the second conductive portion is operative to sense a second electrical activity at said outer surface of said target nerve or nerve bundle at a second time.

9. The electrode assembly of claim 1, wherein at least a portion of said inner surface of said electrode is substantially nonconductive.

10. The electrode assembly of claim 1, wherein said target nerve or nerve bundle is a cranial nerve including at least one of a vagus nerve, a glossopharyngeal nerve, and a trigeminal nerve.

11. The electrode assembly of claim 1, wherein said plurality of fiber elements comprise a variety of lengths adapted to penetrate a plurality of distances into said target nerve or nerve bundle.

12. The electrode assembly of claim 1, wherein said electrode is operative to apply an electrical signal to said target nerve or nerve bundle to treat at least one of a depression disorder and an epilepsy disorder.

13. The electrode assembly of claim 1, further comprising:

a second electrode adapted to at least partially surround a second longitudinal portion of said target nerve or nerve bundle, said second electrode comprising;

an inner surface adapted to contact said outer surface of said target nerve or nerve bundle, and

a second plurality of fiber elements each comprising a proximal end and a distal end, wherein said second plurality of fiber elements are coupled at said proximal ends to said inner surface of said second electrode and said distal ends of said second plurality of fiber elements are operative to penetrate said outer surface of said target nerve or nerve bundle.

14. The electrode assembly of claim 13, wherein the electrode is a circumneural cathode and the second electrode is a circumneural anode.

15. The electrode assembly of claim 1, wherein the electrode is operative to sense an electrical activity in said target nerve or nerve bundle.

16. The electrode assembly of claim 1, further comprising:

a non-conductive support member configured to substantially surround the first longitudinal portion of said target nerve or nerve bundle, the electrode disposed on said non-conductive support member.

17. An electrode assembly comprising:

a circumneural cathode adapted to substantially surround a first longitudinal portion of a cranial nerve;

a circumneural anode adapted to substantially surround a second longitudinal portion of said cranial nerve;

wherein said circumneural cathode and circumneural anode each comprise;

a first surface adapted to contact said cranial nerve; and

a plurality of fibers, each of said fibers having a proximal end and a distal end, wherein each of said fibers is coupled to said first surface at said proximal end, said fibers being conductive and adapted to penetrate an outer surface of the cranial nerve.

18. The electrode assembly of claim 17, wherein said first surface is a surface of a helical structure adapted to be wrapped around said cranial nerve, wherein at least a portion of said first surface is configured to electrically couple to said cranial nerve.

19. The electrode assembly of claim 17, wherein said plurality of fibers are oriented generally perpendicular to said first surface.

20. The electrode assembly of claim 17, wherein said plurality of fibers are comprised of a shape-memory metal configured to return to a desired orientation upon reaching a threshold temperature.

21. The electrode assembly of claim 17, wherein said plurality of fibers are comprised of a carbon nanotube structure.

22. An implantable medical device system for providing an electrical signal therapy to a patient, the implantable medical device system comprising:

an implantable medical device configured to generate an electrical signal; and

an electrode assembly that, when operatively coupled to said implantable medical device, is operable to provide said electrical signal generated by the implantable medical device to a target tissue, said electrode assembly comprising an electrode adapted to fully encircle a portion of the target tissue, said electrode comprising;

a first surface adapted to electrically couple to an outer surface of said target tissue; and

a plurality of fibers coupled to said first surface, said plurality of fibers being adapted to electrically couple to at least one of said outer surface and an interior portion of said target tissue.

23. The implantable medical device system of claim 22, further comprising a lead assembly, said lead assembly comprising a proximal portion adapted to be connected to the implantable medical device and a distal portion being adapted to be coupled to said electrode.

24. The implantable medical device system of claim 22, wherein said plurality of fibers are configured to migrate into said interior portion of said target tissue.

25. The implantable medical device system of claim 22, wherein said electrode is a circumneural cathode or a circumneural anode.