Prevention and treatment of oxidative stress disorders by glutathione and phase II detoxification enzymes
First Claim
1. A method of protecting a subject from photooxidation consisting of administering to the subject an effective amount of a compound that elevates intracellular levels of glutathione or intracellular levels of at least one Phase II detoxification enzyme in a tissue of said subject, wherein the compound is selected from the group consisting of an isothiocyanate and a glucosinolate.
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Abstract
The present invention generally relates to the field of treating oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracelluar levels of at least one Phase II detoxification enzyme in animal tissue. The present invention also relates to the field of protecting a subject from oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracelluar levels of at least one Phase II detoxification enzyme in the subject. The present invention also relates to a pharmaceutical composition useful for the treatment of oxidative stress disorders.
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Citations
8 Claims
- 1. A method of protecting a subject from photooxidation consisting of administering to the subject an effective amount of a compound that elevates intracellular levels of glutathione or intracellular levels of at least one Phase II detoxification enzyme in a tissue of said subject, wherein the compound is selected from the group consisting of an isothiocyanate and a glucosinolate.
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