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Method and apparatus for forming delivery devices for oral intake of an agent

  • US 8,298,574 B2
  • Filed: 01/18/2007
  • Issued: 10/30/2012
  • Est. Priority Date: 01/18/2006
  • Status: Active Grant
First Claim
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1. A method for producing an agent delivery device for oral intake comprising:

  • (i) assembling one or more layers comprising one or more materials with an agent or agent-releasing formulation into a generally planer assembly to form an integrated device;

    (ii) placing said integrated device in between two opposite faces of a press, each face having a corrugated surface with ridges of one corrugated surface being essentially opposite to troughs of the other corrugated surface and essentially fitting one into the other;

    (iii) pressing the two opposite faces one versus the other such that an undulated, three dimensional device is formed with undulations that correspond in shape to that of said corrugated surfaces;

    (iv) folding said integrated delivery device to form a folded integrated delivery device defining a first axis, such that the folded device has folds of increasingly smaller amplitudes upon extending away from the first axis in both directions so as to form a partially rounded cross section and wherein said folding comprises applying a press so as to push sides of the undulated device in a direction perpendicular to said undulation, into a folded device having folds formed along ridges and troughs of the undulation; and

    (v) at least partially enclosing said folded delivery device to a form suitable for oral delivery.

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