Device for measuring biomedical data of a test subject and method for stimulating the test subject using data processed in real time

• US 8,301,222 B2
• Filed: 03/23/2007
• Issued: 10/30/2012
• Est. Priority Date: 04/15/2006
• Status: Expired due to Fees

• Current Assignee: Forschungszentrum Jã¼Lich GmbH (Bundesrepublik Deutschland)
• Original Assignee: Forschungszentrum Jã¼Lich GmbH (Bundesrepublik Deutschland)
• Inventors: Rongen, Heinz, Ziemons, Karl, Schiek, Michael, Tass, Peter Alexander
• Primary Examiner(s): Borin, Michael
• Application Number:
  US12/226,289
• Publication Number:
  US 20090069662A1
• Time in Patent Office: 2,048 Days
• Field of Search: None
• US Class Current: 600/409
• CPC Class Codes: A61B 5/246 using evoked responses
• CPC Class Codes: A61B 5/30 Input circuits therefor
• CPC Class Codes: A61B 5/31 for electroencephalography [EEG]
• CPC Class Codes: A61B 5/375 using biofeedback
• CPC Class Codes: A61B 5/378 Visual stimuli
• CPC Class Codes: A61N 1/08 Arrangements or circuits for monitoring, protecting, controlling or indicating for external stimulators A61N1/3603; for implantable neurostimulators A61N1/36128; for heart stimulators A61N1/37; for defibrillators A61N1/3925

Abstract

Provided is a device for measuring biomedical data from a testee, with a recording system for taking the data and a first hardware component for displaying the data. A device for electrical separation of the data is arranged in a connector line for transmitting the data from the recording system to the first hardware component for displaying the data. At least a duplication of the data for data processing purposes is thus guaranteed. The data processed in said manner are used for a method for real-time stimulation of a testee.

Claims

1. A device for measuring biomedical data of a test subject, comprising:

a measuring system for acquisition of the data, the measuring system coupled to a test subject and having multiple channels for detecting signals from the test subject, the detected signals comprising acquired data;

a first hardware component for recording the data,

a data acquisition and processing unit,

at least one connecting line for transmitting the data from the measuring system to the first hardware component, and

a device for electrical isolation of the data on the connecting line, between the measuring system for acquisition of the data and the first hardware component for recording the data,

wherein the electrical isolation device passively couples an input line to each of a first output line and a second output line, the electrical isolation device providing electrical isolation among signals traversing the input line, the first output line and the second output line, respectively,

wherein the input line connects the measuring system to the electrical isolation device and propagates the detected signals from the multiple channels of the measuring system;

wherein the first hardware component comprises a first computing system, coupled to the measuring system, including memory for storing the acquired data and a processor for controlling acquisition of data by the measuring system;

wherein the data acquisition and processing unit is distinct from the measuring system and the first computing system and generates feedback signals to stimulate either one or both of brain tissue and other tissue of the test subject;

wherein the first output line connects the electrical isolation device to the first computing system and propagates the detected signals from the multiple channels of the measuring system from the electrical isolation device to the first computing system;

wherein the second output line connects the electrical isolation device to the data acquisition and processing unit and propagates the data signals from the multiple channels of the measuring system from the electrical isolation device to the data acquisition and processing unit;

wherein a first connection path is formed between the measuring system and first computing system by the input line, electrical isolation device, and first output line;

wherein a second connection path is formed between the measuring system and the first computing system, distinct from and independent of the first connection path, and along which the first computing system sends control signals to the measuring system to control acquisition of data along the first connection path; and

wherein the measuring system acquires data on an ongoing basis and the data acquisition and procession unit comprises a processing unit which processes currently acquired data in real time to generate in response said feedback signals for stimulating the test subject responsive to each acquisition of acquired data, said feedback signals being distinct from the control signals.

2. A device according to claim 1, in which the electrical isolation device comprises an optical fiber coupler or an electrical isolation amplifier as a passive means for isolating the detected signals propagating along the input line, first output line and second output line, respectively.

3. The device according to claim 1, wherein the data acquisition and processing unit comprises components disposed on a PCI mainboard.

4. A device according to claim 3, wherein the data acquisition and processing unit comprises a field programmable gate array.

5. A device according to claim 1, wherein the data acquisition and processing unit comprises a digital signal processor.

6. A device according to claim 1, further comprising an output component, which receives the feedback signals from the data acquisition and processing unit and forwards the feedback signals to stimulate the test subject.

7. The device according to claim 6, wherein the output component comprises stimulation goggles and/or a sound source.

8. The device according to claim 1, in which the measuring system and the first hardware component together comprise an electroencephalograph or magnetoencephalograph.

9. A method for real-time stimulation of a test subject using the device of claim 1, comprising the following steps:

a) biomedical data of the test subject is acquired by a measuring system,

b) the acquired data is electrically isolated by the measuring system and copied,

c) a copy of the data is processed, and

d) the processed data is forwarded to the test subject in real time.

10. The method according to the preceding claim 9, comprising repetition of steps a) to d).

11. A method according to any one of claim 9 or 10, wherein copies of each of the acquired data and the processed data are continuously saved.

12. A method according to any one of claim 9 or 10, wherein the data is transformed in a linear or non-linear manner and returned to the test subject with a time delay.

13. A device according to claim 3, wherein the data acquisition and processing unit comprises a digital signal processor.

14. A device according to claim 4, wherein the data acquisition and processing unit comprises a digital signal processor.