Implantable sensing arrangement and approach
First Claim
1. A negligibly-intrusive method for monitoring brain activity in a cerebral cortex, the method comprising:
- displacing part of an anatomical layer adjacent the cerebral cortex with an integrated circuit having an optics layer including an emitter and an array of detectors, for directing electromagnetic radiation into the cerebral cortex, detecting a response of the cerebral cortex to the electromagnetic radiation and using the detected response to assimilate neural data, and whereindetecting a response of the cerebral cortex includes detecting a response indicative of epilepsy during an intraoperative procedure, andusing the detected response to assimilate neural data includes using the detected response to identify a condition of epilepsy during the intraoperative procedure.
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Abstract
Characteristics of biological substances, such as cerebral cortex matter, are sensed. According to an example embodiment, the present invention is directed to a negligibly-intrusive, multi-layer integrated circuit arrangement for monitoring activity of an area of a cerebral cortex that would normally be covered by an anatomical layer. The multi-layer integrated circuit arrangement includes an optics layer located outside the cerebral cortex area that includes an emitter and a detector. The optics layer is adapted for implantation in the anatomical layer and for sensing at least one brain-activity parameter. The multi-layered integrated circuit arrangement also includes a data-processing layer that includes a digital-processing circuit that is adapted for assimilating neural data in response to the optics layer sensing at least one brain-activity parameter.
34 Citations
1 Claim
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1. A negligibly-intrusive method for monitoring brain activity in a cerebral cortex, the method comprising:
displacing part of an anatomical layer adjacent the cerebral cortex with an integrated circuit having an optics layer including an emitter and an array of detectors, for directing electromagnetic radiation into the cerebral cortex, detecting a response of the cerebral cortex to the electromagnetic radiation and using the detected response to assimilate neural data, and wherein detecting a response of the cerebral cortex includes detecting a response indicative of epilepsy during an intraoperative procedure, and using the detected response to assimilate neural data includes using the detected response to identify a condition of epilepsy during the intraoperative procedure.
Specification
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Current AssigneeBoard of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
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Original AssigneeBoard of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
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InventorsLevi, Ofer, Thrush, Evan P., Harris, James S., Shenoy, Krishna V., Smith, Stepehn J.
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Primary Examiner(s)Cwern, Jonathan
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Application NumberUS10/979,091Time in Patent Office2,927 DaysField of Search600/473US Class Current600/473CPC Class CodesA61B 2562/046 in a matrix arrayA61B 5/0031 Implanted circuitryA61B 5/0071 by measuring fluorescence e...A61B 5/0086 using infrared radiationA61B 5/4064 Evaluating the brain A61B5/...
