Reactive oxygen species measuring device
First Claim
1. A reactive oxygen species measuring device comprising:
- A reactive oxygen species sensor provided with an electrode assembly having a working electrode and a counter electrode formed into a shape enabling the detection of the presence of an in-vivo active oxygen species in terms of an electric current, said electrode assembly being selected from the group consisting of a catheter-shape capable of being inserted into a blood vessel and a pierce shaft-shape capable of being bonded to a surface of a skin,A power source means for applying a measuring voltage to said reactive oxygen species sensor, andA reactive oxygen species concentration measuring means for measuring a concentration of the reactive oxygen species or the like from said current detected by said reactive oxygen species sensor; and
whereinThe working electrode of said reactive oxygen species sensor includes, on its surface, an element capable of detecting the presence of active oxygen species or the like in terms of an electric current;
said element capable of detecting the presence of reactive oxygen species in terms of an electric current consists of a polymerized film of a metal porphyrin complex; and
said metal porphyrin complex is represented by the following formula (II);
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Abstract
A reactive oxygen species measuring device according to the present invention comprises a reactive oxygen species sensor provided with an electrode assembly capable of detecting the presence of reactive oxygen species or the like in terms of an electric current, a power source means for applying a measuring voltage to the reactive oxygen species sensor, and a reactive oxygen species concentration measuring means for measuring a concentration of the reactive oxygen species or the like from the current detected by the reactive oxygen species sensor. According to the present invention, a concentration of reactive oxygen species or the like such as in vivo or in vitro superoxide anion radical (O2−.) can be measured reliably, and the entire device can be formed in a smaller size and always mounted to a living body.
6 Citations
10 Claims
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1. A reactive oxygen species measuring device comprising:
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A reactive oxygen species sensor provided with an electrode assembly having a working electrode and a counter electrode formed into a shape enabling the detection of the presence of an in-vivo active oxygen species in terms of an electric current, said electrode assembly being selected from the group consisting of a catheter-shape capable of being inserted into a blood vessel and a pierce shaft-shape capable of being bonded to a surface of a skin, A power source means for applying a measuring voltage to said reactive oxygen species sensor, and A reactive oxygen species concentration measuring means for measuring a concentration of the reactive oxygen species or the like from said current detected by said reactive oxygen species sensor; and
whereinThe working electrode of said reactive oxygen species sensor includes, on its surface, an element capable of detecting the presence of active oxygen species or the like in terms of an electric current; said element capable of detecting the presence of reactive oxygen species in terms of an electric current consists of a polymerized film of a metal porphyrin complex; and said metal porphyrin complex is represented by the following formula (II); - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification