Method and apparatus for forming delivery devices for oral intake of an agent
First Claim
1. A method for producing an agent delivery device for oral intake comprising:
- (i) assembling one or more layers comprising one or more materials with an agent or agent-releasing formulation into a generally planer assembly to form an integrated device;
(ii) placing said integrated device in between two opposite faces of a press, each face having a corrugated surface with ridges of one corrugated surface being essentially opposite to troughs of the other corrugated surface and essentially fitting one into the other;
(iii) pressing the two opposite faces one versus the other such that an undulated, three dimensional device is formed with undulations that correspond in shape to that of said corrugated surfaces;
(iv) folding said integrated delivery device to form a folded integrated delivery device defining a first axis, such that the folded device has folds of increasingly smaller amplitudes upon extending away from the first axis in both directions so as to form a partially rounded cross section and wherein said folding comprises applying a press so as to push sides of the undulated device in a direction perpendicular to said undulation, into a folded device having folds formed along ridges and troughs of the undulation; and
(v) at least partially enclosing said folded delivery device to a form suitable for oral delivery.
2 Assignments
0 Petitions
Accused Products
Abstract
Methods, systems and apparatuses are provided for producing delivery devices, preferably for oral intake of an agent. In the broadest aspect, the method comprises assembling one or more layers comprising one or more materials with an agent or an agent-releasing formulation to form an intergraded, preferably laminated device; folding said integrated delivery device to form a folded integrated delivery device; and at least partially enclosing said folded delivery device to a form suitable for oral delivery. Preferably, the integrated device comprise a first external layer of a first material; a frame of a second material mounted on the first external layer; an agent-releasing formulation housed within the frame; and a second external layer of the first material mounted on the frame.
-
Citations
15 Claims
-
1. A method for producing an agent delivery device for oral intake comprising:
-
(i) assembling one or more layers comprising one or more materials with an agent or agent-releasing formulation into a generally planer assembly to form an integrated device; (ii) placing said integrated device in between two opposite faces of a press, each face having a corrugated surface with ridges of one corrugated surface being essentially opposite to troughs of the other corrugated surface and essentially fitting one into the other; (iii) pressing the two opposite faces one versus the other such that an undulated, three dimensional device is formed with undulations that correspond in shape to that of said corrugated surfaces; (iv) folding said integrated delivery device to form a folded integrated delivery device defining a first axis, such that the folded device has folds of increasingly smaller amplitudes upon extending away from the first axis in both directions so as to form a partially rounded cross section and wherein said folding comprises applying a press so as to push sides of the undulated device in a direction perpendicular to said undulation, into a folded device having folds formed along ridges and troughs of the undulation; and (v) at least partially enclosing said folded delivery device to a form suitable for oral delivery. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
-
Specification