Irritation-reducing ocular iontophoresis device
First Claim
1. An ocular iontophoresis device for delivering medication to an eye, comprising;
- a reservoir, the reservoir having a proximal end and a distal end, the proximal end comprising a flexible lip configured to engage the eye for delivery of the medication;
an active electrode disposed in close proximity to the distal end of the reservoir, the active electrode is curved having an inside radius of curvature close to the radius of curvature of a cornea of the eye; and
a medication stored in the reservoir.
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Accused Products
Abstract
The invention provides an ocular iontophoresis device for delivering medication, the device comprising a medication reservoir suitable for being positioned on the eye, at least one medication in solution in the reservoir, an active electrode disposed in the reservoir, and a passive electrode, the device including at least one medication dissolved in non-saline water, the said solution having a pH lying in the range 6.5 to 8.5, the medication having a pKa lying in the range about 5.5 to about 9.5 and includes an active principle which is associated with an additive, such as a dendrimer, a polymer, a nanoparticle, a microsphere, a liposome, or an emulsion, and having an ionic form of valency greater than or equal to 1.
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Citations
9 Claims
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1. An ocular iontophoresis device for delivering medication to an eye, comprising;
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a reservoir, the reservoir having a proximal end and a distal end, the proximal end comprising a flexible lip configured to engage the eye for delivery of the medication; an active electrode disposed in close proximity to the distal end of the reservoir, the active electrode is curved having an inside radius of curvature close to the radius of curvature of a cornea of the eye; and a medication stored in the reservoir. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification